SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_A_ACTA294_0 (GLYCINE N-METHYLTRANSFERASE)	5gjk	SWI/SNF COMPLEX SUBUNIT SMARCC1 (Homo sapiens)	4 / 5	TRP A 531 ILE A 465 LEU A 533 ALA A 454	None	0.74A	1xvaA-5gjkA: undetectable 1xvaB-5gjkA: undetectable	1xvaA-5gjkA: 14.73 1xvaB-5gjkA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_ACTB294_0 (GLYCINE N-METHYLTRANSFERASE)	5gjk	SWI/SNF COMPLEX SUBUNIT SMARCC1 (Homo sapiens)	4 / 6	ALA A 454 TRP A 531 ILE A 465 LEU A 533	None	0.74A	1xvaA-5gjkA: undetectable 1xvaB-5gjkA: undetectable	1xvaA-5gjkA: 14.73 1xvaB-5gjkA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_F_Z80F401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5gjk	SWI/SNF COMPLEX SUBUNIT SMARCC1 (Homo sapiens)	5 / 10	ILE A 448 ILE A 450 ASN A 491 ASP A 458 ILE A 494	None	1.24A	5lg3F-5gjkA: undetectable	5lg3F-5gjkA: 14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5gjk	SWI/SNF COMPLEX SUBUNIT SMARCC1 (Homo sapiens)	5 / 10	ILE A 448 ILE A 450 ASN A 491 ASP A 458 ILE A 494	None	1.24A	5lg3H-5gjkA: undetectable	5lg3H-5gjkA: 14.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XVA_A_ACTA294_0","GLYCINE N-METHYLTRANSFERASE","5gjk","SWI\/SNF COMPLEX SUBUNIT SMARCC1","Homo sapiens",4,"TRP A 531;ILE A 465;LEU A 533;ALA A 454","None","0.74A","1xvaA-5gjkA:undetectable;1xvaB-5gjkA:undetectable","1xvaA-5gjkA:14.73;1xvaB-5gjkA:14.73"],["1XVA_B_ACTB294_0","GLYCINE N-METHYLTRANSFERASE","5gjk","SWI\/SNF COMPLEX SUBUNIT SMARCC1","Homo sapiens",4,"ALA A 454;TRP A 531;ILE A 465;LEU A 533","None","0.74A","1xvaA-5gjkA:undetectable;1xvaB-5gjkA:undetectable","1xvaA-5gjkA:14.73;1xvaB-5gjkA:14.73"],["5LG3_F_Z80F401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5gjk","SWI\/SNF COMPLEX SUBUNIT SMARCC1","Homo sapiens",5,"ILE A 448;ILE A 450;ASN A 491;ASP A 458;ILE A 494","None","1.24A","5lg3F-5gjkA:undetectable","5lg3F-5gjkA:14.52"],["5LG3_H_Z80H401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5gjk","SWI\/SNF COMPLEX SUBUNIT SMARCC1","Homo sapiens",5,"ILE A 448;ILE A 450;ASN A 491;ASP A 458;ILE A 494","None","1.24A","5lg3H-5gjkA:undetectable","5lg3H-5gjkA:14.52"]]