SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_C_DVAC6_0 (GRAMICIDIN A)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 429 VAL A 380 TRP A 384	None None DQR A 544 (-4.1A)	0.85A	1av2C-5g5zA: undetectable 1av2D-5g5zA: undetectable	1av2C-5g5zA: 2.85 1av2D-5g5zA: 2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_A_IPBA600_0 (ODORANT-BINDING PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 6	VAL A 341 MET A 460 ASN A 180 ILE A 452	None	0.96A	1e06A-5g5zA: undetectable	1e06A-5g5zA: 17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FXV_B_PNNB1001_0 (PENICILLIN ACYLASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PHE A 227 SER A 231 PHE A 238 ALA A 291	None	1.24A	1fxvA-5g5zA: undetectable 1fxvB-5g5zA: undetectable	1fxvA-5g5zA: 17.72 1fxvB-5g5zA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KI3_A_PE2A1_1 (THYMIDINE KINASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 479 ILE A 525 TYR A 522 MET A 471 GLU A 483	None	1.41A	1ki3A-5g5zA: undetectable	1ki3A-5g5zA: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2201_1 (PROTEIN (METHIONINE REPRESSOR))	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	HIS A 340 ALA A 243 PHE A 242 GLY A 246	None	1.31A	1mj2B-5g5zA: undetectable	1mj2B-5g5zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC1200_1 (PROTEIN (METHIONINE REPRESSOR))	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	HIS A 340 ALA A 243 PHE A 242 GLY A 246	None	1.38A	1mj2D-5g5zA: undetectable	1mj2D-5g5zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_A_SAMA199_1 (METHIONINE REPRESSOR)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	HIS A 340 ALA A 243 PHE A 242 GLY A 246	None	1.33A	1mjoB-5g5zA: undetectable	1mjoB-5g5zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_B_SAMB200_0 (METHIONINE REPRESSOR)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	HIS A 340 ALA A 243 PHE A 242 GLY A 246	None	1.29A	1mjoA-5g5zA: undetectable	1mjoA-5g5zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_D_SAMD200_1 (METHIONINE REPRESSOR)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	HIS A 340 ALA A 243 PHE A 242 GLY A 246	None	1.33A	1mjoD-5g5zA: undetectable	1mjoD-5g5zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_A_DVAA6_0 (GRAMICIDIN C)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 429 VAL A 380 TRP A 384	None None DQR A 544 (-4.1A)	0.81A	1nt6A-5g5zA: undetectable	1nt6A-5g5zA: 2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_B_DVAB6_0 (GRAMICIDIN C)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 429 VAL A 380 TRP A 384	None None DQR A 544 (-4.1A)	0.81A	1nt6B-5g5zA: undetectable	1nt6B-5g5zA: 2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WSV_B_THHB4001_0 (AMINOMETHYLTRANSFERA SE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 281 ILE A 278 VAL A 275 PHE A 312 LEU A 204	None	1.32A	1wsvB-5g5zA: undetectable	1wsvB-5g5zA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ASP A 109 PHE A 89 ARG A 93	None	0.74A	2a3aA-5g5zA: undetectable	2a3aA-5g5zA: 24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_D_SAMD301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	LYS A 239 ASP A 113 ASP A 251	None	0.74A	2br4D-5g5zA: undetectable	2br4D-5g5zA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HMA_A_SAMA375_0 (PROBABLE TRNA (5-METHYLAMINOMETHYL -2-THIOURIDYLATE)-ME THYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 11	GLY A 303 ASP A 188 ASN A 186 THR A 320 GLY A 321	None	1.45A	2hmaA-5g5zA: undetectable	2hmaA-5g5zA: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_B_DVAB6_0 (GRAMICIDIN D)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	TRP A 384 ALA A 429 VAL A 380	DQR A 544 (-4.1A) None None	0.81A	2izqA-5g5zA: undetectable 2izqB-5g5zA: undetectable	2izqA-5g5zA: 2.85 2izqB-5g5zA: 2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_D_ACTD37_0 (GCN4 LEUCINE ZIPPER)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	LYS A 526 ARG A 468 VAL A 469	None	0.87A	2r2vC-5g5zA: undetectable 2r2vD-5g5zA: undetectable	2r2vC-5g5zA: 4.94 2r2vD-5g5zA: 4.