SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A  97
HIS A  95
MET A 456
HIS A 396
ASP A 106
 CU  A1465 (-3.1A)
CU  A1463 (-4.1A)
None
CU  A1463 ( 4.8A)
None
 1.16A 1a4lA-5g3fA:
undetectable		 1a4lA-5g3fA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A  97
HIS A  95
MET A 456
HIS A 396
ASP A 106
 CU  A1465 (-3.1A)
CU  A1463 (-4.1A)
None
CU  A1463 ( 4.8A)
None
 1.17A 1a4lC-5g3fA:
undetectable		 1a4lC-5g3fA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
LEU A 146
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.34A 1dmyA-5g3fA:
undetectable		 1dmyA-5g3fA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.29A 1dmyB-5g3fA:
undetectable		 1dmyB-5g3fA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 6 HIS A 172
LEU A 318
LEU A 316
PRO A 211
 None
 1.18A 1hz4A-5g3fA:
undetectable		 1hz4A-5g3fA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.48A 1oe1A-5g3fA:
20.7		 1oe1A-5g3fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.46A 1oe2A-5g3fA:
undetectable		 1oe2A-5g3fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 393
CYH A 445
PRO A 394
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
None
CU  A1464 ( 3.4A)
 1.32A 1oe2A-5g3fA:
undetectable		 1oe2A-5g3fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.49A 1oe3A-5g3fA:
20.9		 1oe3A-5g3fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A 128
PRO A 401
HIS A  95
HIS A 396
HIS A  97
 None
None
CU  A1463 (-4.1A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.1A)
 1.21A 1tmxB-5g3fA:
undetectable		 1tmxB-5g3fA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 LEU A  44
SER A  66
LEU A  72
LEU A  42
 None
 1.16A 1yajA-5g3fA:
undetectable		 1yajA-5g3fA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 LEU A 176
LEU A 283
LEU A 213
LEU A 235
 None
 0.95A 1yajD-5g3fA:
undetectable		 1yajD-5g3fA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 1ydbA-5g3fA:
undetectable		 1ydbA-5g3fA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 1yddA-5g3fA:
undetectable		 1yddA-5g3fA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.22A 1zgfA-5g3fA:
undetectable		 1zgfA-5g3fA:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.22A 2fqdA-5g3fA:
48.5		 2fqdA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.20A 2fqeA-5g3fA:
48.6		 2fqeA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.23A 2fqeA-5g3fA:
48.6		 2fqeA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.23A 2fqeA-5g3fA:
48.6		 2fqeA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.77A 2fqeA-5g3fA:
48.6		 2fqeA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.15A 2fqeA-5g3fA:
48.6		 2fqeA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.21A 2fqfA-5g3fA:
48.4		 2fqfA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 2fqfA-5g3fA:
48.5		 2fqfA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.20A 2fqfA-5g3fA:
48.5		 2fqfA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 2fqfA-5g3fA:
48.5		 2fqfA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.21A 2fqfA-5g3fA:
48.5		 2fqfA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.21A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.42A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.18A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 135
HIS A  95
HIS A 396
HIS A 446
 CU  A1465 (-3.2A)
CU  A1463 (-4.1A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 1.24A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.84A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.14A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.26A 2fqgA-5g3fA:
48.4		 2fqgA-5g3fA:
33.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A 138
VAL A 448
HIS A 446
ALA A 148
TYR A  63
 None
None
CU  A1465 (-3.3A)
None
None
 1.31A 2g70A-5g3fA:
undetectable		 2g70A-5g3fA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 8 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.22A 2gehA-5g3fA:
undetectable		 2gehA-5g3fA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 LEU A  61
PRO A  48
LEU A  88
ARG A 141
 None
 1.42A 2hrcB-5g3fA:
undetectable		 2hrcB-5g3fA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 8 HIS A 444
HIS A 398
HIS A 137
VAL A 142
HIS A  97
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
CU  A1465 (-3.1A)
 1.12A 2it4A-5g3fA:
undetectable		 2it4A-5g3fA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 LEU A  61
PRO A  48
LEU A  88
ARG A 141
 None
 1.42A 2pnjB-5g3fA:
undetectable		 2pnjB-5g3fA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.43A 2xxgA-5g3fA:
undetectable		 2xxgA-5g3fA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.48A 2xxgC-5g3fA:
7.5		 2xxgC-5g3fA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 393
CYH A 445
PRO A 394
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
None
CU  A1464 ( 3.4A)
 1.26A 2xxgC-5g3fA:
7.5		 2xxgC-5g3fA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 GLU A 267
ASP A 392
TYR A 288
 MPD  A1466 (-3.8A)
None
None
 0.86A 2yvlB-5g3fA:
undetectable		 2yvlB-5g3fA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 446
HIS A 135
HIS A 137
HIS A 398
VAL A 399
 CU  A1465 (-3.3A)
CU  A1465 (-3.2A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
None
 1.48A 2zweA-5g3fA:
undetectable
2zweB-5g3fA:
undetectable		 2zweA-5g3fA:
22.17
2zweB-5g3fA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 446
HIS A 135
HIS A 137
HIS A 398
VAL A 399
 CU  A1465 (-3.3A)
CU  A1465 (-3.2A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
None
 1.49A 2zwfA-5g3fA:
undetectable
2zwfB-5g3fA:
undetectable		 2zwfA-5g3fA:
22.17
2zwfB-5g3fA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 446
