SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	GLU F 760 THR F 739 VAL F 738 ALA F 665	None	1.11A	1fo4B-5gjwF: undetectable	1fo4B-5gjwF: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NR6_A_DIFA501_1 (CYTOCHROME P450 2C5)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 9	ALA F 712 GLY F 742 LEU F 683 LEU F 651 PHE F 686	None	1.08A	1nr6A-5gjwF: undetectable	1nr6A-5gjwF: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OXR_A_AINA141_1 (PHOSPHOLIPASE A2 ISOFORM 3)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 4	LEU F 59 GLY F 713 ASP F 711 TYR F 63	None	1.40A	1oxrA-5gjwF: undetectable	1oxrA-5gjwF: 7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T46_A_STIA3_2 (HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	VAL F 738 VAL F 801 TYR F 632 CYH F 509	None	1.26A	1t46A-5gjwF: undetectable	1t46A-5gjwF: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_A_BEZA352_0 (D-AMINO-ACID OXIDASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	LEU F 889 TYR F 895 ILE F1019 GLY F 859	None	0.94A	2du8A-5gjwF: undetectable	2du8A-5gjwF: 14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_B_BEZB1352_0 (D-AMINO-ACID OXIDASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	LEU F 889 TYR F 895 ILE F1019 GLY F 859	None	0.92A	2du8B-5gjwF: 2.6	2du8B-5gjwF: 14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJF_B_ADNB2002_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	GLU F 414 ASN F 424 PRO F 416 ALA F 420	None	1.05A	2ejfB-5gjwF: undetectable	2ejfB-5gjwF: 13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_A_ADNA1501_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	GLU F 414 ASN F 424 PRO F 416 ALA F 420	None	1.07A	2ejgA-5gjwF: undetectable	2ejgA-5gjwF: 12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_B_ADNB1502_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	GLU F 414 ASN F 424 PRO F 416 ALA F 420	None	1.11A	2ejgB-5gjwF: undetectable	2ejgB-5gjwF: 12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA802_1 (TRANSPORTER)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	ILE F 743 ARG F 707 ILE F 705 PHE F 686	None	1.13A	2q72A-5gjwF: undetectable	2q72A-5gjwF: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	ASP F 454 VAL F 461 TYR F 452 THR F 449 VAL F 489	None	1.24A	2x0yA-5gjwF: undetectable	2x0yA-5gjwF: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	MET F 404 ILE F 401 ASP F 261 SER F 265	None None None CA F1201 (-2.7A)	0.98A	2xytE-5gjwF: undetectable	2xytE-5gjwF: 11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	MET F 404 ILE F 401 ASP F 261 SER F 265	None None None CA F1201 (-2.7A)	1.01A	2xytH-5gjwF: undetectable	2xytH-5gjwF: 11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	MET F 404 ILE F 401 ASP F 261 SER F 265	None None None CA F1201 (-2.7A)	0.97A	2xytI-5gjwF: undetectable	2xytI-5gjwF: 11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y05_A_RALA801_1 (PROSTAGLANDIN REDUCTASE 1)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	TYR F 175 VAL F 168 TYR F 128 VAL F 181	None	1.08A	2y05A-5gjwF: undetectable 2y05B-5gjwF: undetectable	2y05A-5gjwF: 15.27 2y05B-5gjwF: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_B_SALB1305_1 (LYSR-TYPE REGULATORY PROTEIN)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 5	SER F 352 ARG F1056 PRO F1059 GLY F1058	None	1.36A	2y7kB-5gjwF: undetectable	2y7kB-5gjwF: 11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_A_ADNA1301_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 7	GLU F 414 ASN F 424 PRO F 416 ALA