SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gai'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 3 TRP Y 392
ALA Y 437
VAL Y 391
 None
 0.96A 1c4dA-5gaiY:
undetectable
1c4dB-5gaiY:
undetectable		 1c4dA-5gaiY:
1.89
1c4dB-5gaiY:
1.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.05A 1c8lA-5gaiY:
undetectable		 1c8lA-5gaiY:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		4 / 7 GLY K  79
PRO K  76
ASP K  47
SER K  70
 None
 0.95A 1gxsA-5gaiK:
undetectable
1gxsB-5gaiK:
undetectable		 1gxsA-5gaiK:
18.89
1gxsB-5gaiK:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 SER Y 385
PHE Y 382
PHE Y 337
GLY Y 349
 None
 1.09A 1icuC-5gaiY:
undetectable
1icuD-5gaiY:
undetectable		 1icuC-5gaiY:
15.12
1icuD-5gaiY:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 PHE Y 337
GLY Y 349
SER Y 385
PHE Y 382
 None
 1.17A 1icuC-5gaiY:
undetectable
1icuD-5gaiY:
undetectable		 1icuC-5gaiY:
15.12
1icuD-5gaiY:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 PHE Y 337
GLY Y 349
SER Y 385
PHE Y 382
 None
 1.21A 1icvA-5gaiY:
undetectable
1icvB-5gaiY:
undetectable		 1icvA-5gaiY:
15.12
1icvB-5gaiY:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.09A 1l5qA-5gaiY:
undetectable		 1l5qA-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.08A 1l5qB-5gaiY:
undetectable		 1l5qB-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.10A 1l7xB-5gaiY:
undetectable		 1l7xB-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 GLU A 548
LEU A 554
LEU A 551
LEU A 553
 None
 0.95A 1np1A-5gaiA:
undetectable		 1np1A-5gaiA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 MET A 102
ARG A 145
ILE A 293
HIS A 177
 None
 1.27A 1osvB-5gaiA:
undetectable		 1osvB-5gaiA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 4 LEU Y 145
ILE Y 181
ARG Y 266
TYR Y 151
 None
 1.33A 1rk3A-5gaiY:
undetectable		 1rk3A-5gaiY:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 7 SER Y 462
ILE Y 476
ILE Y 478
THR Y 516
 None
 0.99A 1sbrB-5gaiY:
undetectable		 1sbrB-5gaiY:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 4 SER Y 261
ASP Y 150
ARG Y 149
ASP Y 148
 None
 1.43A 2bm9C-5gaiY:
undetectable		 2bm9C-5gaiY:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 12 VAL Y 237
GLY Y 302
TYR Y 233
TYR Y 329
SER Y 198
 None
 1.25A 2cl5A-5gaiY:
undetectable		 2cl5A-5gaiY:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 9 ILE A 333
VAL A 397
PRO A 398
ILE A 340
VAL A 341
 None
 1.07A 2nnhB-5gaiA:
undetectable		 2nnhB-5gaiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 ILE Y  92
PHE Y  23
GLY Y  71
ILE Y  73
 None
 0.93A 2qwxA-5gaiY:
undetectable
2qwxB-5gaiY:
undetectable		 2qwxA-5gaiY:
14.84
2qwxB-5gaiY:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 SER A 279
HIS A 297
ASP A 166
 None
 0.72A 2wa2B-5gaiA:
undetectable		 2wa2B-5gaiA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 LEU Y 145
ILE Y 181
ARG Y 266
TYR Y 151
 None
 1.35A 2zlcA-5gaiY:
undetectable		 2zlcA-5gaiY:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 9 VAL Y 363
SER Y 361
LEU Y 397
ILE Y 429
GLY Y 324
 None
 1.23A 3cv9A-5gaiY:
undetectable		 3cv9A-5gaiY:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.06A 3dd1A-5gaiY:
undetectable		 3dd1A-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.12A 3dd1B-5gaiY:
undetectable		 3dd1B-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.08A 3ddwA-5gaiY:
undetectable		 3ddwA-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.08A 3ddwB-5gaiY:
undetectable		 3ddwB-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 12 SER Y 198
GLY Y 301
LEU Y 279
LYS Y 229
VAL Y 204
 None
 1.22A 3fzgA-5gaiY:
undetectable		 3fzgA-5gaiY:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 GLU A 503
ASP A 237
ASP A 509
 None
 0.71A 3jb2A-5gaiA:
undetectable		 3jb2A-5gaiA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 LEU Y 215
THR Y 216
GLY Y 439
ALA Y 437
 None
 0.84A 3jusA-5gaiY:
undetectable		 3jusA-5gaiY:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 LEU Y 215
