SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		4 / 7 PRO B 129
ALA B 131
SER B 143
ALA B 145
 None
 1.06A 1k5qA-5gkaB:
undetectable
1k5qB-5gkaB:
undetectable		 1k5qA-5gkaB:
21.65
1k5qB-5gkaB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 5gka CAPSID PROTEIN VP0
GENOME POLYPROTEIN
(Aichivirus
A) 		3 / 3 PHE C  48
VAL C  42
TRP B  73
 None
 0.74A 2cc8A-5gkaC:
undetectable		 2cc8A-5gkaC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 5gka CAPSID PROTEIN VP0
GENOME POLYPROTEIN
(Aichivirus
A) 		3 / 3 PHE C  48
VAL C  42
TRP B  73
 None
 0.73A 2ccbA-5gkaC:
undetectable		 2ccbA-5gkaC:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 5gka CAPSID PROTEIN VP0
GENOME POLYPROTEIN
(Aichivirus
A) 		3 / 3 PHE C  48
VAL C  42
TRP B  73
 None
 0.71A 2vx9A-5gkaC:
undetectable		 2vx9A-5gkaC:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		5 / 12 HIS B 267
ASN B 306
LEU B 349
LEU B 339
GLY B 269
 None
 1.26A 3g1uA-5gkaB:
undetectable		 3g1uA-5gkaB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5gka GENOME POLYPROTEIN
(Aichivirus
A) 		5 / 12 ILE C 155
VAL C  75
ILE C  80
ILE C 205
SER C 206
 None
 1.03A 3kpdC-5gkaC:
undetectable		 3kpdC-5gkaC:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		3 / 3 LEU B 207
TRP B 217
GLY B 198
 None
 0.61A 3l35A-5gkaB:
undetectable
3l35H-5gkaB:
undetectable		 3l35A-5gkaB:
7.74
3l35H-5gkaB:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		3 / 3 LEU B 207
TRP B 217
GLY B 198
 None
 0.62A 3l35B-5gkaB:
undetectable
3l35K-5gkaB:
undetectable		 3l35B-5gkaB:
7.74
3l35K-5gkaB:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		5 / 12 GLN B 334
ARG B 288
ASN B 290
GLY B 190
ALA B 283
 None
 1.23A 3v3oA-5gkaB:
undetectable		 3v3oA-5gkaB:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 5gka GENOME POLYPROTEIN
(Aichivirus
A) 		5 / 9 ALA C  56
ALA C  85
GLY C  84
ILE C  80
ILE C 205
 None
 0.99A 4eatB-5gkaC:
undetectable		 4eatB-5gkaC:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		3 / 3 LEU B 228
MET B 199
TYR B 236
 None
 0.96A 4p6xG-5gkaB:
undetectable		 4p6xG-5gkaB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 5gka GENOME POLYPROTEIN
(Aichivirus
A) 		4 / 7 ALA C 103
LEU C 105
LEU C 106
ILE C 205
 None
 0.71A 4ubsA-5gkaC:
undetectable		 4ubsA-5gkaC:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		4 / 4 LEU B 325
GLY B 324
SER B 323
SER B 249
 None
 1.24A 5uunA-5gkaB:
undetectable		 5uunA-5gkaB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		4 / 4 LEU B 325
GLY B 324
SER B 323
SER B 249
 None
 1.15A 5uunB-5gkaB:
undetectable		 5uunB-5gkaB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5gka CAPSID PROTEIN VP0
(Aichivirus
A) 		5 / 12 VAL B 261
LEU B 349
SER B 352
PHE B 331
VAL B 335
 None
 1.14A 6a94B-5gkaB:
undetectable		 6a94B-5gkaB:
20.33