F 420	None	1.00A	2zgwA-5gjwF: undetectable	2zgwA-5gjwF: 13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_B_ADNB1302_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	GLU F 414 ASN F 424 PRO F 416 ALA F 420	None	1.02A	2zgwB-5gjwF: undetectable	2zgwB-5gjwF: 13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJ8_C_SPMC500_1 (DIAMINE ACETYLTRANSFERASE 1)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	ASP F 289 LEU F 432 ASP F 255 LEU F 346	None	1.25A	3bj8C-5gjwF: undetectable 3bj8D-5gjwF: undetectable	3bj8C-5gjwF: 9.35 3bj8D-5gjwF: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWC_A_SAMA501_0 (SPERMIDINE SYNTHASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	GLN F 981 HIS F 526 ILE F 534 GLY F 535 GLN F 530	None	0.98A	3bwcA-5gjwF: undetectable	3bwcA-5gjwF: 13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	LEU F 185 LEU F 182 VAL F 181 SER F 178 VAL F 168	None	1.30A	3m7rA-5gjwF: undetectable	3m7rA-5gjwF: 12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	TYR F 349 ASP F 255 ASP F 288	None	0.88A	3ou6B-5gjwF: undetectable	3ou6B-5gjwF: 11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RET_A_SALA201_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 10	VAL F 278 ALA F 323 VAL F 303 ILE F 327 ILE F 258	None	1.19A	3retA-5gjwF: undetectable 3retB-5gjwF: undetectable	3retA-5gjwF: 7.14 3retB-5gjwF: 7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_C_ACHC323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	GLU F 717 TYR F 66 LEU F 69 PHE F 714	None	0.93A	3rqwC-5gjwF: undetectable 3rqwD-5gjwF: undetectable	3rqwC-5gjwF: 14.83 3rqwD-5gjwF: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_I_ACHI323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	GLU F 717 TYR F 66 LEU F 69 PHE F 714	None	0.92A	3rqwI-5gjwF: undetectable 3rqwJ-5gjwF: undetectable	3rqwI-5gjwF: 14.83 3rqwJ-5gjwF: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_J_ACHJ323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	GLU F 717 TYR F 66 LEU F 69 PHE F 714	None	0.94A	3rqwF-5gjwF: undetectable 3rqwJ-5gjwF: undetectable	3rqwF-5gjwF: 14.83 3rqwJ-5gjwF: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_D_SUED1201_2 (NS3 PROTEASE, NS4A PROTEIN)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	TYR F 609 LEU F 502 LYS F 500	None	0.75A	3sueD-5gjwF: undetectable	3sueD-5gjwF: 11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WXO_A_NIZA804_1 (CATALASE-PEROXIDASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	ASN F 615 GLU F 89 ARG F 86	NAG F1205 (-1.9A) None None	0.90A	3wxoA-5gjwF: 0.5	3wxoA-5gjwF: 20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	SER F 884 MET F 851 VAL F1021 ARG F1004	None	1.15A	4lnwA-5gjwF: undetectable	4lnwA-5gjwF: 13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_1 (DIHYDROPTEROATE SYNTHASE DHPS)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	LYS F 318 ASN F 292 ASP F 322	None	0.81A	4o1eA-5gjwF: undetectable	4o1eA-5gjwF: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6X_I_HCYI900_2 (GLUCOCORTICOID RECEPTOR)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	MET F 796 MET F 864 TYR F 782	None	1.42A	4p6xI-5gjwF: undetectable	4p6xI-5gjwF: 12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	THR F 744 THR F 715 GLY F 742 GLY F 741	None	0.81A	4qvvK-5gjwF: undetectable 4qvvL-5gjwF: undetectable	4qvvK-5gjwF: 11.28 4qvvL-5gjwF: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	THR F 744 THR F 715 GLY F 742 GLY F 741	None	0.82A	4qvvY-5gjwF: undetectable 4qvvZ-5gjwF: undetectable	4qvvY-5gjwF: 11.28 4qvvZ-5gjwF: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y1D_D_DVAD5_0 (CYCLIC HEXAPEPTIDE CYC[NDPOPPKID] INTEGRASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	GLU F 753 LYS F 749 ASN F 754	None	1.03A	4y1dA-5gjwF: undetectable 4y1dD-5gjwF: undetectable	4y1dA-5gjwF: 9.58 4y1dD-5gjwF: 0.