SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		6 / 11 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
ILE A  56
 None
 1.40A 1c6yA-5gjjA:
undetectable		 1c6yA-5gjjA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		5 / 9 ALA A 106
VAL A  54
ILE A  80
ILE A  43
THR A  21
 None
 1.02A 3el4B-5gjjA:
undetectable		 3el4B-5gjjA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		5 / 10 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
 None
 1.10A 3el5A-5gjjA:
undetectable		 3el5A-5gjjA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		5 / 9 LEU A  19
ALA A 106
VAL A  54
ILE A  43
THR A  21
 None
 1.13A 3spkA-5gjjA:
undetectable		 3spkA-5gjjA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		6 / 12 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
THR A  21
 None
 1.13A 3spkB-5gjjA:
undetectable		 3spkB-5gjjA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		6 / 11 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
THR A  21
 None
 1.32A 4njtC-5gjjA:
undetectable		 4njtC-5gjjA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		5 / 9 LEU A  19
ALA A 106
VAL A  54
ILE A  43
THR A  21
 None
 1.15A 4njtD-5gjjA:
undetectable		 4njtD-5gjjA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		6 / 12 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
THR A  21
 None
 1.14A 4njuA-5gjjA:
undetectable		 4njuA-5gjjA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		6 / 12 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
THR A  21
 None
 1.14A 4njuC-5gjjA:
undetectable		 4njuC-5gjjA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 5gjj HEAT SHOCK 70 KDA
PROTEIN 1A
(Homo
sapiens) 		5 / 12 LEU A  19
ALA A 106
VAL A  54
ILE A  80
ILE A  43
 None
 0.99A 6dilA-5gjjA:
undetectable		 6dilA-5gjjA:
15.08