SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 8 GLY A 319
PHE A 318
LEU A 285
GLY A 288
 None
 0.75A 1d0vA-5gjnA:
undetectable		 1d0vA-5gjnA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 8 SER A  73
VAL A  71
ALA A 104
GLU A  76
 None
 0.81A 1dmiA-5gjnA:
undetectable
1dmiB-5gjnA:
undetectable		 1dmiA-5gjnA:
20.13
1dmiB-5gjnA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 8 GLY A 319
PHE A 318
LEU A 285
GLY A 288
 None
 0.73A 1jhaA-5gjnA:
undetectable		 1jhaA-5gjnA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 7 TYR A 352
GLU A 255
HIS A 179
GLY A 217
 GOL  A 401 (-4.7A)
None
None
None
 1.26A 2ha4B-5gjnA:
undetectable		 2ha4B-5gjnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 8 SER A  26
PRO A 223
LEU A 232
THR A  55
 None
 0.97A 2v0zO-5gjnA:
undetectable		 2v0zO-5gjnA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 5 VAL A 110
TYR A  92
VAL A  71
ASP A  70
 None
 1.32A 2x45C-5gjnA:
undetectable		 2x45C-5gjnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		5 / 12 ARG A 112
LEU A 214
ILE A  91
ALA A 197
ASP A 213
 PGE  A 406 (-3.9A)
None
None
None
PGE  A 406 (-3.8A)
 1.04A 3axtA-5gjnA:
2.1		 3axtA-5gjnA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 6 GLY A 350
THR A  55
GLU A 348
GLU A  32
 None
 0.90A 3fpjA-5gjnA:
undetectable		 3fpjA-5gjnA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		3 / 3 HIS A 306
ARG A   5
GLU A 348
 None
 0.94A 3qf1A-5gjnA:
undetectable		 3qf1A-5gjnA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		5 / 11 MET A  50
GLY A 257
VAL A  71
ASN A  53
LEU A  80
 None
GOL  A 401 ( 3.1A)
None
None
None
 1.12A 3v8vB-5gjnA:
undetectable		 3v8vB-5gjnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 8 GLY A  64
LEU A  27
VAL A  30
TYR A  34
 None
 0.61A 4fgzB-5gjnA:
undetectable		 4fgzB-5gjnA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		3 / 3 MET A  90
MET A 124
TYR A 108
 None
 1.44A 4p6xI-5gjnA:
undetectable		 4p6xI-5gjnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 5 THR A 353
GLU A 287
THR A 269
LEU A 305
 None
 1.28A 5hm8G-5gjnA:
2.8		 5hm8G-5gjnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		5 / 12 ASN A 361
GLU A 287
GLY A 288
TYR A 290
ILE A 296
 None
 1.24A 5lsaA-5gjnA:
undetectable		 5lsaA-5gjnA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		5 / 10 HIS A 210
ARG A 112
HIS A 172
LEU A 134
THR A 212
 None
PGE  A 406 (-3.9A)
None
None
None
 1.27A 5m8nB-5gjnA:
undetectable		 5m8nB-5gjnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		4 / 5 THR A 353
GLU A 287
THR A 269
LEU A 305
 None
 1.23A 5utuH-5gjnA:
undetectable		 5utuH-5gjnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5gjn LYSINE/ORNITHINE
DECARBOXYLASE
(Selenomonas
ruminantium) 		3 / 3 GLU A 192
LEU A 195
ARG A 199
 None
 0.68A 6d8fA-5gjnA:
3.6		 6d8fA-5gjnA:
19.87