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE1_A_X2NA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	PHE F 877 GLY F 879 LEU F 856 PHE F 986 THR F 779	None	1.13A	4ze1A-5gjwF: undetectable	4ze1A-5gjwF: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HG0_A_SAMA301_0 (PANTOTHENATE SYNTHETASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	GLY F 249 VAL F 194 GLY F 464 THR F 449 GLN F 248	None	1.16A	5hg0A-5gjwF: undetectable	5hg0A-5gjwF: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ERYA404_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 6	ASP F 764 ARG F 769 TYR F 601 TYR F 782	None	1.13A	5iwuA-5gjwF: undetectable	5iwuA-5gjwF: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIW_B_OAQB302_0 (SULFOTRANSFERASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	PRO F 435 ILE F 359 PHE F 387 LEU F 285 THR F 284	None	1.28A	5tiwB-5gjwF: undetectable	5tiwB-5gjwF: 13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	3 / 3	TYR F 609 ARG F 607 THR F 589	None	1.00A	5z84J-5gjwF: undetectable	5z84J-5gjwF: 4.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E8Q_A_X2NA602_0 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	5 / 12	PHE F 877 GLY F 879 LEU F 856 PHE F 986 THR F 779	None	1.14A	6e8qA-5gjwF: undetectable	6e8qA-5gjwF: 6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GIQ_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5gjw	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 (Oryctolagus cuniculus)	4 / 8	ASP F 287 GLY F 537 ASN F 316 VAL F 319	None	0.84A	6giqL-5gjwF: undetectable 6giqP-5gjwF: undetectable 6giqT-5gjwF: undetectable	6giqL-5gjwF: 17.48 6giqP-5gjwF: 11.93 6giqT-5gjwF: 5.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FO4_B_SALB4005_1","XANTHINE DEHYDROGENASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 760;THR F 739;VAL F 738;ALA F 665","None","1.11A","1fo4B-5gjwF:undetectable","1fo4B-5gjwF:21.39"],["1NR6_A_DIFA501_1","CYTOCHROME P450 2C5","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"ALA F 712;GLY F 742;LEU F 683;LEU F 651;PHE F 686","None","1.08A","1nr6A-5gjwF:undetectable","1nr6A-5gjwF:18.30"],["1OXR_A_AINA141_1","PHOSPHOLIPASE A2 ISOFORM 3","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"LEU F  59;GLY F 713;ASP F 711;TYR F  63","None","1.40A","1oxrA-5gjwF:undetectable","1oxrA-5gjwF:7.04"],["1T46_A_STIA3_2","HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"VAL F 738;VAL F 801;TYR F 632;CYH F 509","None","1.26A","1t46A-5gjwF:undetectable","1t46A-5gjwF:14.16"],["2DU8_A_BEZA352_0","D-AMINO-ACID OXIDASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"LEU F 889;TYR F 895;ILE F1019;GLY F 859","None","0.94A","2du8A-5gjwF:undetectable","2du8A-5gjwF:14.47"],["2DU8_B_BEZB1352_0","D-AMINO-ACID OXIDASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"LEU F 889;TYR F 895;ILE F1019;GLY F 859","None","0.92A","2du8B-5gjwF:2.6","2du8B-5gjwF:14.47"],["2EJF_B_ADNB2002_1","235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 414;ASN F 424;PRO F 416;ALA F 420","None","1.05A","2ejfB-5gjwF:undetectable","2ejfB-5gjwF:13.11"],["2EJG_A_ADNA1501_1","235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 414;ASN F 424;PRO F 416;ALA F 