SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  97
ARG A 104
ALA A 106
LEU A 125
ALA A 123
 None
 0.98A 1fk6A-5gl6A:
undetectable		 1fk6A-5gl6A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ASP A  94
LYS A 110
ARG A 124
 None
 0.56A 1ra8A-5gl6A:
undetectable		 1ra8A-5gl6A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ALA A 123
ALA A 173
ARG A 107
LEU A 170
LEU A 113
 None
 1.12A 2bxqA-5gl6A:
undetectable		 2bxqA-5gl6A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		4 / 6 THR A  89
VAL A  88
LEU A  58
SER A  67
 None
 1.26A 3b6rB-5gl6A:
undetectable		 3b6rB-5gl6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  88
VAL A  19
LEU A  22
GLY A  72
LEU A  86
 None
 1.03A 3n8wA-5gl6A:
undetectable		 3n8wA-5gl6A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		6 / 12 VAL A  88
VAL A  19
LEU A  22
GLY A  72
ALA A  70
LEU A  86
 None
 1.23A 3n8zA-5gl6A:
undetectable		 3n8zA-5gl6A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 121
ILE A 153
ALA A 144
VAL A 136
GLY A 126
 None
 1.16A 4hfpD-5gl6A:
undetectable		 4hfpD-5gl6A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ASP A  55
GLY A  57
LEU A  58
LEU A  66
ALA A  62
 None
 1.12A 5dqfA-5gl6A:
undetectable		 5dqfA-5gl6A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  19
LEU A  22
GLY A  72
ALA A  70
LEU A  86
 None
 1.17A 5ikrA-5gl6A:
undetectable		 5ikrA-5gl6A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A  86
LEU A  66
ALA A  70
LEU A  73
 None
 0.82A 5vkqB-5gl6A:
undetectable
5vkqC-5gl6A:
undetectable		 5vkqB-5gl6A:
7.55
5vkqC-5gl6A:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		4 / 6 PHE A 103
ARG A 107
LEU A 125
ALA A 156
 None
 1.06A 6b89B-5gl6A:
2.4		 6b89B-5gl6A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		4 / 7 PHE A 103
ARG A 107
LEU A 125
ALA A 156
 None
 1.15A 6b89A-5gl6A:
2.2		 6b89A-5gl6A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5gl6 RIBOSOME MATURATION
FACTOR RIMP
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ALA A  52
GLY A  57
LEU A  58
ALA A  62
 None
 0.79A 6mdqA-5gl6A:
undetectable		 6mdqA-5gl6A:
17.20