SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 12 GLN A  35
THR A  63
SER A 102
GLY A  65
GLY A 221
 None
 1.09A 1jg4A-5g3pA:
undetectable		 1jg4A-5g3pA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 7 LEU A 133
ILE A 103
THR A 116
GLN A  64
 None
 1.17A 1kglA-5g3pA:
undetectable		 1kglA-5g3pA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 TYR A  98
ILE A 119
GLY A 154
ILE A 127
 None
 0.90A 1mrjA-5g3pA:
undetectable		 1mrjA-5g3pA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 TYR A 191
CYH A 163
TRP A 199
LEU A 185
 SCY  A 165 ( 3.4A)
None
None
None
 1.38A 1uw6A-5g3pA:
undetectable
1uw6B-5g3pA:
undetectable		 1uw6A-5g3pA:
19.54
1uw6B-5g3pA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 TYR A 191
CYH A 163
TRP A 199
LEU A 185
 SCY  A 165 ( 3.4A)
None
None
None
 1.37A 1uw6D-5g3pA:
undetectable
1uw6E-5g3pA:
undetectable		 1uw6D-5g3pA:
19.54
1uw6E-5g3pA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 TYR A 191
CYH A 163
TRP A 199
LEU A 185
 SCY  A 165 ( 3.4A)
None
None
None
 1.39A 1uw6G-5g3pA:
undetectable
1uw6H-5g3pA:
undetectable		 1uw6G-5g3pA:
19.54
1uw6H-5g3pA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 TRP A 199
LEU A 185
TYR A 191
CYH A 163
 None
None
SCY  A 165 ( 3.4A)
None
 1.45A 1uw6P-5g3pA:
undetectable
1uw6T-5g3pA:
undetectable		 1uw6P-5g3pA:
19.54
1uw6T-5g3pA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 7 GLU A  60
GLU A 140
TYR A 191
TYR A  61
 SCY  A 165 ( 3.2A)
SCY  A 165 ( 3.7A)
SCY  A 165 ( 3.4A)
None
 1.05A 3ku9B-5g3pA:
undetectable		 3ku9B-5g3pA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 6 SER A 216
VAL A 257
THR A 241
THR A 240
 None
None
EDO  A1331 (-2.9A)
None
 1.09A 3tneA-5g3pA:
undetectable		 3tneA-5g3pA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 12 VAL A 257
ALA A 255
LEU A  18
PHE A  14
LEU A 160
 None
 1.26A 4eckA-5g3pA:
undetectable		 4eckA-5g3pA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		4 / 8 GLU A  75
ASP A  31
TRP A  71
TRP A 142
 None
 1.20A 4uhxA-5g3pA:
undetectable		 4uhxA-5g3pA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 GLY A  99
VAL A 100
THR A  16
LEU A  18
LEU A 160
 None
 1.22A 4yb6A-5g3pA:
undetectable
4yb6E-5g3pA:
undetectable		 4yb6A-5g3pA:
21.31
4yb6E-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 GLY A  99
VAL A 100
THR A  16
LEU A  18
LEU A 160
 None
 1.23A 4yb6B-5g3pA:
undetectable
4yb6C-5g3pA:
undetectable		 4yb6B-5g3pA:
21.31
4yb6C-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 GLY A  99
VAL A 100
THR A  16
LEU A  18
LEU A 160
 None
 1.31A 4yb6C-5g3pA:
undetectable
4yb6F-5g3pA:
undetectable		 4yb6C-5g3pA:
21.31
4yb6F-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 LEU A  18
LEU A 160
GLY A  99
VAL A 100
THR A  16
 None
 1.32A 4yb6A-5g3pA:
undetectable
4yb6D-5g3pA:
undetectable		 4yb6A-5g3pA:
21.31
4yb6D-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 LEU A  18
LEU A 160
GLY A  99
VAL A 100
THR A  16
 None
 1.33A 4yb6D-5g3pA:
undetectable
4yb6E-5g3pA:
undetectable		 4yb6D-5g3pA:
21.31
4yb6E-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 10 LEU A  18
LEU A 160
GLY A  99
VAL A 100
THR A  16
 None
 1.22A 4yb6B-5g3pA:
undetectable
4yb6F-5g3pA:
undetectable		 4yb6B-5g3pA:
21.31
4yb6F-5g3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		5 / 12 GLY A  13
VAL A 257
GLY A 154
GLY A 157
GLN A 123
 None
 1.05A 5x7fA-5g3pA:
undetectable		 5x7fA-5g3pA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5g3p FORMAMIDASE
(Bacillus
cereus) 		3 / 3 LYS A 159
VAL A 151
ASP A 153
 None
 0.64A 6fgdA-5g3pA:
undetectable		 6fgdA-5g3pA:
22.76