420","None","1.07A","2ejgA-5gjwF:undetectable","2ejgA-5gjwF:12.93"],["2EJG_B_ADNB1502_1","235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 414;ASN F 424;PRO F 416;ALA F 420","None","1.11A","2ejgB-5gjwF:undetectable","2ejgB-5gjwF:12.93"],["2Q72_A_IXXA802_1","TRANSPORTER","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"ILE F 743;ARG F 707;ILE F 705;PHE F 686","None","1.13A","2q72A-5gjwF:undetectable","2q72A-5gjwF:18.63"],["2X0Y_A_X0TA1625_1","O-GLCNACASE NAGJ","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"ASP F 454;VAL F 461;TYR F 452;THR F 449;VAL F 489","None","1.24A","2x0yA-5gjwF:undetectable","2x0yA-5gjwF:19.66"],["2XYT_D_TC9D1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"MET F 404;ILE F 401;ASP F 261;SER F 265","None;None;None; CA F1201 (-2.7A)","0.98A","2xytE-5gjwF:undetectable","2xytE-5gjwF:11.44"],["2XYT_G_TC9G1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"MET F 404;ILE F 401;ASP F 261;SER F 265","None;None;None; CA F1201 (-2.7A)","1.01A","2xytH-5gjwF:undetectable","2xytH-5gjwF:11.44"],["2XYT_H_TC9H1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"MET F 404;ILE F 401;ASP F 261;SER F 265","None;None;None; CA F1201 (-2.7A)","0.97A","2xytI-5gjwF:undetectable","2xytI-5gjwF:11.44"],["2Y05_A_RALA801_1","PROSTAGLANDIN REDUCTASE 1;PROSTAGLANDIN REDUCTASE 1","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"TYR F 175;VAL F 168;TYR F 128;VAL F 181","None","1.08A","2y05A-5gjwF:undetectable;2y05B-5gjwF:undetectable","2y05A-5gjwF:15.27;2y05B-5gjwF:15.27"],["2Y7K_B_SALB1305_1","LYSR-TYPE REGULATORY PROTEIN","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"SER F 352;ARG F1056;PRO F1059;GLY F1058","None","1.36A","2y7kB-5gjwF:undetectable","2y7kB-5gjwF:11.95"],["2ZGW_A_ADNA1301_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 414;ASN F 424;PRO F 416;ALA F 420","None","1.00A","2zgwA-5gjwF:undetectable","2zgwA-5gjwF:13.11"],["2ZGW_B_ADNB1302_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 414;ASN F 424;PRO F 416;ALA F 420","None","1.02A","2zgwB-5gjwF:undetectable","2zgwB-5gjwF:13.11"],["3BJ8_C_SPMC500_1","DIAMINE ACETYLTRANSFERASE 1;DIAMINE ACETYLTRANSFERASE 1","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"ASP F 289;LEU F 432;ASP F 255;LEU F 346","None","1.25A","3bj8C-5gjwF:undetectable;3bj8D-5gjwF:undetectable","3bj8C-5gjwF:9.35;3bj8D-5gjwF:9.35"],["3BWC_A_SAMA501_0","SPERMIDINE SYNTHASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"GLN F 981;HIS F 526;ILE F 534;GLY F 535;GLN F 530","None","0.98A","3bwcA-5gjwF:undetectable","3bwcA-5gjwF:13.70"],["3M7R_A_VDXA425_1","VITAMIN D3 RECEPTOR","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"LEU F 185;LEU F 182;VAL F 181;SER F 178;VAL F 168","None","1.30A","3m7rA-5gjwF:undetectable","3m7rA-5gjwF:12.68"],["3OU6_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"TYR F 349;ASP F 255;ASP F 288","None","0.88A","3ou6B-5gjwF:undetectable","3ou6B-5gjwF:11.62"],["3RET_A_SALA201_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB;SALICYLATE BIOSYNTHESIS PROTEIN PCHB","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"VAL F 278;ALA F 323;VAL F 303;ILE F 327;ILE F 258","None","1.19A","3retA-5gjwF:undetectable;3retB-5gjwF:undetectable","3retA-5gjwF:7.14;3retB-5gjwF:7.14"],["3RQW_C_ACHC323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 717;TYR F  66;LEU F  69;PHE F 714","None","0.93A","3rqwC-5gjwF:undetectable;3rqwD-5gjwF:undetectable","3rqwC-5gjwF:14.83;3rqwD-5gjwF:14.83"],["3RQW_I_ACHI323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 