THR Y 216
GLY Y 439
ALA Y 437
 None
 0.84A 3jusA-5gaiY:
undetectable		 3jusA-5gaiY:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 VAL Y  26
GLY Y  71
ILE Y  73
GLY Y  29
 None
 0.79A 3n9jB-5gaiY:
undetectable		 3n9jB-5gaiY:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 3 GLN Y 593
THR Y 592
LEU Y 563
 None
 0.66A 3ondA-5gaiY:
undetectable		 3ondA-5gaiY:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 3 GLN Y 593
THR Y 592
LEU Y 563
 None
 0.67A 3ondB-5gaiY:
undetectable		 3ondB-5gaiY:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 3 TYR Y 591
ASP Y 603
ASP Y 573
 None
 0.85A 3ou6B-5gaiY:
undetectable		 3ou6B-5gaiY:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 9 ILE Y  82
ILE Y  73
VAL Y  49
ILE Y  31
ILE Y  33
 None
 1.08A 3p4wB-5gaiY:
undetectable		 3p4wB-5gaiY:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 10 ILE Y  82
ILE Y  73
VAL Y  49
ILE Y  31
ILE Y  33
 None
 1.08A 3p4wD-5gaiY:
undetectable		 3p4wD-5gaiY:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 10 ILE Y  82
ILE Y  73
VAL Y  49
ILE Y  31
ILE Y  33
 None
 1.09A 3p4wE-5gaiY:
undetectable		 3p4wE-5gaiY:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 ILE Y 306
THR Y 327
SER Y 355
PHE Y 353
 None
 1.16A 3snfA-5gaiY:
undetectable		 3snfA-5gaiY:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 7 ASN Y 475
ILE Y 454
PHE Y 442
MET Y 444
 None
 1.17A 3tvxB-5gaiY:
undetectable		 3tvxB-5gaiY:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 456
ASN A 140
ILE A 271
ARG A 513
ASP A 509
 None
 1.36A 3w37A-5gaiA:
undetectable		 3w37A-5gaiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 6 THR Y 262
ASN Y 179
ASP Y 177
ILE Y 259
 None
 1.28A 3w9tB-5gaiY:
undetectable		 3w9tB-5gaiY:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 10 ALA Y 399
GLY Y 368
LEU Y 420
ASP Y 412
ILE Y 415
 None
 0.99A 3wdmB-5gaiY:
undetectable		 3wdmB-5gaiY:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 9 ALA Y 399
GLY Y 368
LEU Y 420
ASP Y 412
ILE Y 415
 None
 1.10A 3wdmC-5gaiY:
undetectable		 3wdmC-5gaiY:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 456
ASN A 140
ILE A 271
ARG A 513
ASP A 509
 None
 1.38A 3welA-5gaiA:
undetectable		 3welA-5gaiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 6 TYR A 447
ARG A 458
ASP A  77
LEU A  94
 None
 1.17A 4ax8A-5gaiA:
undetectable		 4ax8A-5gaiA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 GLN A 142
ALA A 454
ARG A 273
ILE A 251
GLU A 230
 None
 1.13A 4azsA-5gaiA:
undetectable		 4azsA-5gaiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 GLN A 142
ALA A 454
ARG A 273
ILE A 251
GLU A 230
 None
 1.18A 4azwA-5gaiA:
undetectable		 4azwA-5gaiA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		4 / 4 ALA K  97
VAL K  28
ASP K  31
LEU K  18
 None
 1.22A 4e7gA-5gaiK:
undetectable		 4e7gA-5gaiK:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 11 VAL A 320
ALA A 121
ASP A  32
LEU A  45
VAL A  38
 None
 1.46A 4eilA-5gaiA:
undetectable		 4eilA-5gaiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		4 / 6 GLU K  78
ARG K  20
ASP K  80
ASP K  81
 None
 1.28A 4kcnA-5gaiK:
undetectable		 4kcnA-5gaiK:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		4 / 6 GLU K  78
ARG K  20
ASP K  80
ASP K  81
 None
 1.28A 4kcnB-5gaiK:
undetectable		 4kcnB-5gaiK:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 11 VAL A 320
ALA A 121
ASP A  32
LEU A  45
VAL A  38
 None
 1.45A 4kyaA-5gaiA:
undetectable		 4kyaA-5gaiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 10 VAL A 320
ALA A 121
ASP A  32
LEU A  45
VAL A  38
 None
 1.46A 4kyaC-5gaiA:
undetectable		 4kyaC-5gaiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 THR A 100
THR A 138
ASP A 101
TYR A 447
 None
 1.05A 4oltA-5gaiA:
undetectable		 4oltA-5gaiA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 ARG Y 266
THR Y 158
THR Y 183
ASP Y 160
 None
 1.05A 4oltA-5gaiY:
undetectable		 4oltA-5gaiY:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 THR A 100
