SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 HIS A 169
ILE A 168
ALA A 155
VAL A 209
 None
 1.03A 1hk1A-5g56A:
undetectable		 1hk1A-5g56A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 8 GLY A 134
GLU A 167
TRP A  69
HIS A  90
 None
 1.04A 1maaD-5g56A:
undetectable		 1maaD-5g56A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 GLU A 266
ARG A 436
LEU A 303
LEU A 296
 None
 1.16A 1n13B-5g56A:
undetectable
1n13C-5g56A:
undetectable		 1n13B-5g56A:
9.04
1n13C-5g56A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 ASN A 141
ASN A 135
ILE A 133
GLY A 134
 None
 1.08A 1oniD-5g56A:
undetectable
1oniF-5g56A:
undetectable		 1oniD-5g56A:
11.00
1oniF-5g56A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		3 / 3 GLU A 411
ASN A 507
TRP A 481
 MPD  A1747 (-3.0A)
MPD  A1747 (-3.2A)
None
 1.27A 1r15C-5g56A:
2.0		 1r15C-5g56A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.78A 1usqA-5g56A:
1.5		 1usqA-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.81A 1usqA-5g56A:
1.5		 1usqA-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.78A 1usqB-5g56A:
1.7		 1usqB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.80A 1usqB-5g56A:
1.7		 1usqB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.76A 1usqC-5g56A:
1.6		 1usqC-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.78A 1usqC-5g56A:
1.6		 1usqC-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.81A 1usqD-5g56A:
2.8		 1usqD-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.81A 1usqD-5g56A:
2.8		 1usqD-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.80A 1usqE-5g56A:
1.7		 1usqE-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.82A 1usqE-5g56A:
1.7		 1usqE-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 PRO A 177
THR A 261
GLY A 219
GLY A 221
GLN A 259
 None
 0.95A 1wg8A-5g56A:
undetectable		 1wg8A-5g56A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 PRO A 177
THR A 261
GLY A 219
GLY A 221
GLN A 259
 None
 0.99A 1wg8B-5g56A:
undetectable		 1wg8B-5g56A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.35A 2eimJ-5g56A:
undetectable		 2eimJ-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.34A 2eimW-5g56A:
undetectable		 2eimW-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 ASN A 439
ILE A 564
THR A 364
ALA A 363
PHE A 369
 None
 1.35A 2gl0A-5g56A:
undetectable
2gl0C-5g56A:
undetectable		 2gl0A-5g56A:
10.56
2gl0C-5g56A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 11 ASN A 439
ILE A 564
THR A 364
ALA A 363
PHE A 369
 None
 1.37A 2gl0D-5g56A:
undetectable
2gl0F-5g56A:
undetectable		 2gl0D-5g56A:
10.56
2gl0F-5g56A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_D_AZZD1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 10 ILE A 131
VAL A 196
MET A 192
ALA A 147
PHE A 150
 None
 1.21A 2jj8D-5g56A:
undetectable		 2jj8D-5g56A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.83A 2jkjA-5g56A:
3.0		 2jkjA-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.78A 2jkjA-5g56A:
3.0		 2jkjA-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.83A 2jkjB-5g56A:
3.6		 2jkjB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.79A 2jkjB-5g56A:
3.6		 2jkjB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.83A 2jkjC-5g56A:
1.7		 2jkjC-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.78A 2jkjC-5g56A:
1.7		 2jkjC-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.80A 2jklA-5g56A:
1.2		 2jklA-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.83A 2jklB-5g56A:
1.7		 2jklB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.79A 2jklB-5g56A:
1.7		 2jklB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.80A 2jklC-5g56A:
3.4		 2jklC-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.81A 2jklD-5g56A:
