SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 12 HIS A 180
ASP A 182
HIS A 237
SER A 163
PHE A 253
 ZN  A 401 ( 3.4A)
ZN  A 401 ( 2.2A)
ZN  A 401 ( 3.3A)
None
None
 1.13A 1uobA-5gjaA:
21.9		 1uobA-5gjaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		6 / 12 HIS A 180
ASP A 182
LEU A 198
HIS A 237
SER A 249
PHE A 253
 ZN  A 401 ( 3.4A)
ZN  A 401 ( 2.2A)
None
ZN  A 401 ( 3.3A)
6PC  A 402 ( 4.5A)
None
 0.62A 1uobA-5gjaA:
21.9		 1uobA-5gjaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 11 HIS A 180
ASP A 182
HIS A 237
VAL A 239
SER A 163
 ZN  A 401 ( 3.4A)
ZN  A 401 ( 2.2A)
ZN  A 401 ( 3.3A)
None
None
 1.13A 1uofA-5gjaA:
20.6		 1uofA-5gjaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		4 / 8 THR A 181
VAL A 235
SER A 234
GLU A 296
 None
 1.15A 2v41G-5gjaA:
undetectable
2v41H-5gjaA:
undetectable		 2v41G-5gjaA:
22.29
2v41H-5gjaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 10 ILE A 187
PHE A  36
TYR A 287
VAL A 239
LEU A 198
 6PC  A 402 ( 4.7A)
None
None
None
None
 1.47A 2w98A-5gjaA:
undetectable		 2w98A-5gjaA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		4 / 8 ARG A  96
VAL A 109
TYR A 113
VAL A  95
 None
 1.30A 2y05A-5gjaA:
undetectable
2y05B-5gjaA:
undetectable		 2y05A-5gjaA:
23.27
2y05B-5gjaA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		3 / 3 THR A 228
SER A 234
LYS A 295
 None
 1.16A 3aocC-5gjaA:
undetectable		 3aocC-5gjaA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 12 GLY A  35
ILE A 187
GLY A 185
LEU A 200
THR A 181
 None
6PC  A 402 ( 4.7A)
None
None
None
 1.08A 3eeyF-5gjaA:
undetectable		 3eeyF-5gjaA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 10 TRP A  89
LEU A  72
GLY A  76
VAL A  84
VAL A  87
 None
 1.21A 3lxiA-5gjaA:
undetectable		 3lxiA-5gjaA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 11 ASP A  88
HIS A 237
VAL A 239
LEU A 198
PRO A 166
 None
ZN  A 401 ( 3.3A)
None
None
None
 1.03A 3sm2B-5gjaA:
undetectable		 3sm2B-5gjaA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		4 / 7 PRO A   8
LEU A 131
GLY A  35
ALA A  30
 None
 0.94A 3tehB-5gjaA:
undetectable		 3tehB-5gjaA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		4 / 6 CYH A  63
THR A  62
ASP A 108
ILE A 106
 None
 1.24A 3w9tB-5gjaA:
undetectable		 3w9tB-5gjaA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 9 TRP A  89
LEU A  72
GLY A  76
VAL A  84
VAL A  87
 None
 1.25A 4c9kB-5gjaA:
undetectable		 4c9kB-5gjaA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 9 TRP A  89
LEU A  72
GLY A  76
VAL A  84
VAL A  87
 None
 1.23A 4c9pA-5gjaA:
undetectable		 4c9pA-5gjaA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		3 / 3 LYS A 175
ARG A 238
TRP A 206
 None
 1.33A 4i90A-5gjaA:
undetectable		 4i90A-5gjaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		3 / 3 HIS A  42
HIS A  46
HIS A 214
 None
 1.02A 5oexA-5gjaA:
undetectable		 5oexA-5gjaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  12
ILE A  27
CYH A  31
LEU A 224
ILE A 218
 None
 1.23A 5y2tB-5gjaA:
undetectable		 5y2tB-5gjaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2
(Arabidopsis
thaliana) 		4 / 8 LYS A 175
GLY A 176
LEU A 198
GLY A 197
 None
 0.55A 6mdqA-5gjaA:
undetectable		 6mdqA-5gjaA:
14.33