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RCT_A_RTLA140_1 (RETINOL-BINDING PROTEIN II, CELLULAR)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	GLN A 378 THR A 439 TRP A 384	None None DQR A 544 (-4.1A)	1.13A	2rctA-5g5zA: undetectable	2rctA-5g5zA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_G_ASDG1224_1 (GLUTATHIONE S-TRANSFERASE A3)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PHE A 245 LEU A 281 LEU A 332 ALA A 244	None	1.00A	2vcvG-5g5zA: undetectable	2vcvG-5g5zA: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_1 (NON-STRUCTURAL PROTEIN 5)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	SER A 112 HIS A 253 ASP A 237	None	0.74A	2wa2B-5g5zA: undetectable	2wa2B-5g5zA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAD_F_GCSF710_1 (N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE TEICOPLANIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 8	HIS A 294 ASP A 288 SER A 228 ILE A 225	None	0.93A	2xadB-5g5zA: undetectable	2xadB-5g5zA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAD_H_GCSH710_1 (N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE TEICOPLANIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 8	HIS A 294 ASP A 288 SER A 228 ILE A 225	None	0.93A	2xadD-5g5zA: undetectable	2xadD-5g5zA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_B_VD3B2001_1 (VITAMIN D HYDROXYLASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 11	THR A 76 LEU A 49 ILE A 80 THR A 53 PRO A 427	None	1.36A	3a50B-5g5zA: undetectable	3a50B-5g5zA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AF0_A_PAUA314_0 (PANTOTHENATE KINASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 8	ASP A 267 LEU A 514 TYR A 510 TYR A 522	CA A 546 (-3.0A) None None None	1.05A	3af0A-5g5zA: undetectable	3af0A-5g5zA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B0W_A_DGXA1_1 (NUCLEAR RECEPTOR ROR-GAMMA)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 241 MET A 182 ALA A 183 VAL A 328 LEU A 449	None	1.10A	3b0wA-5g5zA: undetectable	3b0wA-5g5zA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_A_DVAA6_0 (GRAMICIDIN D)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 429 VAL A 380 TRP A 384	None None DQR A 544 (-4.1A)	0.84A	3l8lA-5g5zA: undetectable 3l8lB-5g5zA: undetectable	3l8lA-5g5zA: 2.85 3l8lB-5g5zA: 3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N3I_A_ROCA201_1 (PROTEASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	ASP A 352 GLY A 110 ALA A 111 ASP A 115 ILE A 125	None	1.11A	3n3iA-5g5zA: undetectable	3n3iA-5g5zA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 449 GLY A 348 GLY A 170 SER A 175 ALA A 429	None	1.05A	3ou6A-5g5zA: undetectable	3ou6A-5g5zA: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 449 GLY A 348 GLY A 170 SER A 175 ALA A 429	None	1.05A	3ou6B-5g5zA: undetectable	3ou6B-5g5zA: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_B_SAMB300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 449 GLY A 348 GLY A 170 SER A 175 ALA A 429	None	1.03A	3ou7B-5g5zA: undetectable	3ou7B-5g5zA: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_A_PFLA319_1 (GLR4197 PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PRO A 103 ILE A 97 THR A 357 ILE A 125	None	0.97A	3p50A-5g5zA: undetectable	3p50A-5g5zA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_B_PFLB319_1 (GLR4197 PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PRO A 103 