SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5g5d CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 SER B 159
SER B 158
THR B 157
ASN B 107
 None
 0.89A 2i91A-5g5dB:
undetectable		 2i91A-5g5dB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5g5d CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 SER B 159
SER B 158
THR B 157
ASN B 107
 None
 0.90A 2i91B-5g5dB:
undetectable		 2i91B-5g5dB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5g5d CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 TYR B 161
MET B  98
LEU B  74
ASP B  75
 None
 1.35A 3lslA-5g5dB:
undetectable
3lslD-5g5dB:
undetectable		 3lslA-5g5dB:
21.88
3lslD-5g5dB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5g5d CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 TYR B 161
MET B  98
LEU B  74
ASP B  75
 None
 1.38A 3lslA-5g5dB:
undetectable
3lslD-5g5dB:
undetectable		 3lslA-5g5dB:
21.88
3lslD-5g5dB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5g5d CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 6 TYR B 161
MET B  98
LEU B  74
ASP B  75
 None
 1.41A 3lslG-5g5dB:
undetectable		 3lslG-5g5dB:
21.88