SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g5n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A  53
VAL A  75
TRP A  57
 None
 0.79A 1av2C-5g5nA:
undetectable
1av2D-5g5nA:
undetectable		 1av2C-5g5nA:
5.15
1av2D-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A 180
VAL A 204
TRP A 209
 None
 0.86A 1grmA-5g5nA:
undetectable		 1grmA-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A 180
VAL A 204
TRP A 209
 None
 0.86A 1grmB-5g5nA:
undetectable		 1grmB-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 7 LEU A 266
THR A 120
MET A 123
TRP A 126
 None
GOL  A1374 (-3.1A)
GOL  A1374 ( 4.9A)
MMC  A1379 ( 3.4A)
 1.24A 1kglA-5g5nA:
undetectable		 1kglA-5g5nA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A 180
VAL A 204
TRP A 209
 None
 0.94A 1magA-5g5nA:
undetectable		 1magA-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A 180
VAL A 204
TRP A 209
 None
 0.94A 1magB-5g5nA:
undetectable		 1magB-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A  53
VAL A  75
TRP A  57
 None
 0.77A 1w5uC-5g5nA:
undetectable
1w5uD-5g5nA:
undetectable		 1w5uC-5g5nA:
5.15
1w5uD-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 7 GLY A  70
PRO A  51
TYR A  55
THR A  30
 None
 1.18A 2aouB-5g5nA:
undetectable		 2aouB-5g5nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 7 TYR A 255
GLY A 321
THR A 323
TYR A 295
 None
 0.93A 2g70A-5g5nA:
undetectable		 2g70A-5g5nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 7 TYR A 255
GLY A 321
THR A 323
TYR A 295
 None
 0.89A 2g70B-5g5nA:
undetectable		 2g70B-5g5nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 TRP A  57
ALA A  53
VAL A  75
 None
 0.82A 2izqA-5g5nA:
undetectable
2izqB-5g5nA:
undetectable		 2izqA-5g5nA:
5.15
2izqB-5g5nA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 9 LEU A  49
ILE A  86
ILE A  83
PRO A  37
ILE A  68
 None
 1.18A 3d1yB-5g5nA:
undetectable		 3d1yB-5g5nA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 ILE A 179
ALA A 145
VAL A 165
ILE A 132
CYH A 127
 None
 0.99A 3e00A-5g5nA:
undetectable		 3e00A-5g5nA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 10 ILE A 179
ALA A 145
VAL A 165
ILE A 132
CYH A 127
 None
 0.89A 3falA-5g5nA:
undetectable		 3falA-5g5nA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 GLY A 324
GLY A 318
LEU A 316
VAL A 350
GLN A 370
 None
 1.28A 3fzgA-5g5nA:
undetectable		 3fzgA-5g5nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 10 ALA A  40
VAL A  60
ILE A  98
LEU A 125
ILE A  62
 None
 1.00A 3jw3A-5g5nA:
undetectable		 3jw3A-5g5nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 9 ALA A  40
VAL A  60
ILE A  98
LEU A 125
ILE A  62
 None
 0.99A 3jw3B-5g5nA:
undetectable		 3jw3B-5g5nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A  53
VAL A  75
TRP A  57
 None
 0.81A 3l8lA-5g5nA:
undetectable
3l8lB-5g5nA:
undetectable		 3l8lA-5g5nA:
5.15
3l8lB-5g5nA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ALA A  53
VAL A  75
TRP A  57
 None
 0.73A 3l8lC-5g5nA:
undetectable
3l8lD-5g5nA:
undetectable		 3l8lC-5g5nA:
5.15
3l8lD-5g5nA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 8 TYR A 148
ILE A 147
VAL A 185
ILE A 132
 GOL  A1374 ( 4.6A)
None
None
None
 0.82A 3p4wC-5g5nA:
undetectable		 3p4wC-5g5nA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 8 GLY A 144
GLN A 122
PHE A 115
SER A 116
 None
 0.90A 4ws1A-5g5nA:
undetectable		 4ws1A-5g5nA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 LEU A 224
SER A 191
ASN A 214
PHE A 245
THR A 210
 None
 1.43A 5d0yA-5g5nA:
undetectable		 5d0yA-5g5nA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 LEU A 224
SER A 191
ASN A 214
PHE A 245
THR A 246
 None
 1.36A 5d0yA-5g5nA:
undetectable		 5d0yA-5g5nA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 LEU A 224
SER A 191
ASN A 214
PHE A 245
THR A 210
 None
 1.43A 5d0yB-5g5nA:
undetectable		 5d0yB-5g5nA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 12 LEU A 224
SER A 191
ASN A 214
PHE A 245
THR A 246
 None
 1.37A 5d0yB-5g5nA:
undetectable		 5d0yB-5g5nA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 9 LEU A  49
ILE A  86
ILE A  83
PRO A  37
ILE A  68
 None
 1.12A 5kqxB-5g5nA:
undetectable		 5kqxB-5g5nA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 9 ALA A 180
ILE A 134
ILE A 132
ILE A  86
ALA A 145
 None
 0.94A 5nunA-5g5nA:
undetectable		 5nunA-5g5nA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		5 / 9 LEU A 101
LEU A  49
ILE A  62
LEU A 125
ALA A  40
 None
 1.33A 5og9A-5g5nA:
undetectable		 5og9A-5g5nA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 7 GLN A 227
GLY A 228
ILE A 271
GLN A 199
 None
 1.11A 5vlmC-5g5nA:
undetectable		 5vlmC-5g5nA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 8 GLN A 227
GLY A 228
ILE A 271
GLN A 199
 None
 0.97A 5vlmD-5g5nA:
undetectable		 5vlmD-5g5nA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		4 / 8 ASN A 291
SER A 292
GLN A 293
ALA A 315
 None
 0.97A 5xu8A-5g5nA:
undetectable		 5xu8A-5g5nA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ASN A  59
PRO A  82
GLN A 122
 None
 0.79A 6jnhA-5g5nA:
undetectable		 6jnhA-5g5nA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN
(Snake
atadenovirus
A) 		3 / 3 ASN A  59
PRO A  82
GLN A 122
 None
 0.76A 6jogA-5g5nA:
undetectable		 6jogA-5g5nA:
18.93