ILE A 97 THR A 357 ILE A 125	None	0.97A	3p50B-5g5zA: undetectable	3p50B-5g5zA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_C_PFLC319_1 (GLR4197 PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PRO A 103 ILE A 97 THR A 357 ILE A 125	None	0.97A	3p50C-5g5zA: undetectable	3p50C-5g5zA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_D_PFLD320_1 (GLR4197 PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PRO A 103 ILE A 97 THR A 357 ILE A 125	None	0.97A	3p50D-5g5zA: undetectable	3p50D-5g5zA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P50_E_PFLE319_1 (GLR4197 PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PRO A 103 ILE A 97 THR A 357 ILE A 125	None	0.96A	3p50E-5g5zA: undetectable	3p50E-5g5zA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QL3_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 490 ASP A 249 ILE A 498 TYR A 510 THR A 265	None	1.23A	3ql3A-5g5zA: undetectable	3ql3A-5g5zA: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_B_SAMB801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 11	GLY A 321 ASP A 327 VAL A 328 ASN A 318 LEU A 451	None None None DQR A 544 (-3.1A) None	1.14A	3v8vB-5g5zA: undetectable	3v8vB-5g5zA: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG305_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ASP A 181 ARG A 494 LYS A 239	None	1.23A	3wipG-5g5zA: undetectable	3wipG-5g5zA: 17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZT_A_SAMA1472_1 (METHYLTRANSFERASE WBDD)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	GLN A 70 ASP A 389 GLN A 392	None	0.90A	4aztA-5g5zA: undetectable	4aztA-5g5zA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B17_A_SAMA1358_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	GLY A 110 GLY A 426 GLY A 425 ASP A 109 ASP A 115	None	0.96A	4b17A-5g5zA: undetectable	4b17A-5g5zA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJE_B_C2FB302_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	GLU A 515 MET A 486 ASP A 267 ASN A 268 SER A 520	None None CA A 546 (-3.0A) CA A 546 (-2.9A) None	1.45A	4djeB-5g5zA: undetectable	4djeB-5g5zA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJF_B_C2FB300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	GLU A 515 MET A 486 ASP A 267 ASN A 268 SER A 520	None None CA A 546 (-3.0A) CA A 546 (-2.9A) None	1.47A	4djfB-5g5zA: undetectable	4djfB-5g5zA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	PHE A 349 ILE A 142 TYR A 374 PRO A 164	None	1.16A	4g5jA-5g5zA: undetectable	4g5jA-5g5zA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G8Z_X_TOPX301_1 (DIHYDROFOLATE REDUCTASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 10	ILE A 126 ALA A 120 LEU A 116 PRO A 164 ILE A 356	None	1.18A	4g8zX-5g5zA: undetectable	4g8zX-5g5zA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOT_A_CE3A205_1 (UNCHARACTERIZED PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	GLY A 234 ASN A 180 ILE A 230 PHE A 238 TYR A 299	None	1.30A	4kotA-5g5zA: undetectable	4kotA-5g5zA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOT_A_CE3A205_1 (UNCHARACTERIZED PROTEIN)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	PHE A 242 GLY A 234 ASN A 180 ILE A 230 PHE A 238	None	1.36A	4kotA-5g5zA: undetectable	4kotA-5g5zA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYK_B_IMNB300_1 (LACTOYLGLUTATHIONE LYASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	PHE A 277 LEU A 241 GLY A 285 LYS A 284 LEU A 208	None	1.19A	4kykA-5g5zA: undetectable 4kykB-5g5zA: undetectable	4kykA-5g5zA: 16.43 4kykB-5g5zA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PBH_A_BEZA401_0 (TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 278 ALA A 244 LEU A 281 LEU A 204 PHE A 245	None	1.44A	4pbhA-5g5zA: