SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 8 SER A 213
ILE A 212
GLU A 261
LEU A 265
 None
 0.86A 1eupA-5gjyA:
undetectable		 1eupA-5gjyA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		3 / 3 TRP A 167
GLU A  65
TYR A  61
 None
 0.96A 2a3aA-5gjyA:
undetectable		 2a3aA-5gjyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 5 ALA A 137
GLN A 140
ILE A 141
ARG A 144
 None
 0.90A 2z0aA-5gjyA:
undetectable		 2z0aA-5gjyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 5 ALA A 139
GLN A 140
ILE A 141
ARG A 144
 None
 1.49A 2z0aA-5gjyA:
undetectable		 2z0aA-5gjyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 6 ARG A  84
ARG A  77
ASP A  81
VAL A  15
 None
 1.22A 4xqeA-5gjyA:
undetectable		 4xqeA-5gjyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5gjy MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 6 ARG A  84
ARG A  77
ASP A  81
VAL A  15
 None
 1.19A 4xqeB-5gjyA:
undetectable		 4xqeB-5gjyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 5gjy BETA-2-MICROGLOBULIN
(Anas
platyrhynchos) 		3 / 3 VAL B  82
THR B  84
ARG B  99
 None
 0.67A 5b2sB-5gjyB:
undetectable		 5b2sB-5gjyB:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 5gjy BETA-2-MICROGLOBULIN
(Anas
platyrhynchos) 		3 / 3 VAL B  82
THR B  84
ARG B  99
 None
 0.67A 5b2tB-5gjyB:
undetectable		 5b2tB-5gjyB:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 5gjy BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Anas
platyrhynchos) 		4 / 8 TRP A 243
GLN B  13
ALA A 244
SER A 201
 None
 1.04A 5km8A-5gjyA:
undetectable
5km8B-5gjyA:
undetectable		 5km8A-5gjyA:
20.37
5km8B-5gjyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5gjy BETA-2-MICROGLOBULIN
(Anas
platyrhynchos) 		3 / 3 THR B  84
SER B  97
ASP B  41
 None
 0.73A 5kvaB-5gjyB:
undetectable		 5kvaB-5gjyB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5gjy MHC CLASS I ANTIGEN
BETA-2-MICROGLOBULIN
(Anas
platyrhynchos;
Anas
platyrhynchos) 		5 / 11 VAL A  31
GLY A  33
SER B  60
SER A   7
LEU A   8
 None
 1.17A 5x6yA-5gjyA:
undetectable		 5x6yA-5gjyA:
17.50