SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g52'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5g52 VP1
VP3
(Deformed
wing
virus) 		4 / 8 PHE A  26
GLY A  27
TRP C 186
PHE C 114
 None
 0.77A 1fapB-5g52A:
undetectable		 1fapB-5g52A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 5g52 VP2
(Deformed
wing
virus) 		5 / 12 ILE B  84
LEU B  90
SER B  91
HIS B 144
ILE B 199
 None
 1.16A 1fmlB-5g52B:
undetectable		 1fmlB-5g52B:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 5g52 VP1
VP2
(Deformed
wing
virus;
Deformed
wing
virus) 		5 / 12 ALA B 164
GLY A   1
GLU B 173
ALA B 137
LEU B 176
 None
 1.04A 1mjqC-5g52B:
undetectable
1mjqD-5g52B:
undetectable		 1mjqC-5g52B:
16.80
1mjqD-5g52B:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 5g52 VP1
VP2
(Deformed
wing
virus;
Deformed
wing
virus) 		5 / 10 GLU B 173
ALA B 137
LEU B 176
ALA B 164
GLY A   1
 None
 1.04A 1mjqG-5g52B:
undetectable
1mjqH-5g52B:
undetectable		 1mjqG-5g52B:
16.80
1mjqH-5g52B:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 5g52 VP1
VP2
(Deformed
wing
virus;
Deformed
wing
virus) 		5 / 12 ALA B 164
GLY A   1
GLU B 173
ALA B 137
LEU B 176
 None
 1.04A 1mjqI-5g52B:
undetectable
1mjqJ-5g52B:
undetectable		 1mjqI-5g52B:
16.80
1mjqJ-5g52B:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 5g52 VP2
(Deformed
wing
virus) 		3 / 3 ASP B  50
HIS B 112
ASP B  53
 None
 0.75A 1nw5A-5g52B:
undetectable		 1nw5A-5g52B:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 5g52 VP2
(Deformed
wing
virus) 		4 / 8 TYR B 184
ASP B 194
TRP B 195
HIS B 182
 None
 1.22A 1pk2A-5g52B:
undetectable		 1pk2A-5g52B:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 5g52 VP2
(Deformed
wing
virus) 		4 / 8 VAL B 183
TYR B 184
ASP B 194
TRP B 195
 None
 1.06A 1pk2A-5g52B:
undetectable		 1pk2A-5g52B:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 5g52 VP2
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		3 / 3 TYR B 156
ARG B 214
GLN C  69
 None
 0.96A 1tw4A-5g52B:
undetectable		 1tw4A-5g52B:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 5g52 VP1
(Deformed
wing
virus) 		5 / 12 ASN A 181
VAL A 197
GLY A 200
TYR A 175
SER A 203
 None
 1.50A 2cl5A-5g52A:
undetectable		 2cl5A-5g52A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 5g52 VP2
(Deformed
wing
virus) 		4 / 6 LEU B 231
LEU B  89
PRO B 104
VAL B 103
 None
 1.20A 2dqyC-5g52B:
undetectable		 2dqyC-5g52B:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 5g52 VP3
(Deformed
wing
virus) 		4 / 5 PRO C  98
ILE C 314
ARG C 328
ASP C 316
 None
 1.40A 2rhmB-5g52C:
undetectable		 2rhmB-5g52C:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 5g52 VP3
(Deformed
wing
virus) 		4 / 5 PRO C  98
ILE C 314
ARG C 328
ASP C 316
 None
 1.43A 2rhmD-5g52C:
undetectable		 2rhmD-5g52C:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 5g52 VP3
(Deformed
wing
virus) 		3 / 3 LEU C  64
ARG C  67
ILE C  65
 None
 0.68A 2xn5B-5g52C:
undetectable		 2xn5B-5g52C:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5g52 VP2
(Deformed
wing
virus) 		5 / 12 ASP B  53
VAL B  52
SER B  48
SER B  43
TYR B  55
 None
 1.39A 2y00A-5g52B:
undetectable		 2y00A-5g52B:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5g52 VP2
(Deformed
wing
virus) 		5 / 12 ASP B  53
VAL B  52
SER B  48
SER B  43
TYR B  55
 None
 1.40A 2y00B-5g52B:
undetectable		 2y00B-5g52B:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5g52 VP1
VP3
(Deformed
wing
virus) 		5 / 10 GLU C  51
ARG C  61
ILE C  58
GLY A  98
MET C 113
 None
 1.44A 3adsA-5g52C:
undetectable		 3adsA-5g52C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5g52 VP3
(Deformed
wing
virus) 		3 / 3 ARG C  92
VAL C 331
THR C 345
 None
 0.73A 3cyxA-5g52C:
undetectable		 3cyxA-5g52C:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g52 VP1
(Deformed
wing
virus) 		4 / 5 LEU A  70
ARG A  88
ILE A  83
PHE A  84
 None
 1.27A 3ln1D-5g52A:
undetectable		 3ln1D-5g52A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 5g52 VP1
VP2
(Deformed
wing
virus) 		5 / 12 ILE B 207
HIS B 163
ALA B 174
LEU B  83
GLY A   1
 None
 1.05A 3ozwB-5g52B:
undetectable		 3ozwB-5g52B:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 5g52 VP1
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		5 / 12 GLN A  41
GLY A  90
GLN C 243
ASP A  89
MET A 242
 None
 1.28A 3t7sB-5g52A:
undetectable		 3t7sB-5g52A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 5g52 VP1
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		5 / 12 GLN A  41
GLY A  90
GLN C 243
ASP A  89
MET A 242
 None
 1.30A 3t7sD-5g52A:
undetectable		 3t7sD-5g52A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5g52 VP1
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		4 / 6 GLU C 392
ASP C 253
ASN A  85
GLU A  82
 None
 1.24A 3vywA-5g52C:
undetectable		 3vywA-5g52C:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 5g52 VP1
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		4 / 5 GLU C 392
ASP C 253
ASN A  85
GLU A  82
 None
 1.22A 3vywD-5g52C:
undetectable		 3vywD-5g52C:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 5g52 VP3
(Deformed
wing
virus) 		4 / 7 ALA C  85
PRO C  87
LEU C  83
LEU C 206
 None
 0.97A 4iomA-5g52C:
undetectable		 4iomA-5g52C:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5g52 VP1
VP3
(Deformed
wing
virus;
Deformed
wing
virus) 		4 / 8 LEU C 248
SER C 112
VAL A 237
GLY A 238
 None
 0.89A 4klrB-5g52C:
undetectable		 4klrB-5g52C:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5g52 VP1
VP2
(Deformed
wing
virus;
Deformed
wing
virus) 		3 / 3 ASP B 143
TRP B 115
SER A 189
 None
 1.06A 4lrhA-5g52B:
undetectable		 4lrhA-5g52B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5g52 VP2
(Deformed
wing
virus) 		3 / 3 TRP B 139
GLN B 160
THR B 138
 None
 0.50A 4m2xA-5g52B:
undetectable		 4m2xA-5g52B:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 5g52 VP1
VP2
(Deformed
wing
virus;
Deformed
wing
virus) 		3 / 3 LYS B 152
TRP A 236
GLN B 160
 None
 1.46A 4qzuC-5g52B:
undetectable		 4qzuC-5g52B:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5g52 VP1
VP3
(Deformed
wing
virus) 		4 / 8 PHE A  26
GLY A  27
TRP C 186
PHE C 114
 None
 0.72A 5flcB-5g52A:
undetectable		 5flcB-5g52A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5g52 VP1
VP3
(Deformed
wing
virus) 		4 / 8 PHE A  26
GLY A  27
TRP C 186
PHE C 114
 None
 0.73A 5flcF-5g52A:
undetectable		 5flcF-5g52A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 5g52 VP2
(Deformed
wing
virus) 		3 / 3 ILE B  58
MET B 119
ASP B  54
 None
 0.80A 5h2uA-5g52B:
undetectable		 5h2uA-5g52B:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5g52 VP2
(Deformed
wing
virus) 		4 / 4 ARG B 208
THR B 138
GLY B 157
PHE B 158
 None
 1.45A 5uunA-5g52B:
undetectable		 5uunA-5g52B:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5g52 VP3
(Deformed
wing
virus) 		4 / 8 ILE C 343
PHE C 311
LEU C 354
LEU C 309
 None
 0.87A 5y7pE-5g52C:
undetectable		 5y7pE-5g52C:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 5g52 VP3
(Deformed
wing
virus) 		5 / 9 VAL C 228
LEU C 121
ARG C  66
ALA C  85
SER C 204
 None
 0.92A 6c2mB-5g52C:
undetectable		 6c2mB-5g52C:
10.73