717;TYR F  66;LEU F  69;PHE F 714","None","0.92A","3rqwI-5gjwF:undetectable;3rqwJ-5gjwF:undetectable","3rqwI-5gjwF:14.83;3rqwJ-5gjwF:14.83"],["3RQW_J_ACHJ323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"GLU F 717;TYR F  66;LEU F  69;PHE F 714","None","0.94A","3rqwF-5gjwF:undetectable;3rqwJ-5gjwF:undetectable","3rqwF-5gjwF:14.83;3rqwJ-5gjwF:14.83"],["3SUE_D_SUED1201_2","NS3 PROTEASE, NS4A PROTEIN","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"TYR F 609;LEU F 502;LYS F 500","None","0.75A","3sueD-5gjwF:undetectable","3sueD-5gjwF:11.71"],["3WXO_A_NIZA804_1","CATALASE-PEROXIDASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"ASN F 615;GLU F  89;ARG F  86","NAG F1205 (-1.9A);None;None","0.90A","3wxoA-5gjwF:0.5","3wxoA-5gjwF:20.14"],["4LNW_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"SER F 884;MET F 851;VAL F1021;ARG F1004","None","1.15A","4lnwA-5gjwF:undetectable","4lnwA-5gjwF:13.38"],["4O1E_A_C2FA3000_1","DIHYDROPTEROATE SYNTHASE DHPS","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"LYS F 318;ASN F 292;ASP F 322","None","0.81A","4o1eA-5gjwF:undetectable","4o1eA-5gjwF:14.55"],["4P6X_I_HCYI900_2","GLUCOCORTICOID RECEPTOR","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"MET F 796;MET F 864;TYR F 782","None","1.42A","4p6xI-5gjwF:undetectable","4p6xI-5gjwF:12.76"],["4QVV_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"THR F 744;THR F 715;GLY F 742;GLY F 741","None","0.81A","4qvvK-5gjwF:undetectable;4qvvL-5gjwF:undetectable","4qvvK-5gjwF:11.28;4qvvL-5gjwF:11.48"],["4QVV_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"THR F 744;THR F 715;GLY F 742;GLY F 741","None","0.82A","4qvvY-5gjwF:undetectable;4qvvZ-5gjwF:undetectable","4qvvY-5gjwF:11.28;4qvvZ-5gjwF:11.48"],["4Y1D_D_DVAD5_0","CYCLIC HEXAPEPTIDE CYC[NDPOPPKID];INTEGRASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"GLU F 753;LYS F 749;ASN F 754","None","1.03A","4y1dA-5gjwF:undetectable;4y1dD-5gjwF:undetectable","4y1dA-5gjwF:9.58;4y1dD-5gjwF:0.58"],["4ZE1_A_X2NA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"PHE F 877;GLY F 879;LEU F 856;PHE F 986;THR F 779","None","1.13A","4ze1A-5gjwF:undetectable","4ze1A-5gjwF:20.16"],["5HG0_A_SAMA301_0","PANTOTHENATE SYNTHETASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"GLY F 249;VAL F 194;GLY F 464;THR F 449;GLN F 248","None","1.16A","5hg0A-5gjwF:undetectable","5hg0A-5gjwF:13.60"],["5IWU_A_ERYA404_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"ASP F 764;ARG F 769;TYR F 601;TYR F 782","None","1.13A","5iwuA-5gjwF:undetectable","5iwuA-5gjwF:14.71"],["5TIW_B_OAQB302_0","SULFOTRANSFERASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"PRO F 435;ILE F 359;PHE F 387;LEU F 285;THR F 284","None","1.28A","5tiwB-5gjwF:undetectable","5tiwB-5gjwF:13.21"],["5Z84_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",3,"TYR F 609;ARG F 607;THR F 589","None","1.00A","5z84J-5gjwF:undetectable","5z84J-5gjwF:4.58"],["6E8Q_A_X2NA602_0","LANOSTEROL 14-ALPHA DEMETHYLASE","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",5,"PHE F 877;GLY F 879;LEU F 856;PHE F 986;THR F 779","None","1.14A","6e8qA-5gjwF:undetectable","6e8qA-5gjwF:6.19"],["6GIQ_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5gjw","VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2\/DELTA-1","Oryctolagus cuniculus",4,"ASP F 287;GLY F 537;ASN F 316;VAL F 319","None","0.84A","6giqL-5gjwF:undetectable;6giqP-5gjwF:undetectable;6giqT-5gjwF:undetectable","6giqL-5gjwF:17.48;6giqP-5gjwF:11.93;6giqT-5gjwF:5.10"]]