SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 12 LEU A 103
PHE A 197
GLY A 157
TYR A 158
PHE A 166
 None
None
PEG  A1226 (-3.4A)
None
None
 1.15A 1brpA-5g5fA:
undetectable		 1brpA-5g5fA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 12 LYS A  27
ILE A 161
ALA A 162
PRO A  87
LEU A  86
 None
None
None
PEG  A1226 (-3.4A)
None
 1.17A 3a51E-5g5fA:
undetectable		 3a51E-5g5fA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S68_A_SAMA228_0
(CATECHOL
O-METHYLTRANSFERASE)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 10 GLU A  36
GLY A  10
SER A  42
GLU A  35
SER A  14
 None
None
None
None
GSH  A1222 (-2.5A)
 1.39A 3s68A-5g5fA:
undetectable		 3s68A-5g5fA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		4 / 6 ARG A  19
PRO A  56
GLU A  67
SER A  68
 None
GSH  A1222 (-4.3A)
GSH  A1222 (-3.1A)
GSH  A1222 (-2.4A)
 0.36A 3vlnA-5g5fA:
23.7		 3vlnA-5g5fA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		4 / 8 SER A 133
LEU A 134
PHE A 163
TYR A 102
 None
 1.15A 4j7uD-5g5fA:
undetectable		 4j7uD-5g5fA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 9 ALA A 194
ASP A 160
GLY A 164
LEU A 167
LEU A 182
 None
 1.22A 5dqfA-5g5fA:
2.9		 5dqfA-5g5fA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 10 ILE A  71
LEU A   8
VAL A 206
ILE A 161
PRO A 208
 None
 1.16A 5ienB-5g5fA:
undetectable		 5ienB-5g5fA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		5 / 12 ILE A 137
PHE A 163
ALA A 194
PHE A 197
LEU A 170
 None
 1.03A 6dwnD-5g5fA:
undetectable		 6dwnD-5g5fA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE
(Mangifera
indica) 		4 / 7 TYR A  74
HIS A  60
LEU A  24
VAL A  29
 None
 1.20A 6g2pA-5g5fA:
undetectable		 6g2pA-5g5fA:
21.05