1.7		 2jklD-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 7 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.80A 2jklF-5g56A:
1.7		 2jklF-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ASN A 543
ASN A 544
ARG A 576
 None
 0.78A 2rlcA-5g56A:
undetectable		 2rlcA-5g56A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 ASN A 170
GLU A 171
HIS A 253
TYR A 255
GLU A 279
 None
MPD  A1746 (-2.7A)
None
MPD  A1746 (-3.8A)
None
 0.27A 2v3dA-5g56A:
14.5		 2v3dA-5g56A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.40A 3ag2J-5g56A:
undetectable		 3ag2J-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.46A 3ag4J-5g56A:
undetectable		 3ag4J-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 TYR A 443
GLY A 493
GLY A 491
ASP A 293
TRP A 258
 None
 1.27A 3dlcA-5g56A:
undetectable		 3dlcA-5g56A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A 292
LEU A 331
LEU A 337
GLY A  85
LEU A  84
 None
 1.37A 3hm1B-5g56A:
undetectable		 3hm1B-5g56A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 10 GLY A 372
ALA A 363
VAL A 437
GLY A 566
ILE A 516
 None
 1.01A 3nu6B-5g56A:
undetectable		 3nu6B-5g56A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 10 GLY A 372
ALA A 363
VAL A 437
GLY A 566
ILE A 516
 None
 1.03A 3nu9B-5g56A:
undetectable		 3nu9B-5g56A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 GLU A 299
LEU A 296
GLN A 259
GLY A 257
 None
 1.30A 3pp1A-5g56A:
undetectable		 3pp1A-5g56A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 ASP A 607
ARG A 531
ILE A 623
THR A 605
ALA A 653
 None
 1.26A 3ua1A-5g56A:
undetectable		 3ua1A-5g56A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		3 / 3 GLN A 487
THR A 485
ASN A 444
 None
 0.80A 3v4tE-5g56A:
0.1		 3v4tE-5g56A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 9 ILE A 511
GLN A 495
LEU A 497
VAL A 459
LEU A 445
 None
 1.19A 4g1bC-5g56A:
2.4		 4g1bC-5g56A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 372
ALA A 363
VAL A 437
GLY A 566
ILE A 516
 None
 1.05A 4njvD-5g56A:
undetectable		 4njvD-5g56A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 8 PHE A 150
THR A  67
LEU A  91
LEU A 129
 None
 0.73A 5hs1A-5g56A:
undetectable		 5hs1A-5g56A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 9 GLY A 372
ALA A 363
VAL A 437
GLY A 566
ILE A 516
 None
 0.99A 5kr0B-5g56A:
undetectable		 5kr0B-5g56A:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 8 GLY A 372
ALA A 363
VAL A 437
GLY A 566
ILE A 516
 None
 1.12A 5kr1B-5g56A:
undetectable		 5kr1B-5g56A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 VAL A 711
ASN A 670
ASP A 663
LEU A 662
 None
 0.89A 5m0iB-5g56A:
undetectable		 5m0iB-5g56A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.33A 5w97J-5g56A:
undetectable		 5w97J-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.42A 5wauJ-5g56A:
undetectable		 5wauJ-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		5 / 12 LEU A 292
GLY A 283
SER A 329
GLY A 290
GLY A 291
 None
 0.97A 5wyqB-5g56A:
undetectable		 5wyqB-5g56A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 4 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.40A 5x19W-5g56A:
0.0		 5x19W-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		3 / 3 TYR A 197
ARG A 198
THR A 202
 None
 0.72A 5z84J-5g56A:
undetectable		 5z84J-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.29A 5z86J-5g56A:
undetectable		 5z86J-5g56A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 6 LEU A 308
ALA A  88
LEU A 210
SER A 306
 None
 0.97A 6f88B-5g56A:
undetectable		 6f88B-5g56A:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g56 CARBOHYDRATE BINDING
FAMILY 6
(Ruminiclostridiu
m
thermocellum) 		4 / 5 TYR A  75
ARG A 121
THR A 122
LEU A 127
 None
 1.28A 6nknW-5g56A:
undetectable		 6nknW-5g56A:
4.71