SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gkb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
PRO A  38
THR A  53
ARG A 125
TYR A 127
 None
 0.80A 1cbrA-5gkbA:
18.0		 1cbrA-5gkbA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
PRO A  38
THR A  53
ARG A 125
TYR A 127
 None
 0.80A 1cbrB-5gkbA:
18.0		 1cbrB-5gkbA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
TYR A  19
LEU A  36
PRO A  38
THR A  53
 None
 1.00A 1mx8A-5gkbA:
17.2		 1mx8A-5gkbA:
35.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
VAL A  25
SER A  55
ARG A 125
TYR A 127
 None
 0.72A 2qm9A-5gkbA:
20.6		 2qm9A-5gkbA:
42.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		4 / 4 TYR A  19
MET A  20
PRO A  38
ILE A 103
 None
 0.43A 2qm9A-5gkbA:
20.6		 2qm9A-5gkbA:
42.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		7 / 12 PHE A  16
TYR A  19
VAL A  25
SER A  55
ILE A 103
ARG A 125
TYR A 127
 None
 0.72A 2qm9B-5gkbA:
21.1		 2qm9B-5gkbA:
42.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		7 / 12 PHE A  16
MET A  20
VAL A  25
PRO A  38
CYH A 123
ARG A 125
TYR A 127
 None
 1.21A 3p6gA-5gkbA:
20.4		 3p6gA-5gkbA:
47.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		8 / 12 PHE A  16
MET A  20
VAL A  25
PRO A  38
ILE A 103
ARG A 105
ARG A 125
TYR A 127
 None
 0.66A 3p6gA-5gkbA:
20.4		 3p6gA-5gkbA:
47.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 7 PHE A  16
MET A  20
ILE A 103
ARG A 125
TYR A 127
 None
 0.53A 3p6hA-5gkbA:
20.3		 3p6hA-5gkbA:
47.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 6 TYR A  19
GLU A  72
THR A  74
LEU A  75
GLN A  95
 None
 0.97A 4qztA-5gkbA:
19.9		 4qztA-5gkbA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		4 / 5 TYR A  19
GLU A  72
LEU A  75
GLN A  95
 None
 0.86A 4qztB-5gkbA:
20.0		 4qztB-5gkbA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 6 TYR A  19
GLU A  72
THR A  74
GLN A  95
LEU A 116
 None
 0.99A 4qzuC-5gkbA:
19.9		 4qzuC-5gkbA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
TYR A  19
VAL A  25
PRO A  38
SER A  55
 None
 0.70A 5hbsA-5gkbA:
19.6		 5hbsA-5gkbA:
35.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		5 / 12 PHE A  16
TYR A  19
LEU A  36
PRO A  38
SER A  55
 None
 0.80A 5ljcA-5gkbA:
19.5		 5ljcA-5gkbA:
36.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B
(Drosophila
melanogaster) 		4 / 5 PHE A  64
THR A  92
GLU A  72
ASN A  79
 None
 1.33A 5ybbA-5gkbA:
undetectable		 5ybbA-5gkbA:
11.76