SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  30
ASP A 111
LEU A 110
LEU A  59
 None
 1.02A 1e7cA-5g5uA:
undetectable		 1e7cA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 181
VAL A 215
TRP A 226
 None
 0.84A 1kqeA-5g5uA:
undetectable
1kqeE-5g5uA:
undetectable		 1kqeA-5g5uA:
3.30
1kqeE-5g5uA:
3.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 181
VAL A 215
TRP A 226
 None
 0.85A 1kqeB-5g5uA:
undetectable
1kqeD-5g5uA:
undetectable		 1kqeB-5g5uA:
3.30
1kqeD-5g5uA:
3.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 226
ALA A 181
VAL A 215
 None
 0.85A 1kqeB-5g5uA:
undetectable
1kqeD-5g5uA:
undetectable		 1kqeB-5g5uA:
3.30
1kqeD-5g5uA:
3.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 226
ALA A 181
VAL A 215
 None
 0.85A 1kqeA-5g5uA:
undetectable
1kqeE-5g5uA:
undetectable		 1kqeA-5g5uA:
3.30
1kqeE-5g5uA:
3.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 208
ALA A 169
SER A 190
LEU A 192
 None
 0.77A 2bxgA-5g5uA:
undetectable		 2bxgA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  59
LEU A  14
ILE A  53
ALA A  52
 None
 0.70A 2i2zA-5g5uA:
undetectable		 2i2zA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 6 PRO A 164
HIS A 162
ASP A 245
ASP A 244
 None
 1.37A 2lh8A-5g5uA:
undetectable		 2lh8A-5g5uA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 8 MET A   1
LEU A 291
PRO A 296
GLY A 272
 None
 1.11A 2qd5B-5g5uA:
undetectable		 2qd5B-5g5uA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 212
VAL A 215
LEU A 235
GLU A 234
SER A 223
 None
 1.29A 3apvA-5g5uA:
undetectable		 3apvA-5g5uA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 212
VAL A 215
LEU A 235
GLU A 234
SER A 223
 None
 1.31A 3apvB-5g5uA:
undetectable		 3apvB-5g5uA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  59
ARG A  19
LEU A  22
ALA A  49
 None
 1.14A 3b9mA-5g5uA:
undetectable		 3b9mA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  59
ARG A  19
LEU A  22
ALA A  52
 None
 0.99A 3b9mA-5g5uA:
undetectable		 3b9mA-5g5uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 299
ARG A 301
ALA A 204
PHE A 242
LEU A 112
 None
 1.15A 3gwuA-5g5uA:
undetectable		 3gwuA-5g5uA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 7 MET A   1
LEU A 291
PRO A 296
GLY A 272
 None
 1.10A 3hcnA-5g5uA:
undetectable		 3hcnA-5g5uA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 144
ASP A 191
GLY A 135
GLU A 134
 None
 0.95A 5bs8A-5g5uA:
undetectable
5bs8B-5g5uA:
undetectable
5bs8C-5g5uA:
undetectable		 5bs8A-5g5uA:
23.02
5bs8B-5g5uA:
23.30
5bs8C-5g5uA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 144
ASP A 191
GLY A 135
GLU A 134
 None
 0.95A 5btdA-5g5uA:
undetectable
5btdB-5g5uA:
undetectable
5btdC-5g5uA:
0.7		 5btdA-5g5uA:
23.02
5btdB-5g5uA:
23.30
5btdC-5g5uA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 144
ASP A 191
GLY A 135
GLU A 134
 None
 0.95A 5btdA-5g5uA:
undetectable
5btdC-5g5uA:
0.7
5btdD-5g5uA:
undetectable		 5btdA-5g5uA:
23.02
5btdC-5g5uA:
23.02
5btdD-5g5uA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  62
PHE A 114
LYS A 161
HIS A 162
MET A 206
 None
 0.84A 5m6gA-5g5uA:
22.0		 5m6gA-5g5uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g5u BETA-HEXOSAMINIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 139
LEU A 143
PHE A 147
 None
 0.77A 6nknP-5g5uA:
undetectable		 6nknP-5g5uA:
20.06