SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		4 / 5 LEU x 155
LEU x 174
LEU x 109
MET x 206
 None
 1.11A 2oaxF-5gjqx:
undetectable		 2oaxF-5gjqx:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		5 / 10 MET x 354
LEU x 352
ILE x 325
VAL x 248
GLY x 247
 None
 1.26A 2qd4B-5gjqx:
undetectable		 2qd4B-5gjqx:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		3 / 3 TRP x 471
TRP x 438
THR x 424
 None
 0.99A 4bboB-5gjqx:
undetectable		 4bboB-5gjqx:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		5 / 8 GLY x 105
LEU x 106
ASN x 116
GLN x 120
PHE x 449
 None
 0.86A 5xu8A-5gjqx:
undetectable		 5xu8A-5gjqx:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		3 / 3 PHE x 159
ASP x 160
LYS x 133
 None
 0.81A 6awtD-5gjqx:
undetectable		 6awtD-5gjqx:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens) 		4 / 5 ASN x 108
GLY x 427
HIS x 434
ASP x 450
 None
 0.64A 6gh9A-5gjqx:
undetectable		 6gh9A-5gjqx:
11.34