undetectable	4pbhA-5g5zA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	ASP A 531 LYS A 526 LEU A 254	None	1.06A	4ptjA-5g5zA: undetectable	4ptjA-5g5zA: 15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2O_A_ACTA1728_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 5	GLN A 392 THR A 386 ASP A 389 ASN A 394	None	1.47A	5b2oA-5g5zA: 0.0	5b2oA-5g5zA: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2P_A_ACTA1728_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 5	GLN A 392 THR A 386 ASP A 389 ASN A 394	None	1.47A	5b2pA-5g5zA: 0.5	5b2pA-5g5zA: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2Q_A_ACTA1729_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 5	GLN A 392 THR A 386 ASP A 389 ASN A 394	None	1.48A	5b2qA-5g5zA: 0.0	5b2qA-5g5zA: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_2 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	GLU A 75 TRP A 369 ASN A 138	None	1.15A	5dv4A-5g5zA: undetectable	5dv4A-5g5zA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGV_A_ZITA404_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 4	ASN A 180 ILE A 247 TYR A 271 PHE A 277	None	1.07A	5igvA-5g5zA: undetectable	5igvA-5g5zA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JLC_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	5 / 12	ALA A 90 ILE A 142 TYR A 374 PHE A 349 THR A 154	None	1.30A	5jlcA-5g5zA: undetectable	5jlcA-5g5zA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M0I_B_ACTB303_0 (SWI5-DEPENDENT HO EXPRESSION PROTEIN 2)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 5	VAL A 256 ASN A 250 ASP A 252 LEU A 254	None	1.31A	5m0iB-5g5zA: undetectable	5m0iB-5g5zA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6I0Y_A_TRPA3001_0 (23S RIBOSOMAL RNA TRYPTOPHANASE OPERON LEADER PEPTIDE)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	3 / 3	TRP A 184 ILE A 185 ASP A 327	None	0.84A	6i0y7-5g5zA: undetectable	6i0y7-5g5zA: 5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_B_AM2B301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 8	TRP A 314 HIS A 177 GLU A 167 GLU A 423	DQR A 544 (-4.1A) DQR A 544 (-4.7A) DQR A 544 (-2.8A) DQR A 544 (-2.8A)	1.14A	6mn4B-5g5zA: undetectable	6mn4B-5g5zA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_F_AM2F301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5g5z	ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN (Streptococcus pneumoniae)	4 / 7	TRP A 314 HIS A 177 GLU A 167 GLU A 423	DQR A 544 (-4.1A) DQR A 544 (-4.7A) DQR A 544 (-2.8A) DQR A 544 (-2.8A)	1.29A	6mn4F-5g5zA: undetectable	6mn4F-5g5zA: 19.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_C_DVAC6_0","GRAMICIDIN A","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ALA A 429;VAL A 380;TRP A 384","None;None;DQR A 544 (-4.1A)","0.85A","1av2C-5g5zA:undetectable;1av2D-5g5zA:undetectable","1av2C-5g5zA:2.85;1av2D-5g5zA:2.85"],["1E06_A_IPBA600_0","ODORANT-BINDING PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"VAL A 341;MET A 460;ASN A 180;ILE A 452","None","0.96A","1e06A-5g5zA:undetectable","1e06A-5g5zA:17.92"],["1FXV_B_PNNB1001_0","PENICILLIN ACYLASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PHE A 227;SER A 231;PHE A 238;ALA A 291","None","1.24A","1fxvA-5g5zA:undetectable;1fxvB-5g5zA:undetectable","1fxvA-5g5zA:17.72;1fxvB-5g5zA:21.82"],["1KI3_A_PE2A1_1","THYMIDINE KINASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ILE A 479;ILE A 525;TYR A 522;MET A 471;GLU A 483","None","1.41A","1ki3A-5g5zA:undetectable","1ki3A-5g5zA:18.71"],["1MJ2_A_SAMA2201_1","PROTEIN (METHIONINE REPRESSOR)","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 340;ALA A 243;PHE A 242;GLY A 246","None","1.31A","1mj2B-5g5zA:undetectable","1mj2B-5g5zA:15.44"],["1MJ2_C_SAMC1200_1","PROTEIN (METHIONINE REPRESSOR)","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 340;ALA A 243;PHE A 242;GLY A 246","None","1.38A","1mj2D-5g5zA:undetectable","1mj2D-5g5zA:15.44"],["1MJO_A_SAMA199_1","METHIONINE REPRESSOR","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 340;ALA A 243;PHE A 242;GLY A 246","None","1.33A","1mjoB-5g5zA:undetectable","1mjoB-5g5zA:15.44"],["1MJO_B_SAMB200_0","METHIONINE REPRESSOR","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 340;ALA A 243;PHE A 242;GLY A 246","None","1.29A","1mjoA-5g5zA:undetectable","1mjoA-5g5zA:15.44"],["1MJO_D_SAMD200_1","METHIONINE REPRESSOR","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 340;ALA A 243;PHE A 242;GLY A 246","None","1.33A","1mjoD-5g5zA:undetectable","1mjoD-5g5zA:15.44"],["1NT6_A_DVAA6_0","GRAMICIDIN C","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ALA A 429;VAL A 380;TRP A 384","None;None;DQR A 544 (-4.1A)","0.81A","1nt6A-5g5zA:undetectable","1nt6A-5g5zA:2.68"],["1NT6_B_DVAB6_0","GRAMICIDIN C","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ALA A 429;VAL A 380;TRP A 384","None;None;DQR A 544 (-4.1A)","0.81A","1nt6B-5g5zA:undetectable","1nt6B-5g5zA:2.68"],["1WSV_B_THHB4001_0","AMINOMETHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"LEU A 281;ILE A 278;VAL A 275;PHE A 312;LEU A 204","None","1.32A","1wsvB-5g5zA:undetectable","1wsvB-5g5zA:21.88"],["2A3A_A_TEPA1436_1","CHITINASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ASP A 109;PHE A  89;ARG A  93","None","0.74A","2a3aA-5g5zA:undetectable","2a3aA-5g5zA:24.64"],["2BR4_D_SAMD301_1","CEPHALOSPORIN HYDROXYLASE CMCI","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"LYS A 239;ASP A 113;ASP A 251","None","0.74A","2br4D-5g5zA:undetectable","2br4D-5g5zA:18.26"],["2HMA_A_SAMA375_0","PROBABLE TRNA (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLY A 303;ASP A 188;ASN A 186;THR A 320;GLY A 321","None","1.45A","2hmaA-5g5zA:undetectable","2hmaA-5g5zA:22.18"],["2IZQ_B_DVAB6_0","GRAMICIDIN D","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"TRP A 384;ALA A 429;VAL A 380","DQR A 544 (-4.1A);None;None","0.81A","2izqA-5g5zA:undetectable;2izqB-5g5zA:undetectable","2izqA-5g5zA:2.85;2izqB-5g5zA:2.85"],["2R2V_D_ACTD37_0","GCN4 LEUCINE ZIPPER","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"LYS A 526;ARG A 468;VAL A 469","None","0.87A","2r2vC-5g5zA:undetectable;2r2vD-5g5zA:undetectable","2r2vC-5g5zA:4.94;2r2vD-5g5zA:4.94"],["2RCT_A_RTLA140_1","RETINOL-BINDING PROTEIN II, CELLULAR","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"GLN A 378;THR A 439;TRP A 384","None;None;DQR A 544 (-4.1A)","1.13A","2rctA-5g5zA:undetectable","2rctA-5g5zA:13.79"],["2VCV_G_ASDG1224_1","GLUTATHIONE S-TRANSFERASE A3","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PHE A 245;LEU A 281;LEU A 332;ALA A 244","None","1.00A","2vcvG-5g5zA:undetectable","2vcvG-5g5zA:17.66"],["2WA2_B_SAMB1267_1","NON-STRUCTURAL PROTEIN 5","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"SER A 112;HIS A 253;ASP A 237","None","0.74A","2wa2B-5g5zA:undetectable","2wa2B-5g5zA:17.43"],["2XAD_F_GCSF710_1","N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE;TEICOPLANIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 294;ASP A 288;SER A 228;ILE A 225","None","0.93A","2xadB-5g5zA:undetectable","2xadB-5g5zA:20.00"],["2XAD_H_GCSH710_1","N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE;TEICOPLANIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"HIS A 294;ASP A 288;SER A 228;ILE A 225","None","0.93A","2xadD-5g5zA:undetectable","2xadD-5g5zA:20.00"],["3A50_B_VD3B2001_1","VITAMIN D HYDROXYLASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"THR A  76;LEU A  49;ILE A  80;THR A  53;PRO