SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.88A 1v54C-5g3yA:
undetectable
1v54J-5g3yA:
undetectable		 1v54C-5g3yA:
19.19
1v54J-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.86A 1v54P-5g3yA:
undetectable
1v54W-5g3yA:
undetectable		 1v54P-5g3yA:
19.19
1v54W-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 12 TYR A 186
ASP A  97
ILE A   4
SER A  30
PHE A  86
 None
None
None
ADP  A1216 ( 4.8A)
ADP  A1216 (-4.8A)
 1.50A 1xoqA-5g3yA:
undetectable		 1xoqA-5g3yA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 12 TYR A 186
ASP A  97
ILE A   4
SER A  30
PHE A  86
 None
None
None
ADP  A1216 ( 4.8A)
ADP  A1216 (-4.8A)
 1.49A 1xoqB-5g3yA:
undetectable		 1xoqB-5g3yA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.89A 2dyrC-5g3yA:
undetectable
2dyrJ-5g3yA:
undetectable		 2dyrC-5g3yA:
19.19
2dyrJ-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.87A 2dyrP-5g3yA:
undetectable
2dyrW-5g3yA:
undetectable		 2dyrP-5g3yA:
19.19
2dyrW-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.89A 2eikP-5g3yA:
undetectable
2eikW-5g3yA:
undetectable		 2eikP-5g3yA:
19.19
2eikW-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.86A 2eilC-5g3yA:
undetectable
2eilJ-5g3yA:
undetectable		 2eilC-5g3yA:
19.19
2eilJ-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.87A 2eimP-5g3yA:
undetectable
2eimW-5g3yA:
undetectable		 2eimP-5g3yA:
19.19
2eimW-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 10 LEU A 124
ASP A 163
ASP A 162
THR A 136
ASP A  33
 None
None
ADP  A1216 (-4.4A)
ADP  A1215 (-3.7A)
None
 1.34A 2q58A-5g3yA:
undetectable		 2q58A-5g3yA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.85A 3asnP-5g3yA:
undetectable
3asnW-5g3yA:
undetectable		 3asnP-5g3yA:
19.19
3asnW-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.89A 3asoP-5g3yA:
undetectable
3asoW-5g3yA:
undetectable		 3asoP-5g3yA:
19.19
3asoW-5g3yA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 12 VAL A  63
LEU A  67
SER A  30
GLY A  46
ALA A  49
 None
None
ADP  A1216 ( 4.8A)
None
None
 0.98A 3kk6A-5g3yA:
undetectable		 3kk6A-5g3yA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 PRO A   8
GLY A  10
ALA A  11
ASP A 198
 None
ADP  A1215 (-3.6A)
ADP  A1215 (-4.0A)
None
 0.84A 3ur0B-5g3yA:
undetectable		 3ur0B-5g3yA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 12 GLY A  12
GLN A  16
ALA A  11
VAL A 115
ILE A 208
 ADP  A1215 (-3.2A)
None
ADP  A1215 (-4.0A)
None
None
 1.20A 4pd5A-5g3yA:
undetectable		 4pd5A-5g3yA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 12 GLY A  12
GLN A  16
ALA A  11
VAL A 115
ILE A 208
 ADP  A1215 (-3.2A)
None
ADP  A1215 (-4.0A)
None
None
 1.17A 4pd9A-5g3yA:
undetectable		 4pd9A-5g3yA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 THR A 136
ARG A 123
GLY A  12
GLY A  14
 ADP  A1215 (-3.7A)
ADP  A1215 (-3.6A)
ADP  A1215 (-3.2A)
ADP  A1215 (-3.6A)
 0.77A 4rdxA-5g3yA:
undetectable		 4rdxA-5g3yA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		5 / 10 GLY A   7
ALA A  93
ILE A   4
LEU A   6
TYR A 186
 None
 1.08A 4xj7A-5g3yA:
2.5
4xj7B-5g3yA:
2.3		 4xj7A-5g3yA:
23.37
4xj7B-5g3yA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 8 VAL A  63
LEU A  67
GLY A  46
ALA A  49
 None
 0.82A 5f1aA-5g3yA:
undetectable		 5f1aA-5g3yA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 6 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.84A 5x19P-5g3yA:
undetectable		 5x19P-5g3yA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g3y ADENYLATE KINSE
(synthetic
construct) 		4 / 7 LYS A  69
LEU A  72
PHE A  81
LEU A  83
 None
 0.85A 5x1fP-5g3yA:
undetectable
5x1fW-5g3yA:
undetectable		 5x1fP-5g3yA:
19.19
5x1fW-5g3yA:
16.27