SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		5 / 12 PHE A 607
VAL A 760
ILE A 734
VAL A 597
LEU A 605
 None
 1.24A 2ft9A-5g47A:
undetectable		 2ft9A-5g47A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.22A 2obvA-5g47A:
undetectable		 2obvA-5g47A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		5 / 9 ALA A 815
ILE A 807
VAL A 712
GLY A 681
ILE A 824
 None
 0.94A 3s43A-5g47A:
undetectable		 3s43A-5g47A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		3 / 3 ARG A 624
GLU A 867
ASN A 626
 None
 0.79A 4imaD-5g47A:
undetectable		 4imaD-5g47A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		3 / 3 ARG A 624
GLU A 867
ASN A 626
 None
 0.79A 4ip7D-5g47A:
undetectable		 4ip7D-5g47A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.20A 4kttA-5g47A:
undetectable		 4kttA-5g47A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.20A 4kttC-5g47A:
undetectable		 4kttC-5g47A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.23A 4ndnA-5g47A:
undetectable		 4ndnA-5g47A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.20A 5a1iA-5g47A:
undetectable		 5a1iA-5g47A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 PHE A 707
SER A 646
TRP A 708
TRP A 673
 None
 1.36A 5amiB-5g47A:
undetectable		 5amiB-5g47A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 4 LEU A 790
ARG A 865
ILE A 861
PHE A 866
 None
 1.16A 5kirB-5g47A:
undetectable		 5kirB-5g47A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		5 / 12 ILE A 886
PRO A 730
LEU A 627
SER A 750
GLY A 888
 None
 1.19A 5l6eA-5g47A:
undetectable		 5l6eA-5g47A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.17A 5t8sB-5g47A:
undetectable		 5t8sB-5g47A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.19A 6fboA-5g47A:
undetectable		 6fboA-5g47A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.22A 6fcbA-5g47A:
undetectable		 6fcbA-5g47A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5g47 SFTSV GC
(SFTS
phlebovirus) 		4 / 8 HIS A 663
PRO A 661
SER A 685
ASP A 655
 None
 1.18A 6fcdA-5g47A:
undetectable		 6fcdA-5g47A:
11.27