SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ggg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 LEU A 622
LEU A 555
HIS A 573
LEU A 439
None
0.89A 1errA-5gggA:
undetectable
1errA-5gggA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 11 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.04A 1gtnM-5gggA:
undetectable
1gtnN-5gggA:
undetectable
1gtnM-5gggA:
8.92
1gtnN-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.98A 1gtnU-5gggA:
undetectable
1gtnV-5gggA:
2.0
1gtnU-5gggA:
8.92
1gtnV-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.03A 1gtnL-5gggA:
2.0
1gtnV-5gggA:
2.0
1gtnL-5gggA:
8.92
1gtnV-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 4 ASP A 436
LEU A 440
LEU A 530
LEU A 439
None
1.42A 1u18A-5gggA:
undetectable
1u18A-5gggA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 1utdO-5gggA:
undetectable
1utdP-5gggA:
undetectable
1utdO-5gggA:
8.92
1utdP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 11 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.02A 1utdP-5gggA:
undetectable
1utdQ-5gggA:
undetectable
1utdP-5gggA:
8.92
1utdQ-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 1utdT-5gggA:
undetectable
1utdU-5gggA:
undetectable
1utdT-5gggA:
8.92
1utdU-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 9 SER A 247
GLN A 138
PHE A 212
GLY A 222
ILE A 174
None
1.46A 2dr6A-5gggA:
undetectable
2dr6A-5gggA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 SER A 226
HIS A 132
ASP A 150
None
0.72A 2wa2B-5gggA:
undetectable
2wa2B-5gggA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 5 VAL A 278
TYR A 275
VAL A 347
ASP A 346
None
1.01A 2x45A-5gggA:
undetectable
2x45A-5gggA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 5 VAL A 278
TYR A 275
VAL A 347
ASP A 346
None
1.03A 2x45C-5gggA:
undetectable
2x45C-5gggA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 8 TYR A 441
SER A 535
HIS A 608
ARG A 613
None
1.21A 3b9lA-5gggA:
undetectable
3b9lA-5gggA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 THR A 285
SER A 277
PHE A 268
None
0.82A 3d4sA-5gggA:
undetectable
3d4sA-5gggA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 5 PRO A 493
SER A 423
LEU A 530
SER A 409
None
1.20A 3ijxH-5gggA:
undetectable
3ijxH-5gggA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 122
ASP A 179
None
0.73A 3jayA-5gggA:
undetectable
3jayA-5gggA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 122
ASP A 179
None
0.75A 3jb2A-5gggA:
undetectable
3jb2A-5gggA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 122
ASP A 179
None
0.73A 3jb3A-5gggA:
undetectable
3jb3A-5gggA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 GLY A 205
ASP A 208
ASP A 236
None
0.38A 3ou7C-5gggA:
undetectable
3ou7C-5gggA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 7 ILE A 134
PHE A 163
MET A 166
GLY A 274
None
1.24A 3sj0X-5gggA:
undetectable
3sj0X-5gggA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 5 LEU A 457
ARG A 485
ARG A 488
ARG A 480
None
1.32A 3ticA-5gggA:
undetectable
3ticA-5gggA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 LEU A 614
ILE A 642
LEU A 644
HIS A 557
LEU A 555
None
1.16A 4j24D-5gggA:
undetectable
4j24D-5gggA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 427
TRP A 475
SER A 423
None
1.00A 4lrhB-5gggA:
undetectable
4lrhB-5gggA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 427
TRP A 475
SER A 423
None
1.03A 4lrhF-5gggA:
undetectable
4lrhF-5gggA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 7 GLU A 394
GLU A 393
TYR A 372
LEU A 376
None
1.13A 4twdF-5gggA:
undetectable
4twdJ-5gggA:
undetectable
4twdF-5gggA:
17.62
4twdJ-5gggA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 179
ARG A 207
TYR A 152
None
0.90A 5a7mA-5gggA:
undetectable
5a7mA-5gggA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 179
ARG A 207
TYR A 152
None
0.92A 5a7mB-5gggA:
undetectable
5a7mB-5gggA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 LEU A 597
HIS A 520
ASN A 426
LEU A 439
PHE A 615
None
1.37A 5dv4A-5gggA:
2.3
5dv4A-5gggA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 4 LEU A 406
ILE A 422
PRO A 493
LEU A 530
None
1.20A 5eb3A-5gggA:
undetectable