HIS A 135
HIS A 137
HIS A 398
VAL A 399
 CU  A1465 (-3.3A)
CU  A1465 (-3.2A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
None
 1.48A 2zwgA-5g3fA:
undetectable
2zwgB-5g3fA:
undetectable		 2zwgA-5g3fA:
22.17
2zwgB-5g3fA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.28A 3czvB-5g3fA:
undetectable		 3czvB-5g3fA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.27A 3dcwA-5g3fA:
undetectable		 3dcwA-5g3fA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 3dd0A-5g3fA:
undetectable		 3dd0A-5g3fA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 3hs4A-5g3fA:
undetectable		 3hs4A-5g3fA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A  97
HIS A 135
HIS A  95
 CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
CU  A1463 (-4.1A)
 0.80A 3mihA-5g3fA:
undetectable		 3mihA-5g3fA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 444
HIS A 396
HIS A 398
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.79A 3mihA-5g3fA:
undetectable		 3mihA-5g3fA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.26A 3ml5A-5g3fA:
undetectable		 3ml5A-5g3fA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.37A 3qpkA-5g3fA:
30.3		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 137
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.57A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA603_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 3qpkA-5g3fA:
30.5		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.35A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.20A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.84A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.12A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.18A 3qpkA-5g3fA:
30.4		 3qpkA-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.37A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 137
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.55A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB603_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.20A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.38A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.19A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.84A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.13A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.22A 3qpkB-5g3fA:
30.6		 3qpkB-5g3fA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 6 LEU A  51
ALA A 148
LEU A  61
THR A  62
 None
 1.03A 3rozA-5g3fA:
undetectable		 3rozA-5g3fA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 3v2jA-5g3fA:
undetectable		 3v2jA-5g3fA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 6 PHE A 147
LEU A 146
PRO A 144
GLU A 449
 None
 1.21A 3vlnA-5g3fA:
undetectable		 3vlnA-5g3fA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 PHE A 147
PRO A 136
LEU A  94
TYR A 134
ALA A 227
 None
 1.39A 4a83A-5g3fA:
undetectable		 4a83A-5g3fA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 PHE A 147
PRO A 136
LEU A  94
TYR A 134
ALA A 227
 None
 1.37A 4a84A-5g3fA:
undetectable		 4a84A-5g3fA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 446
GLY A 266
HIS A  95
PRO A 100
 CU  A1463 (-3.0A)
CU  A1465 (-3.3A)
None
CU  A1463 (-4.1A)
None
 1.29A 4bz6C-5g3fA:
undetectable		 4bz6C-5g3fA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.27A 4coqA-5g3fA:
undetectable		 4coqA-5g3fA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 9 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.27A 4coqB-5g3fA:
undetectable		 4coqB-5g3fA:
19.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
HIS A 450
MET A 455
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 (-3.2A)
CU  A1464 ( 3.4A)
 0.21A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  97
HIS A 135
HIS A 396
HIS A 446
 CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 0.22A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 444
HIS A  97
HIS A  95
 CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1465 (-3.1A)
CU  A1463 (-4.1A)
 0.84A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 398
HIS A 444
HIS A  95
HIS A 137
 CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 0.75A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.55A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 396
HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.70A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.43A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.22A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.86A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.15A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.31A 4ef3A-5g3fA:
48.0		 4ef3A-5g3fA:
33.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 4k0sA-5g3fA:
undetectable		 4k0sA-5g3fA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
LEU A 146
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
None
 1.27A 4k13A-5g3fA:
undetectable		 4k13A-5g3fA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
LEU A 146
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
None
 1.28A 4m2wA-5g3fA:
undetectable		 4m2wA-5g3fA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.26A 4uovC-5g3fA:
undetectable		 4uovC-5g3fA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
LEU A 146
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
None
 1.39A 4xiwG-5g3fA:
undetectable		 4xiwG-5g3fA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 9 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 4ygfF-5g3fA:
undetectable		 4ygfF-5g3fA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.32A 4ygfG-5g3fA:
