SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ggk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 11 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.05A 1gtnM-5ggkA:
1.3
1gtnN-5ggkA:
1.3
1gtnM-5ggkA:
23.23
1gtnN-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
0.99A 1gtnU-5ggkA:
1.4
1gtnV-5ggkA:
1.4
1gtnU-5ggkA:
23.23
1gtnV-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.04A 1gtnL-5ggkA:
1.4
1gtnV-5ggkA:
1.4
1gtnL-5ggkA:
23.23
1gtnV-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 PHE A 212
LEU A 173
VAL A 167
PHE A 163
VAL A 133
None
1.46A 1q23K-5ggkA:
undetectable
1q23K-5ggkA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.02A 1utdO-5ggkA:
undetectable
1utdP-5ggkA:
undetectable
1utdO-5ggkA:
23.23
1utdP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 11 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.04A 1utdP-5ggkA:
undetectable
1utdQ-5ggkA:
1.3
1utdP-5ggkA:
23.23
1utdQ-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.03A 1utdT-5ggkA:
1.4
1utdU-5ggkA:
1.4
1utdT-5ggkA:
23.23
1utdU-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 157
ASP A 187
EDO  A 305 ( 3.6A)
None
None
0.63A 2ejtA-5ggkA:
undetectable
2ejtA-5ggkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 PHE A 212
LEU A 136
VAL A 114
LEU A 196
LEU A 164
None
1.14A 2prgB-5ggkA:
undetectable
2prgB-5ggkA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 122
ASP A 179
EDO  A 305 ( 3.6A)
None
MBE  A 301 ( 3.0A)
0.76A 3jayA-5ggkA:
undetectable
3jayA-5ggkA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ARG A 129
ASP A 122
ASP A 179
EDO  A 305 ( 3.6A)
None
MBE  A 301 ( 3.0A)
0.58A 3jb3A-5ggkA:
undetectable
3jb3A-5ggkA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 GLY A 205
ASP A 208
ASP A 236
None
0.46A 3ou7C-5ggkA:
undetectable
3ou7C-5ggkA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 4 LYS A 224
ALA A 211
SER A 106
THR A 176
None
1.49A 4i89B-5ggkA:
undetectable
4i89B-5ggkA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 179
ARG A 207
TYR A 152
MBE  A 301 ( 3.0A)
MBE  A 301 (-3.9A)
MBE  A 301 (-4.2A)
0.95A 5a7mA-5ggkA:
undetectable
5a7mA-5ggkA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
3 / 3 ASP A 179
ARG A 207
TYR A 152
MBE  A 301 ( 3.0A)
MBE  A 301 (-3.9A)
MBE  A 301 (-4.2A)
0.97A 5a7mB-5ggkA:
undetectable
5a7mB-5ggkA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.05A 5eeuF-5ggkA:
1.4
5eeuG-5ggkA:
undetectable
5eeuF-5ggkA:
23.23
5eeuG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.03A 5eeuI-5ggkA:
1.4
5eeuJ-5ggkA:
1.4
5eeuI-5ggkA:
23.23
5eeuJ-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5eeuO-5ggkA:
1.4
5eeuP-5ggkA:
1.4
5eeuO-5ggkA:
23.23
5eeuP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5eeuQ-5ggkA:
1.3
5eeuR-5ggkA:
1.3
5eeuQ-5ggkA:
23.23
5eeuR-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5eevF-5ggkA:
1.4
5eevG-5ggkA:
undetectable
5eevF-5ggkA:
23.23
5eevG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.04A 5eevI-5ggkA:
1.4
5eevJ-5ggkA:
1.4
5eevI-5ggkA:
23.23
5eevJ-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5eevO-5ggkA:
1.4
5eevP-5ggkA:
1.4
5eevO-5ggkA:
23.23
5eevP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5eevQ-5ggkA:
1.3
5eevR-5ggkA:
1.4
5eevQ-5ggkA:
23.23
5eevR-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5eewF-5ggkA:
1.4
5eewG-5ggkA:
undetectable
5eewF-5ggkA:
23.23
5eewG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 12 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.04A 5eewI-5ggkA:
1.4
5eewJ-5ggkA:
1.4
5eewI-5ggkA:
23.23
5eewJ-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5eewO-5ggkA:
1.3
5eewP-5ggkA:
1.4
5eewO-5ggkA:
23.23
5eewP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5eewQ-5ggkA:
1.3
5eewR-5ggkA:
1.3
5eewQ-5ggkA:
23.23
5eewR-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5eexF-5ggkA:
1.4
5eexG-5ggkA:
undetectable
5eexF-5ggkA:
23.23
5eexG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5eexO-5ggkA:
1.3
5eexP-5ggkA:
1.4
5eexO-5ggkA:
23.23
5eexP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5eeyF-5ggkA:
1.4
5eeyG-5ggkA:
undetectable
5eeyF-5ggkA:
23.23
5eeyG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.00A 5eeyO-5ggkA:
1.4
5eeyP-5ggkA:
1.3
5eeyO-5ggkA:
23.23
5eeyP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5eezF-5ggkA:
1.4
5eezG-5ggkA:
undetectable
5eezF-5ggkA:
23.23
5eezG-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5eezO-5ggkA:
1.3
5eezP-5ggkA:
1.3
5eezO-5ggkA:
23.23
5eezP-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5ef0F-5ggkA:
1.4
5ef0G-5ggkA:
undetectable
5ef0F-5ggkA:
23.23
5ef0G-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5ef0O-5ggkA:
1.4
5ef0P-5ggkA:
1.4
5ef0O-5ggkA:
23.23
5ef0P-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5ef1F-5ggkA:
undetectable
5ef1G-5ggkA:
undetectable
5ef1F-5ggkA:
23.23
5ef1G-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5ef1O-5ggkA:
1.4
5ef1P-5ggkA:
1.3
5ef1O-5ggkA:
23.23
5ef1P-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5ef2F-5ggkA:
1.4
5ef2G-5ggkA:
undetectable
5ef2F-5ggkA:
23.23
5ef2G-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5ef2O-5ggkA:
1.4
5ef2P-5ggkA:
1.4
5ef2O-5ggkA:
23.23
5ef2P-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 ALA A 189
GLY A 181
HIS A 184
THR A 151
ILE A 131
None
1.06A 5ef3F-5ggkA:
1.4
5ef3G-5ggkA:
undetectable
5ef3F-5ggkA:
23.23
5ef3G-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
5 / 10 GLY A 181
HIS A 184
THR A 151
ILE A 131
ALA A 189
None
1.01A 5ef3O-5ggkA:
1.3
5ef3P-5ggkA:
1.3
5ef3O-5ggkA:
23.23
5ef3P-5ggkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo
sapiens)
4 / 7 THR A 176
PHE A 212
LEU A 173
SER A 195
None
1.27A 5uxcA-5ggkA:
undetectable
5uxcA-5ggkA:
20.39