5eb3A-5gggA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.01A 5eeuF-5gggA:
undetectable
5eeuG-5gggA:
undetectable
5eeuF-5gggA:
8.92
5eeuG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.00A 5eeuI-5gggA:
2.4
5eeuJ-5gggA:
2.4
5eeuI-5gggA:
8.92
5eeuJ-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eeuO-5gggA:
2.0
5eeuP-5gggA:
2.0
5eeuO-5gggA:
8.92
5eeuP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.98A 5eeuQ-5gggA:
2.0
5eeuR-5gggA:
2.0
5eeuQ-5gggA:
8.92
5eeuR-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.01A 5eevF-5gggA:
2.4
5eevG-5gggA:
undetectable
5eevF-5gggA:
8.92
5eevG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.00A 5eevI-5gggA:
undetectable
5eevJ-5gggA:
undetectable
5eevI-5gggA:
8.92
5eevJ-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eevO-5gggA:
2.0
5eevP-5gggA:
2.0
5eevO-5gggA:
8.92
5eevP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.98A 5eevQ-5gggA:
2.0
5eevR-5gggA:
2.0
5eevQ-5gggA:
8.92
5eevR-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5eewF-5gggA:
2.3
5eewG-5gggA:
undetectable
5eewF-5gggA:
8.92
5eewG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.01A 5eewI-5gggA:
undetectable
5eewJ-5gggA:
undetectable
5eewI-5gggA:
8.92
5eewJ-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eewO-5gggA:
2.0
5eewP-5gggA:
undetectable
5eewO-5gggA:
8.92
5eewP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eewQ-5gggA:
2.0
5eewR-5gggA:
1.7
5eewQ-5gggA:
8.92
5eewR-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5eexF-5gggA:
2.3
5eexG-5gggA:
undetectable
5eexF-5gggA:
8.92
5eexG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eexO-5gggA:
2.0
5eexP-5gggA:
undetectable
5eexO-5gggA:
8.92
5eexP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5eeyF-5gggA:
2.0
5eeyG-5gggA:
undetectable
5eeyF-5gggA:
8.92
5eeyG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eeyO-5gggA:
2.0
5eeyP-5gggA:
undetectable
5eeyO-5gggA:
8.92
5eeyP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5eezF-5gggA:
undetectable
5eezG-5gggA:
undetectable
5eezF-5gggA:
8.92
5eezG-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5eezO-5gggA:
2.0
5eezP-5gggA:
undetectable
5eezO-5gggA:
8.92
5eezP-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5ef0F-5gggA:
undetectable
5ef0G-5gggA:
undetectable
5ef0F-5gggA:
8.92
5ef0G-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5ef0O-5gggA:
2.0
5ef0P-5gggA:
2.0
5ef0O-5gggA:
8.92
5ef0P-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5ef1F-5gggA:
2.4
5ef1G-5gggA:
undetectable
5ef1F-5gggA:
8.92
5ef1G-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 5ef1O-5gggA:
2.0
5ef1P-5gggA:
2.0
5ef1O-5gggA:
8.92
5ef1P-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5ef2F-5gggA:
2.4
5ef2G-5gggA:
undetectable
5ef2F-5gggA:
8.92
5ef2G-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5ef2O-5gggA:
2.0
5ef2P-5gggA:
2.0
5ef2O-5gggA:
8.92
5ef2P-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.02A 5ef3F-5gggA:
2.4
5ef3G-5gggA:
undetectable
5ef3F-5gggA:
8.92
5ef3G-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5ef3O-5gggA:
2.0
5ef3P-5gggA:
undetectable
5ef3O-5gggA:
8.92
5ef3P-5gggA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 7 ARG A 616
VAL A 623
ALA A 577
LEU A 597
None
0.59A 5jq7A-5gggA:
undetectable
5jq7A-5gggA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 VAL A 335
VAL A 328
MET A 318
ALA A 308
VAL A 390
None
1.17A 5tudA-5gggA:
undetectable
5tudA-5gggA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.26A 5x7pA-5gggA:
undetectable
5x7pA-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.28A 5x7pB-5gggA:
2.6
5x7pB-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.27A 5x7qA-5gggA:
2.8
5x7qA-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.23A 5x7qB-5gggA:
2.5
5x7qB-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.28A 5x7rA-5gggA:
undetectable
5x7rA-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 6 TRP A 206
SER A 182
ARG A 129
TYR A 152
None
1.27A 5x7rB-5gggA:
2.8
5x7rB-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 5 PHE A 268
VAL A 335
PRO A 312
VAL A 272
None
1.35A 6ekzA-5gggA:
undetectable
6ekzA-5gggA:
8.83