A 427","None","1.36A","3a50B-5g5zA:undetectable","3a50B-5g5zA:19.54"],["3AF0_A_PAUA314_0","PANTOTHENATE KINASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"ASP A 267;LEU A 514;TYR A 510;TYR A 522"," CA A 546 (-3.0A);None;None;None","1.05A","3af0A-5g5zA:undetectable","3af0A-5g5zA:19.92"],["3B0W_A_DGXA1_1","NUCLEAR RECEPTOR ROR-GAMMA","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"LEU A 241;MET A 182;ALA A 183;VAL A 328;LEU A 449","None","1.10A","3b0wA-5g5zA:undetectable","3b0wA-5g5zA:19.75"],["3L8L_A_DVAA6_0","GRAMICIDIN D","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ALA A 429;VAL A 380;TRP A 384","None;None;DQR A 544 (-4.1A)","0.84A","3l8lA-5g5zA:undetectable;3l8lB-5g5zA:undetectable","3l8lA-5g5zA:2.85;3l8lB-5g5zA:3.09"],["3N3I_A_ROCA201_1","PROTEASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ASP A 352;GLY A 110;ALA A 111;ASP A 115;ILE A 125","None","1.11A","3n3iA-5g5zA:undetectable","3n3iA-5g5zA:17.04"],["3OU6_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"LEU A 449;GLY A 348;GLY A 170;SER A 175;ALA A 429","None","1.05A","3ou6A-5g5zA:undetectable","3ou6A-5g5zA:18.25"],["3OU6_B_SAMB300_0","SAM-DEPENDENT METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"LEU A 449;GLY A 348;GLY A 170;SER A 175;ALA A 429","None","1.05A","3ou6B-5g5zA:undetectable","3ou6B-5g5zA:18.25"],["3OU7_B_SAMB300_0","SAM-DEPENDENT METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"LEU A 449;GLY A 348;GLY A 170;SER A 175;ALA A 429","None","1.03A","3ou7B-5g5zA:undetectable","3ou7B-5g5zA:18.25"],["3P50_A_PFLA319_1","GLR4197 PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PRO A 103;ILE A  97;THR A 357;ILE A 125","None","0.97A","3p50A-5g5zA:undetectable","3p50A-5g5zA:19.32"],["3P50_B_PFLB319_1","GLR4197 PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PRO A 103;ILE A  97;THR A 357;ILE A 125","None","0.97A","3p50B-5g5zA:undetectable","3p50B-5g5zA:19.32"],["3P50_C_PFLC319_1","GLR4197 PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PRO A 103;ILE A  97;THR A 357;ILE A 125","None","0.97A","3p50C-5g5zA:undetectable","3p50C-5g5zA:19.32"],["3P50_D_PFLD320_1","GLR4197 PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PRO A 103;ILE A  97;THR A 357;ILE A 125","None","0.97A","3p50D-5g5zA:undetectable","3p50D-5g5zA:19.32"],["3P50_E_PFLE319_1","GLR4197 PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PRO A 103;ILE A  97;THR A 357;ILE A 125","None","0.96A","3p50E-5g5zA:undetectable","3p50E-5g5zA:19.32"],["3QL3_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ILE A 490;ASP A 249;ILE A 498;TYR A 510;THR A 265","None","1.23A","3ql3A-5g5zA:undetectable","3ql3A-5g5zA:15.20"],["3V8V_B_SAMB801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLY A 321;ASP A 327;VAL A 328;ASN A 318;LEU A 451","None;None;None;DQR A 544 (-3.1A);None","1.14A","3v8vB-5g5zA:undetectable","3v8vB-5g5zA:22.83"],["3WIP_G_ACTG305_0","ACETYLCHOLINE-BINDING PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ASP A 181;ARG A 494;LYS A 239","None","1.23A","3wipG-5g5zA:undetectable","3wipG-5g5zA:17.08"],["4AZT_A_SAMA1472_1","METHYLTRANSFERASE WBDD","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"GLN A  70;ASP A 389;GLN A 392","None","0.90A","4aztA-5g5zA:undetectable","4aztA-5g5zA:21.94"],["4B17_A_SAMA1358_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLY A 110;GLY A 426;GLY A 425;ASP A 109;ASP A 115","None","0.96A","4b17A-5g5zA:undetectable","4b17A-5g5zA:19.67"],["4DJE_B_C2FB302_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLU A 515;MET A 486;ASP A 267;ASN A 268;SER A 520","None;None; CA A 546 (-3.0A); CA A 546 (-2.9A);None","1.45A","4djeB-5g5zA:undetectable","4djeB-5g5zA:20.04"],["4DJF_B_C2FB300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLU A 515;MET A 486;ASP A 267;ASN A 268;SER A 520","None;None; CA A 546 (-3.0A); CA A 546 (-2.9A);None","1.47A","4djfB-5g5zA:undetectable","4djfB-5g5zA:20.04"],["4G5J_A_0WMA1102_1","EPIDERMAL GROWTH FACTOR RECEPTOR","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"PHE A 349;ILE A 142;TYR A 374;PRO A 164","None","1.16A","4g5jA-5g5zA:undetectable","4g5jA-5g5zA:23.15"],["4G8Z_X_TOPX301_1","DIHYDROFOLATE REDUCTASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ILE A 126;ALA A 120;LEU A 116;PRO A 164;ILE A 356","None","1.18A","4g8zX-5g5zA:undetectable","4g8zX-5g5zA:16.84"],["4KOT_A_CE3A205_1","UNCHARACTERIZED PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"GLY A 234;ASN A 180;ILE A 230;PHE A 238;TYR A 299","None","1.30A","4kotA-5g5zA:undetectable","4kotA-5g5zA:16.03"],["4KOT_A_CE3A205_1","UNCHARACTERIZED PROTEIN","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"PHE A 242;GLY A 234;ASN A 180;ILE A 230;PHE A 238","None","1.36A","4kotA-5g5zA:undetectable","4kotA-5g5zA:16.03"],["4KYK_B_IMNB300_1","LACTOYLGLUTATHIONE LYASE;LACTOYLGLUTATHIONE LYASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"PHE A 277;LEU A 241;GLY A 285;LYS A 284;LEU A 208","None","1.19A","4kykA-5g5zA:undetectable;4kykB-5g5zA:undetectable","4kykA-5g5zA:16.43;4kykB-5g5zA:16.43"],["4PBH_A_BEZA401_0","TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ILE A 278;ALA A 244;LEU A 281;LEU A 204;PHE A 245","None","1.44A","4pbhA-5g5zA:undetectable","4pbhA-5g5zA:22.40"],["4PTJ_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"ASP A 531;LYS A 526;LEU A 254","None","1.06A","4ptjA-5g5zA:undetectable","4ptjA-5g5zA:15.20"],["5B2O_A_ACTA1728_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"GLN A 392;THR A 386;ASP A 389;ASN A 394","None","1.47A","5b2oA-5g5zA:0.0","5b2oA-5g5zA:14.17"],["5B2P_A_ACTA1728_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"GLN A 392;THR A 386;ASP A 389;ASN A 394","None","1.47A","5b2pA-5g5zA:0.5","5b2pA-5g5zA:14.17"],["5B2Q_A_ACTA1729_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"GLN A 392;THR A 386;ASP A 389;ASN A 394","None","1.48A","5b2qA-5g5zA:0.0","5b2qA-5g5zA:14.17"],["5DV4_A_NMYA601_2","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"GLU A  75;TRP A 369;ASN A 138","None","1.15A","5dv4A-5g5zA:undetectable","5dv4A-5g5zA:21.92"],["5IGV_A_ZITA404_2","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"ASN A 180;ILE A 247;TYR A 271;PHE A 277","None","1.07A","5igvA-5g5zA:undetectable","5igvA-5g5zA:21.78"],["5JLC_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",5,"ALA A  90;ILE A 142;TYR A 374;PHE A 349;THR A 154","None","1.30A","5jlcA-5g5zA:undetectable","5jlcA-5g5zA:23.75"],["5M0I_B_ACTB303_0","SWI5-DEPENDENT HO EXPRESSION PROTEIN 2","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"VAL A 256;ASN A 250;ASP A 252;LEU A 254","None","1.31A","5m0iB-5g5zA:undetectable","5m0iB-5g5zA:19.51"],["6I0Y_A_TRPA3001_0","23S RIBOSOMAL RNA;TRYPTOPHANASE OPERON LEADER PEPTIDE","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",3,"TRP A 184;ILE A 185;ASP A 327","None","0.84A","6i0y7-5g5zA:undetectable","6i0y7-5g5zA:5.13"],["6MN4_B_AM2B301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"TRP A 314;HIS A 177;GLU A 167;GLU A 423","DQR A 544 (-4.1A);DQR A 544 (-4.7A);DQR A 544 (-2.8A);DQR A 544 (-2.8A)","1.14A","6mn4B-5g5zA:undetectable","6mn4B-5g5zA:19.19"],["6MN4_F_AM2F301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5g5z","ABC TRANSPORTER, SUBSTRATE-BINDING PROTEIN","Streptococcus pneumoniae",4,"TRP A 314;HIS A 177;GLU A 167;GLU A 423","DQR A 544 (-4.1A);DQR A 544 (-4.7A);DQR A 544 (-2.8A);DQR A 544 (-2.8A)","1.29A","6mn4F-5g5zA:undetectable","6mn4F-5g5zA:19.19"]]