SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ghe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.93A 1jnoA-5gheA:
undetectable		 1jnoA-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.92A 1jnoB-5gheA:
undetectable		 1jnoB-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.93A 1jo4A-5gheA:
undetectable		 1jo4A-5gheA:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.93A 1jo4B-5gheA:
undetectable		 1jo4B-5gheA:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.85A 1magA-5gheA:
undetectable		 1magA-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.85A 1magB-5gheA:
undetectable		 1magB-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.93A 1ng8A-5gheA:
undetectable		 1ng8A-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.93A 1ng8B-5gheA:
undetectable		 1ng8B-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.91A 1nrmA-5gheA:
undetectable		 1nrmA-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.90A 1nrmB-5gheA:
undetectable		 1nrmB-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.90A 1nruA-5gheA:
undetectable		 1nruA-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 ALA A 113
VAL A 373
TRP A 370
 None
 0.90A 1nruB-5gheA:
undetectable		 1nruB-5gheA:
2.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 5 ILE A 112
ILE A 339
ILE A 331
MET A  31
 None
 0.92A 1zgyA-5gheA:
undetectable		 1zgyA-5gheA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 8 PHE A  80
SER A  78
ALA A 214
LEU A 211
 None
 1.07A 2o01A-5gheA:
undetectable		 2o01A-5gheA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 7 TYR A 130
VAL A 119
TYR A 115
ILE A 339
 None
 1.13A 2x45B-5gheA:
undetectable		 2x45B-5gheA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 7 TYR A 130
VAL A 119
TYR A 115
ILE A 339
 None
 1.10A 2x45C-5gheA:
undetectable		 2x45C-5gheA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 ARG A  11
VAL A 373
ILE A 112
ILE A  38
PRO A  28
 None
 1.16A 2yzqA-5gheA:
undetectable		 2yzqA-5gheA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 ILE A  18
ARG A  11
VAL A 373
ILE A  38
PRO A  28
 None
 1.22A 2yzqA-5gheA:
undetectable		 2yzqA-5gheA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 PHE A 186
GLY A 189
ILE A 200
ASN A 199
ASP A  90
 None
 1.03A 2zzmA-5gheA:
undetectable		 2zzmA-5gheA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 PHE A 186
GLY A 189
ILE A 200
ASN A 199
ASP A  90
 None
 1.12A 2zznA-5gheA:
undetectable		 2zznA-5gheA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 10 PHE A 186
GLY A 189
ILE A 200
ASN A 199
ASP A  90
 None
 0.93A 3ay0B-5gheA:
undetectable		 3ay0B-5gheA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 7 TYR A 130
VAL A 119
TYR A 115
ILE A 339
 None
 1.21A 3bu1A-5gheA:
undetectable		 3bu1A-5gheA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 8 TYR A  50
THR A  53
GLY A 257
ILE A 240
 None
 0.75A 3jusA-5gheA:
1.5		 3jusA-5gheA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 8 TYR A  50
THR A  53
GLY A 257
ILE A 240
 None
 0.75A 3jusA-5gheA:
1.5		 3jusA-5gheA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 5 GLY A  54
LYS A  91
GLU A  95
GLY A  56
 None
 1.08A 3onnA-5gheA:
undetectable		 3onnA-5gheA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 LEU A 183
LEU A 101
ILE A  47
ILE A 105
TYR A 102
 None
 1.15A 4a7aB-5gheA:
undetectable		 4a7aB-5gheA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 5 ALA A 272
ILE A 240
LEU A 236
ASN A 270
 None
 1.01A 4g19A-5gheA:
undetectable		 4g19A-5gheA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 ILE A  76
GLN A  63
LEU A  64
LEU A  83
ILE A 307
 None
 1.15A 4g1bD-5gheA:
undetectable		 4g1bD-5gheA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 ARG A 343
GLY A 163
GLU A 173
ALA A 333
GLY A 336
 None
 1.24A 4r29B-5gheA:
undetectable		 4r29B-5gheA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 12 SER A  71
ILE A  76
PRO A  77
ASP A  79
ILE A 300
 None
 1.32A 4uroD-5gheA:
undetectable		 4uroD-5gheA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 11 LEU A 328
VAL A 324
LEU A 101
GLY A 318
SER A 108
 None
 1.17A 4zbqA-5gheA:
undetectable		 4zbqA-5gheA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 8 MET A 303
ARG A 203
HIS A  67
LEU A  64
 None
 0.98A 5dxeA-5gheA:
3.5		 5dxeA-5gheA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		3 / 3 MET A 303
HIS A  67
GLY A 261
 None
 0.75A 5gwzB-5gheA:
undetectable		 5gwzB-5gheA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		5 / 11 PHE A 186
GLY A 189
ILE A 200
ASN A 199
ASP A  90
 None
 0.95A 5hjiA-5gheA:
undetectable		 5hjiA-5gheA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 9 TYR A 315
ILE A 311
ILE A 307
LEU A 304
 None
 0.81A 5vkqB-5gheA:
2.4
5vkqC-5gheA:
2.4		 5vkqB-5gheA:
13.23
5vkqC-5gheA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA
(Bacillus
thuringiensis) 		4 / 8 MET A 303
ARG A 203
HIS A  67
LEU A  64
 None
 0.98A 6cbzA-5gheA:
3.3		 6cbzA-5gheA:
13.21