SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 GLN A 220
THR A 219
THR A 191
LEU A 266
 None
 1.35A 3ce6A-5g37A:
undetectable		 3ce6A-5g37A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 GLN A 220
THR A 219
THR A 191
LEU A 266
 None
 1.37A 3ce6C-5g37A:
undetectable		 3ce6C-5g37A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 LEU A 229
SER A 227
ILE A 175
SER A 173
GLY A 174
 None
 1.15A 3ik6B-5g37A:
undetectable
3ik6E-5g37A:
undetectable		 3ik6B-5g37A:
20.90
3ik6E-5g37A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 LEU A 229
SER A 227
ILE A 175
SER A 173
GLY A 174
 None
 1.19A 3iluB-5g37A:
undetectable
3iluE-5g37A:
undetectable		 3iluB-5g37A:
20.90
3iluE-5g37A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 ILE A 175
SER A 173
GLY A 174
LEU A 229
SER A 227
 None
 1.20A 3iluB-5g37A:
undetectable
3iluE-5g37A:
undetectable		 3iluB-5g37A:
20.90
3iluE-5g37A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 7 SER A 320
LEU A 266
PHE A 322
HIS A 218
 None
 0.70A 3o9mA-5g37A:
undetectable		 3o9mA-5g37A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 9 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.16A 3p4wA-5g37A:
undetectable		 3p4wA-5g37A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 9 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.14A 3p4wB-5g37A:
undetectable		 3p4wB-5g37A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.14A 3p4wD-5g37A:
undetectable		 3p4wD-5g37A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.15A 3p4wE-5g37A:
undetectable		 3p4wE-5g37A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 265
PHE A  95
ILE A  66
GLY A  90
PHE A 279
 None
 1.15A 4zdyA-5g37A:
undetectable		 4zdyA-5g37A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 265
PHE A  95
ILE A  66
GLY A  90
PHE A 279
 None
 1.11A 5eskA-5g37A:
undetectable		 5eskA-5g37A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 265
PHE A  95
ILE A  66
GLY A  90
PHE A 279
 None
 1.16A 5eslA-5g37A:
undetectable		 5eslA-5g37A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLU A 296
LEU A 266
ALA A 339
PHE A 264
THR A 288
 None
 1.31A 5hnzB-5g37A:
undetectable		 5hnzB-5g37A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.13A 5mzrC-5g37A:
undetectable		 5mzrC-5g37A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 9 ILE A 256
ILE A 193
VAL A 258
THR A 272
ILE A 275
 None
 1.12A 5mzrD-5g37A:
undetectable		 5mzrD-5g37A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 ILE A 256
VAL A 258
THR A 272
ILE A 275
 None
 0.92A 5mzrE-5g37A:
undetectable		 5mzrE-5g37A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 MET A 208
ILE A  56
LEU A 204
VAL A  75
PHE A  58
 None
 1.46A 5tixB-5g37A:
undetectable		 5tixB-5g37A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5g37 41.9 KDA
INSECTICIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 265
PHE A  95
ILE A  66
GLY A  90
PHE A 279
 None
 1.08A 6e8qA-5g37A:
undetectable		 6e8qA-5g37A:
13.60