SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.66A 1v54C-5g4qA:
undetectable
1v54J-5g4qA:
undetectable		 1v54C-5g4qA:
20.21
1v54J-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.76A 1v54P-5g4qA:
undetectable
1v54W-5g4qA:
undetectable		 1v54P-5g4qA:
20.21
1v54W-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.78A 1v55C-5g4qA:
undetectable
1v55J-5g4qA:
undetectable		 1v55C-5g4qA:
20.21
1v55J-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 9 PHE A 138
VAL A 170
LEU A 168
SER A 219
LEU A 134
 None
 1.44A 1wrkA-5g4qA:
undetectable
1wrkB-5g4qA:
undetectable		 1wrkA-5g4qA:
12.83
1wrkB-5g4qA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.66A 2dyrC-5g4qA:
undetectable
2dyrJ-5g4qA:
undetectable		 2dyrC-5g4qA:
20.21
2dyrJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.72A 2dyrP-5g4qA:
undetectable
2dyrW-5g4qA:
undetectable		 2dyrP-5g4qA:
20.21
2dyrW-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.88A 2dysP-5g4qA:
undetectable
2dysW-5g4qA:
undetectable		 2dysP-5g4qA:
20.21
2dysW-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.74A 2eijC-5g4qA:
undetectable
2eijJ-5g4qA:
undetectable		 2eijC-5g4qA:
20.21
2eijJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.74A 2eikC-5g4qA:
undetectable
2eikJ-5g4qA:
undetectable		 2eikC-5g4qA:
20.21
2eikJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.77A 2eikP-5g4qA:
undetectable
2eikW-5g4qA:
undetectable		 2eikP-5g4qA:
20.21
2eikW-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.73A 2eilC-5g4qA:
undetectable
2eilJ-5g4qA:
undetectable		 2eilC-5g4qA:
20.21
2eilJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 ILE A 157
ALA A 142
PHE A 138
PRO A 132
VAL A 170
 None
 1.23A 2w3aA-5g4qA:
undetectable		 2w3aA-5g4qA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 ILE A  33
LEU A 107
ILE A  70
SER A  80
ILE A  79
 None
 0.96A 2w9sA-5g4qA:
undetectable		 2w9sA-5g4qA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 ILE A  33
LEU A 107
ILE A  70
SER A  80
ILE A  79
 None
 0.97A 2w9sB-5g4qA:
undetectable		 2w9sB-5g4qA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 6 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.74A 2zxwP-5g4qA:
undetectable
2zxwW-5g4qA:
undetectable		 2zxwP-5g4qA:
20.21
2zxwW-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 12 THR A  91
MET A   1
ILE A   3
MET A 109
LEU A  10
 None
 1.10A 3a51D-5g4qA:
undetectable		 3a51D-5g4qA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 6 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.70A 3ag1C-5g4qA:
undetectable
3ag1J-5g4qA:
undetectable		 3ag1C-5g4qA:
20.21
3ag1J-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.96A 3ag2P-5g4qA:
undetectable
3ag2W-5g4qA:
undetectable		 3ag2P-5g4qA:
20.21
3ag2W-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.70A 3ag4C-5g4qA:
undetectable
3ag4J-5g4qA:
undetectable		 3ag4C-5g4qA:
20.21
3ag4J-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.78A 3ag4P-5g4qA:
undetectable
3ag4W-5g4qA:
undetectable		 3ag4P-5g4qA:
20.21
3ag4W-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.75A 3asnC-5g4qA:
undetectable
3asnJ-5g4qA:
undetectable		 3asnC-5g4qA:
20.21
3asnJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 ILE A  98
ILE A  70
LEU A  42
VAL A   5
 None
 0.81A 3ua5B-5g4qA:
undetectable		 3ua5B-5g4qA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.77A 3x2qC-5g4qA:
undetectable
3x2qJ-5g4qA:
undetectable		 3x2qC-5g4qA:
20.21
3x2qJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.91A 3x2qP-5g4qA:
undetectable
3x2qW-5g4qA:
undetectable		 3x2qP-5g4qA:
20.21
3x2qW-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 12 LEU A 332
LEU A 329
LEU A 326
VAL A 320
THR A 367
 None
 1.01A 3zqtA-5g4qA:
undetectable		 3zqtA-5g4qA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 12 ILE A 127
ILE A 121
PHE A 217
LEU A 237
LEU A 199
 None
 1.01A 4m2xA-5g4qA:
undetectable		 4m2xA-5g4qA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 LEU A  42
ALA A  13
ILE A  79
THR A  59
ILE A  57
 None
 0.98A 4njuB-5g4qA:
undetectable		 4njuB-5g4qA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 LEU A  42
ALA A  13
ILE A  79
THR A  59
ILE A  57
 None
 1.00A 4njuD-5g4qA:
undetectable		 4njuD-5g4qA:
13.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 7 LEU A 154
THR A 173
PRO A 243
LEU A 368
MET A 370
 None
 0.55A 5fxtA-5g4qA:
51.1		 5fxtA-5g4qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 8 THR A 173
LEU A 178
PRO A 243
LEU A 368
MET A 370
 None
 0.63A 5g48A-5g4qA:
49.9		 5g48A-5g4qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		6 / 8 THR A 173
THR A 175
LEU A 178
PRO A 243
PRO A 347
LEU A 368
 None
 0.28A 5g48A-5g4qA:
49.9		 5g48A-5g4qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		6 / 9 LEU A 154
THR A 173
LEU A 178
PRO A 243
LEU A 368
MET A 370
 None
 0.69A 5g48B-5g4qA:
51.1		 5g48B-5g4qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		7 / 9 LEU A 154
THR A 173
THR A 175
LEU A 178
PRO A 243
PRO A 347
LEU A 368
 None
 0.36A 5g48B-5g4qA:
51.1		 5g48B-5g4qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		3 / 3 LYS A 364
ASP A 136
ILE A 350
 None
 0.87A 5kc4E-5g4qA:
undetectable		 5kc4E-5g4qA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.67A 5zcoC-5g4qA:
undetectable
5zcoJ-5g4qA:
undetectable		 5zcoC-5g4qA:
20.21
5zcoJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		4 / 7 LEU A 183
GLN A 182
LEU A 134
PHE A 138
 None
 0.77A 5zcqC-5g4qA:
undetectable
5zcqJ-5g4qA:
undetectable		 5zcqC-5g4qA:
20.21
5zcqJ-5g4qA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5g4q DNA POLYMERASE III
SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 VAL A 170
THR A 181
LEU A 204
ALA A 363
VAL A 144
 None
 1.35A 6dryA-5g4qA:
undetectable		 6dryA-5g4qA:
23.17