THR A 138
ASP A 101
TYR A 447
 None
 1.05A 4oltB-5gaiA:
undetectable		 4oltB-5gaiA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 ARG Y 266
THR Y 158
THR Y 183
ASP Y 160
 None
 1.00A 4oltB-5gaiY:
undetectable		 4oltB-5gaiY:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		3 / 3 PRO K 138
MET K 141
TYR K 137
 None
 1.13A 4qa0B-5gaiK:
undetectable		 4qa0B-5gaiK:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 ILE Y  92
PHE Y  23
GLY Y  71
ILE Y  73
 None
 0.96A 4qogA-5gaiY:
undetectable
4qogB-5gaiY:
undetectable		 4qogA-5gaiY:
14.84
4qogB-5gaiY:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 THR A 100
THR A 138
ASP A 101
TYR A 447
 None
 1.04A 4qwpA-5gaiA:
undetectable		 4qwpA-5gaiA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 ARG Y 266
THR Y 158
THR Y 183
ASP Y 160
 None
 0.97A 4qwpA-5gaiY:
undetectable		 4qwpA-5gaiY:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 THR A 100
THR A 138
ASP A 101
TYR A 447
 None
 1.05A 4qwpB-5gaiA:
undetectable		 4qwpB-5gaiA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 ARG Y 266
THR Y 158
THR Y 183
ASP Y 160
 None
 0.96A 4qwpB-5gaiY:
undetectable		 4qwpB-5gaiY:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 ASP A  18
ARG A  26
PRO A 204
 None
 1.06A 4wanC-5gaiA:
undetectable		 4wanC-5gaiA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 12 ASP Y 396
ASP Y 393
ALA Y 399
GLN Y 367
HIS Y 421
 None
 1.36A 4wh5A-5gaiY:
undetectable		 4wh5A-5gaiY:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 VAL A  68
LEU A  67
ARG A 116
ILE A 119
VAL A 415
 None
 1.09A 4y8wA-5gaiA:
undetectable		 4y8wA-5gaiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		5 / 12 VAL A  68
LEU A  67
ARG A 116
ILE A 119
VAL A 415
 None
 1.06A 4y8wB-5gaiA:
undetectable		 4y8wB-5gaiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 10 LEU Y 397
SER Y 385
GLY Y 349
VAL Y 350
THR Y 365
 None
 1.36A 4yb6D-5gaiY:
undetectable
4yb6E-5gaiY:
undetectable		 4yb6D-5gaiY:
19.66
4yb6E-5gaiY:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 5 GLY Y 178
GLY Y 156
GLU Y 157
 None
 0.52A 4z2eA-5gaiY:
undetectable
4z2eD-5gaiY:
undetectable		 4z2eA-5gaiY:
20.47
4z2eD-5gaiY:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 5 VAL Y 294
ILE Y 205
PRO Y 299
THR Y 260
 None
 1.19A 4ze1A-5gaiY:
undetectable		 4ze1A-5gaiY:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		4 / 5 ILE A 298
ILE A 293
TYR A 223
GLU A 221
 None
 0.98A 4zzcE-5gaiA:
undetectable		 4zzcE-5gaiA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 10 ILE Y 265
PHE Y 285
ILE Y 181
VAL Y 194
MET Y 293
 None
 1.26A 5jl7A-5gaiY:
undetectable		 5jl7A-5gaiY:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 TYR A  48
SER A  46
TRP A  41
 None
 1.03A 5n8jB-5gaiA:
undetectable		 5n8jB-5gaiA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		4 / 8 PRO Y 405
THR Y 374
THR Y 369
PRO Y 424
 None
 1.23A 5x2sI-5gaiY:
undetectable
5x2sJ-5gaiY:
undetectable
5x2sK-5gaiY:
undetectable		 5x2sI-5gaiY:
13.51
5x2sJ-5gaiY:
12.78
5x2sK-5gaiY:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 TYR A  98
ARG A  99
THR A 100
 None
 1.02A 5z84J-5gaiA:
undetectable		 5z84J-5gaiA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		3 / 3 PHE Y 243
ARG Y 357
ALA Y 460
 None
 0.87A 6ecfB-5gaiY:
undetectable		 6ecfB-5gaiY:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 5gai TAIL FIBER PROTEIN
(Salmonella
virus
P22) 		5 / 12 GLY Y 441
GLY Y 463
ILE Y 454
VAL Y 434
LEU Y 433
 None
 1.00A 6ectA-5gaiY:
undetectable		 6ectA-5gaiY:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5gai PEPTIDOGLYCAN
HYDROLASE GP4
(Salmonella
virus
P22) 		3 / 3 VAL K  46
ALA K  21
GLN K  43
 None
 0.60A 6gb9A-5gaiK:
undetectable		 6gb9A-5gaiK:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 5gai PORTAL PROTEIN
(Salmonella
virus
P22) 		3 / 3 ASP A 473
ASP A 460
ASN A 452
 None
 0.81A 6gngB-5gaiA:
undetectable		 6gngB-5gaiA:
20.61