undetectable		 4ygfG-5g3fA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.26A 5jn8A-5g3fA:
undetectable		 5jn8A-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 5jn8B-5g3fA:
undetectable		 5jn8B-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.26A 5jn9A-5g3fA:
undetectable		 5jn9A-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.28A 5jn9B-5g3fA:
undetectable		 5jn9B-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.28A 5jn9D-5g3fA:
undetectable		 5jn9D-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 5jnaB-5g3fA:
undetectable		 5jnaB-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 5jnaC-5g3fA:
undetectable		 5jnaC-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 12 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.25A 5jnaD-5g3fA:
undetectable		 5jnaD-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.27A 5jncA-5g3fA:
undetectable		 5jncA-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.27A 5jncB-5g3fA:
undetectable		 5jncB-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.26A 5ku6A-5g3fA:
undetectable		 5ku6A-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 444
HIS A 398
HIS A 137
VAL A 448
VAL A 142
 CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
None
None
 1.24A 5ku6B-5g3fA:
undetectable		 5ku6B-5g3fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.51A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 396
HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 6 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 396
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 0.30A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 6 HIS A 396
HIS A 398
HIS A 444
HIS A  95
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 0.80A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.35A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.81A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.08A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.22A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mejA-5g3fA:
35.4		 5mejA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.52A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 396
HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.65A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 444
HIS A 396
HIS A 137
HIS A 398
HIS A  95
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
 1.46A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 6 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 396
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 0.29A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 6 HIS A 396
HIS A 398
HIS A 444
HIS A  95
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 0.81A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.35A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.08A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.21A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mewA-5g3fA:
35.3		 5mewA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.52A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 396
HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.65A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 444
HIS A 396
HIS A 137
HIS A 398
HIS A  95
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
 1.46A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 6 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 396
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 0.29A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 6 HIS A 396
HIS A 398
HIS A 444
HIS A  95
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 0.82A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.34A 5mhuA-5g3fA:
35.3		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mhuA-5g3fA:
35.3		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mhuA-5g3fA:
35.3		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhuA-5g3fA:
35.3		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.19A 5mhuA-5g3fA:
35.3		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.13A 5mhuA-5g3fA:
35.4		 5mhuA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.53A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 396
HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.65A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A 444
HIS A 396
HIS A 137
HIS A 398
HIS A  95
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
 1.47A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		6 / 6 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 396
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 0.29A 5mhvA-5g3fA:
35.3		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 6 HIS A 396
HIS A 398
HIS A 444
HIS A  95
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 0.83A 5mhvA-5g3fA:
35.3		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.34A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.81A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.18A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mhvA-5g3fA:
35.4		 5mhvA-5g3fA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.46A 5mhwA-5g3fA:
35.4		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mhwA-5g3fA:
35.4		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.85A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.33A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.17A 5mhwA-5g3fA:
35.3		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mhwA-5g3fA:
35.4		 5mhwA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.45A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.85A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.16A 5mhxA-5g3fA:
