SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ghf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 5 LEU A 423
LEU A 385
SER A 453
LEU A 454
 None
 1.01A 1a4lC-5ghfA:
undetectable		 1a4lC-5ghfA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 6 ASN A 167
HIS A 180
ALA A 159
GLY A 153
 None
None
None
PMP  A 501 ( 3.7A)
 1.14A 1c8lA-5ghfA:
undetectable		 1c8lA-5ghfA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 ALA A 112
PHE A 114
LEU A 339
PHE A 264
MET A 285
 None
 1.00A 1dtlA-5ghfA:
undetectable		 1dtlA-5ghfA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 8 PHE A 271
GLY A 265
ARG A 266
LEU A 429
 None
 0.72A 1gsfC-5ghfA:
undetectable		 1gsfC-5ghfA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 8 PRO A 226
THR A 267
GLY A 263
CYH A 262
 None
 0.88A 1h4oB-5ghfA:
undetectable		 1h4oB-5ghfA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 8 ILE A 145
SER A 146
LEU A 210
GLU A 214
 None
 0.97A 2cdqA-5ghfA:
undetectable		 2cdqA-5ghfA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 6 ARG A 202
PRO A 237
LYS A 238
THR A 239
 None
 1.26A 2m2oB-5ghfA:
undetectable		 2m2oB-5ghfA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 ARG A 375
PHE A 276
TYR A 240
ARG A 149
GLY A 182
 None
 1.47A 2vufA-5ghfA:
undetectable		 2vufA-5ghfA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 ASP A 353
GLN A 288
GLY A  61
SER A  55
GLY A 355
 None
 1.15A 2y6rC-5ghfA:
undetectable		 2y6rC-5ghfA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		3 / 3 GLY A 268
GLY A 355
GLY A 378
 None
 0.39A 3bogC-5ghfA:
undetectable		 3bogC-5ghfA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 6 ASN A 167
HIS A 180
ALA A 159
GLY A 153
 None
None
None
PMP  A 501 ( 3.7A)
 1.16A 3ddsA-5ghfA:
undetectable		 3ddsA-5ghfA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 1.01A 3embA-5ghfA:
undetectable		 3embA-5ghfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 LEU A 294
ILE A 296
SER A 286
LEU A 289
SER A 290
 None
None
PMP  A 501 ( 4.3A)
None
None
 1.28A 3gyqA-5ghfA:
undetectable
3gyqB-5ghfA:
undetectable		 3gyqA-5ghfA:
22.39
3gyqB-5ghfA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 10 SER A  59
LEU A 347
ILE A 430
PRO A 428
GLY A  63
 None
 1.28A 3ijxB-5ghfA:
undetectable
3ijxD-5ghfA:
undetectable		 3ijxB-5ghfA:
19.21
3ijxD-5ghfA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 10 ILE A 430
PRO A 428
GLY A  63
SER A  59
LEU A 347
 None
 1.26A 3ik6B-5ghfA:
undetectable
3ik6E-5ghfA:
undetectable		 3ik6B-5ghfA:
19.21
3ik6E-5ghfA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A  61
SER A  55
SER A 292
ILE A 342
LEU A 429
 None
 1.29A 3iv6D-5ghfA:
undetectable		 3iv6D-5ghfA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 LEU A 379
ALA A  53
ALA A 418
GLU A 384
GLY A 229
 None
 1.04A 3nxuA-5ghfA:
undetectable		 3nxuA-5ghfA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 10 LEU A 365
PRO A 369
ALA A 452
GLU A 444
LEU A 385
 None
 1.15A 4la0A-5ghfA:
undetectable		 4la0A-5ghfA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 7 GLU A 225
ARG A 375
GLY A 232
GLY A 229
 PMP  A 501 (-3.9A)
None
None
None
 0.82A 4rdxA-5ghfA:
undetectable		 4rdxA-5ghfA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 6 GLU A 373
PHE A 186
PHE A 199
HIS A 185
 None
 1.31A 4uciA-5ghfA:
undetectable		 4uciA-5ghfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 7 GLU A 373
PHE A 186
PHE A 199
HIS A 185
 None
 1.33A 4uciB-5ghfA:
undetectable		 4uciB-5ghfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 6 ILE A 430
ARG A 345
ILE A 341
GLU A  66
 None
 1.13A 4zzcB-5ghfA:
undetectable
4zzcC-5ghfA:
undetectable		 4zzcB-5ghfA:
22.51
4zzcC-5ghfA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 8 GLU A 189
GLY A 231
TYR A 240
PHE A 199
 None
 1.00A 5flcB-5ghfA:
undetectable		 5flcB-5ghfA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		4 / 8 GLU A 189
GLY A 231
TYR A 240
PHE A 199
 None
 0.99A 5flcF-5ghfA:
undetectable		 5flcF-5ghfA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 TYR A 240
PRO A 226
VAL A 234
LEU A 164
LEU A 255
 None
 1.24A 5hv1A-5ghfA:
undetectable		 5hv1A-5ghfA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.91A 5wz1A-5ghfA:
undetectable		 5wz1A-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.92A 5wz1B-5ghfA:
undetectable		 5wz1B-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.90A 5wz1C-5ghfA:
undetectable		 5wz1C-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.91A 5wz1D-5ghfA:
undetectable		 5wz1D-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.91A 5wz1E-5ghfA:
undetectable		 5wz1E-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.92A 5wz1F-5ghfA:
undetectable		 5wz1F-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.89A 5wz1G-5ghfA:
undetectable		 5wz1G-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 12 GLY A 272
GLY A 263
GLU A 225
VAL A 125
ILE A 256
 None
None
PMP  A 501 (-3.9A)
None
None
 0.91A 5wz1H-5ghfA:
undetectable		 5wz1H-5ghfA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 7 VAL A 284
PRO A 280
ALA A 121
THR A 124
TYR A 113
 None
 1.47A 6cduH-5ghfA:
undetectable
6cduI-5ghfA:
undetectable		 6cduH-5ghfA:
23.28
6cduI-5ghfA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 5ghf AMINOTRANSFERASE
CLASS-III
(Ochrobactrum
anthropi) 		5 / 9 THR A 356
GLY A 355
GLY A 378
VAL A 227
CYH A 262
 None
 1.48A 6gnfA-5ghfA:
undetectable		 6gnfA-5ghfA:
21.91