35.4		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.13A 5mhxA-5g3fA:
35.3		 5mhxA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.46A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.85A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.16A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.13A 5mhyA-5g3fA:
35.4		 5mhyA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.15A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mhzA-5g3fA:
35.4		 5mhzA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.23A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.15A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mi1A-5g3fA:
35.4		 5mi1A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mi2A-5g3fA:
35.4		 5mi2A-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.15A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5miaA-5g3fA:
35.4		 5miaA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.48A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.32A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5mibA-5g3fA:
35.3		 5mibA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5micA-5g3fA:
35.4		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5micA-5g3fA:
35.4		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5micA-5g3fA:
35.4		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5micA-5g3fA:
35.4		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.92A 5micA-5g3fA:
35.4		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.31A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5micA-5g3fA:
35.3		 5micA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.47A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.31A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.14A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.14A 5midA-5g3fA:
35.4		 5midA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 137
HIS A 396
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.48A 5mieA-5g3fA:
35.4		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 446
HIS A  95
HIS A  97
HIS A 135
 CU  A1465 (-3.3A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-3.2A)
 0.66A 5mieA-5g3fA:
35.4		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.22A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.86A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.31A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5mieA-5g3fA:
35.3		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.13A 5mieA-5g3fA:
35.4		 5mieA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 HIS A 137
HIS A 398
HIS A 444
 CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
 0.45A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 5 HIS A  95
HIS A  97
TRP A 133
HIS A 135
HIS A 446
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1465 (-4.1A)
CU  A1465 (-3.2A)
CU  A1465 (-3.3A)
 0.21A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 396
HIS A 398
HIS A 444
HIS A 137
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
 0.87A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 5 HIS A 446
HIS A 396
HIS A 444
HIS A 398
 CU  A1465 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1463 (-3.0A)
CU  A1463 (-2.9A)
 0.91A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A  97
HIS A 396
HIS A 398
 CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
 0.30A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A  95
HIS A 137
HIS A 444
HIS A 396
 CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
 1.15A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 396
HIS A 398
HIS A  95
HIS A  97
 CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1465 (-3.1A)
 0.80A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A  95
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
 1.07A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 444
HIS A 396
HIS A 398
HIS A 137
 CU  A1463 (-3.0A)
CU  A1463 ( 4.8A)
CU  A1463 (-2.9A)
CU  A1463 (-3.3A)
 1.14A 5migA-5g3fA:
35.3		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 393
CYH A 445
ILE A 447
HIS A 450
 CU  A1464 (-3.1A)
CU  A1464 (-2.1A)
CU  A1464 ( 3.9A)
CU  A1464 (-3.2A)
 0.15A 5migA-5g3fA:
35.4		 5migA-5g3fA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 10 HIS A 398
HIS A  95
HIS A 137
HIS A 396
HIS A 446
 CU  A1463 (-2.9A)
CU  A1463 (-4.1A)
CU  A1463 (-3.3A)
CU  A1463 ( 4.8A)
CU  A1465 (-3.3A)
 1.14A 5nzwA-5g3fA:
undetectable		 5nzwA-5g3fA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 ARG A 223
PHE A 251
ARG A 221
 None
 1.21A 5y9yA-5g3fA:
undetectable		 5y9yA-5g3fA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		5 / 11 HIS A 446
HIS A 135
HIS A 137
HIS A 398
VAL A 399
 CU  A1465 (-3.3A)
CU  A1465 (-3.2A)
CU  A1463 (-3.3A)
CU  A1463 (-2.9A)
None
 1.50A 5z0iA-5g3fA:
undetectable
5z0iB-5g3fA:
undetectable		 5z0iA-5g3fA:
11.14
5z0iB-5g3fA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 398
HIS A 444
HIS A 137
HIS A  95
 CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
CU  A1463 (-4.1A)
 1.17A 5zrdC-5g3fA:
undetectable		 5zrdC-5g3fA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		4 / 4 HIS A 398
HIS A 444
HIS A 137
HIS A  95
 CU  A1463 (-2.9A)
CU  A1463 (-3.0A)
CU  A1463 (-3.3A)
CU  A1463 (-4.1A)
 1.17A 5zrdD-5g3fA:
undetectable		 5zrdD-5g3fA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 GLU A 460
LEU A 459
ARG A 346
 None
 0.77A 6d8fA-5g3fA:
undetectable		 6d8fA-5g3fA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE
(Thermus
thermophilus) 		3 / 3 ARG A 370
ARG A 369
ASP A 367
 None
 0.91A 6d8pA-5g3fA:
undetectable		 6d8pA-5g3fA:
21.86