SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 8 ILE A 247
ASN A 214
GLY A 248
LEU A 194
 None
 0.92A 1dzmA-5gl9A:
2.9		 1dzmA-5gl9A:
20.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 None
 0.24A 1ghmA-5gl9A:
38.4		 1ghmA-5gl9A:
33.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 8 ASN A 136
LEU A  76
LYS A 234
LEU A 169
 None
 1.12A 1hk3A-5gl9A:
undetectable		 1hk3A-5gl9A:
17.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
LYS A 234
GLY A 236
 None
 0.35A 1i2wA-5gl9A:
41.4		 1i2wA-5gl9A:
43.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
GLY A 236
ARG A 220
 None
 1.08A 1i2wB-5gl9A:
41.3		 1i2wB-5gl9A:
43.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
THR A 216
GLY A 236
 None
 0.36A 1i2wB-5gl9A:
41.3		 1i2wB-5gl9A:
43.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		11 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
 0.42A 1ymxA-5gl9A:
45.1		 1ymxA-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
 0.36A 1ymxB-5gl9A:
45.0		 1ymxB-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 CYH A  69
TYR A 105
THR A 216
THR A 235
 None
 0.76A 1ymxB-5gl9A:
45.0		 1ymxB-5gl9A:
57.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 165
GLN A 146
PRO A 145
 None
 0.85A 2qhfA-5gl9A:
undetectable		 2qhfA-5gl9A:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 7 ARG A  65
GLU A  64
ALA A 185
ALA A 184
 None
 0.94A 2zgwA-5gl9A:
undetectable		 2zgwA-5gl9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 ALA A 283
PRO A  67
PHE A  66
GLY A 244
THR A 243
THR A 266
 None
 1.35A 2zifA-5gl9A:
undetectable		 2zifA-5gl9A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 THR A 109
MET A 117
ALA A 140
VAL A 148
LEU A  76
 None
 1.12A 3a51E-5gl9A:
undetectable		 3a51E-5gl9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 VAL A 262
VAL A 263
PHE A  68
ARG A 222
 None
 1.19A 3bjwH-5gl9A:
undetectable		 3bjwH-5gl9A:
14.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 GLY A 236
TYR A 105
SER A 130
THR A 216
LYS A 234
GLY A 238
 None
 1.49A 3hlwA-5gl9A:
45.1		 3hlwA-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
 None
 0.47A 3hlwA-5gl9A:
45.1		 3hlwA-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 None
 0.41A 3hlwB-5gl9A:
45.0		 3hlwB-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 CYH A  69
LYS A  73
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
GLY A 238
ASP A 240
 None
 0.30A 3huoA-5gl9A:
45.1		 3huoA-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 6 THR A  52
ARG A 191
GLY A 196
ALA A 257
PRO A 258
 None
 0.65A 3huoA-5gl9A:
45.1		 3huoA-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 CYH A  69
LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
 0.26A 3huoB-5gl9A:
44.8		 3huoB-5gl9A:
57.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
LYS A  73
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 0.80A 3mzeA-5gl9A:
21.7		 3mzeA-5gl9A:
22.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		11 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.42A 3ny4A-5gl9A:
40.6		 3ny4A-5gl9A:
46.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 GLY A 236
SER A 130
ASN A 170
LYS A 234
GLY A 238
ASP A 240
 None
 1.48A 3q07A-5gl9A:
45.0		 3q07A-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
 0.33A 3q07A-5gl9A:
45.0		 3q07A-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 CYH A  69
TYR A 105
THR A 171
THR A 235
 None
 0.69A 3q07A-5gl9A:
45.0		 3q07A-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 GLY A 236
SER A 130
ASN A 170
LYS A 234
GLY A 238
ASP A 240
 None
 1.48A 3q07B-5gl9A:
44.8		 3q07B-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
GLY A 238
ASP A 240
 None
 0.36A 3q07B-5gl9A:
44.8		 3q07B-5gl9A:
57.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 CYH A  69
TYR A 105
THR A 171
THR A 235
 None
 0.72A 3q07B-5gl9A:
44.8		 3q07B-5gl9A:
57.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 GLY A  86
ASP A  87
ARG A  83
GLN A 206
 None
 1.01A 3qx3B-5gl9A:
undetectable		 3qx3B-5gl9A:
16.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 None
 0.15A 3sh8A-5gl9A:
40.0		 3sh8A-5gl9A:
43.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
TYR A 105
SER A 130
ASN A 132
LYS A 234
THR A 235
 None
 0.64A 3sh8A-5gl9A:
40.0		 3sh8A-5gl9A:
43.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 None
 0.23A 3sh8B-5gl9A:
39.9		 3sh8B-5gl9A:
43.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
 None
 0.40A 4euzA-5gl9A:
42.7		 4euzA-5gl9A:
51.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 10 TYR A 105
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
 None
 0.68A 4fh2A-5gl9A:
35.9		 4fh2A-5gl9A:
46.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 10 TYR A 105
SER A 130
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 1.40A 4fh2A-5gl9A:
35.9		 4fh2A-5gl9A:
46.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 LEU A 122
CYH A 123
ALA A  79
GLY A 144
LEU A 142
 None
 1.17A 4j7xB-5gl9A:
undetectable		 4j7xB-5gl9A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 6 ARG A 161
ASP A 176
ASP A 163
ARG A 178
 None
 1.41A 4kcnA-5gl9A:
undetectable		 4kcnA-5gl9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 6 ARG A 161
ASP A 176
ASP A 163
ARG A 178
 None
 1.38A 4kcnB-5gl9A:
undetectable		 4kcnB-5gl9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 8 ARG A  65
SER A 189
ALA A 152
ARG A 153
 None
 1.09A 4lv9A-5gl9A:
undetectable
4lv9B-5gl9A:
undetectable		 4lv9A-5gl9A:
19.84
4lv9B-5gl9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 ASP A 276
ALA A 283
GLY A 244
SER A 281
ASP A 233
 None
 1.15A 4mm8A-5gl9A:
undetectable		 4mm8A-5gl9A:
18.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.54A 4n9kA-5gl9A:
41.7		 4n9kA-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 SER A  70
TYR A 105
SER A 130
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 1.14A 4n9kA-5gl9A:
41.7		 4n9kA-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.25A 4n9kB-5gl9A:
41.7		 4n9kB-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 None
 0.55A 4pm5A-5gl9A:
45.0		 4pm5A-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
 None
 0.86A 4pm5A-5gl9A:
45.0		 4pm5A-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
 None
 0.60A 4pm7A-5gl9A:
45.0		 4pm7A-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
 None
 0.88A 4pm7A-5gl9A:
45.0		 4pm7A-5gl9A:
57.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
GLY A 238
 None
 0.72A 4pm9A-5gl9A:
44.9		 4pm9A-5gl9A:
57.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 224
ASP A 276
ILE A 279
ALA A 282
PHE A  47
 None
 1.13A 4u8vB-5gl9A:
2.5		 4u8vB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 224
ASP A 276
ILE A 279
PHE A  47
VAL A 263
 None
 1.14A 4u8vB-5gl9A:
2.5		 4u8vB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 224
ASP A 276
ILE A 279
ALA A 282
PHE A  47
 None
 1.13A 4u8yB-5gl9A:
undetectable		 4u8yB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		3 / 3 ASP A 233
ASN A 245
PHE A  72
 None
 0.71A 5dsgB-5gl9A:
undetectable		 5dsgB-5gl9A:
21.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.30A 5ghyA-5gl9A:
41.5		 5ghyA-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		6 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.30A 5ghyB-5gl9A:
41.6		 5ghyB-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 11 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.56A 5ghzA-5gl9A:
41.6		 5ghzA-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 11 SER A  70
TYR A 105
SER A 130
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 1.17A 5ghzA-5gl9A:
41.6		 5ghzA-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 10 SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 None
 0.55A 5ghzB-5gl9A:
41.7		 5ghzB-5gl9A:
43.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		7 / 10 SER A  70
TYR A 105
SER A 130
ASN A 132
THR A 235
GLY A 236
ARG A 220
 None
 1.17A 5ghzB-5gl9A:
41.7		 5ghzB-5gl9A:
43.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 7 THR A 149
PHE A  72
ASP A 179
LEU A 169
 None
 1.21A 5uxcA-5gl9A:
undetectable		 5uxcA-5gl9A:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		5 / 12 ALA A 280
VAL A 225
VAL A 231
ASP A 233
GLY A 248
 None
 1.24A 5x24A-5gl9A:
undetectable		 5x24A-5gl9A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		12 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.41A 6b5yB-5gl9A:
41.1		 6b5yB-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		11 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.42A 6b5yD-5gl9A:
41.2		 6b5yD-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		11 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.32A 6b68B-5gl9A:
41.2		 6b68B-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.37A 6b68D-5gl9A:
41.1		 6b68D-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.31A 6b69A-5gl9A:
41.1
6b69B-5gl9A:
41.0		 6b69A-5gl9A:
18.28
6b69B-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		11 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
 None
 0.25A 6b69D-5gl9A:
40.9		 6b69D-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		12 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.35A 6b6aB-5gl9A:
41.2		 6b6aB-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 SER A  70
SER A 130
ASN A 170
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.28A 6b6aD-5gl9A:
41.2		 6b6aD-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 SER A  70
SER A 130
ASN A 170
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
 None
 0.31A 6b6cA-5gl9A:
41.1		 6b6cA-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 CYH A  69
SER A  70
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
 None
 0.29A 6b6dA-5gl9A:
40.7		 6b6dA-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		9 / 12 CYH A  69
SER A  70
SER A 130
THR A 216
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
 None
 0.49A 6b6dA-5gl9A:
40.7		 6b6dA-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
ARG A 220
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
 None
 0.30A 6b6eA-5gl9A:
40.9		 6b6eA-5gl9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		10 / 12 CYH A  69
SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
THR A 237
GLY A 238
ASP A 240
 None
 0.39A 6b6fA-5gl9A:
40.7		 6b6fA-5gl9A:
18.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		8 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
GLY A 238
 None
 0.52A 6c79A-5gl9A:
44.7		 6c79A-5gl9A:
48.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 GLY A 196
ASP A 197
ARG A 191
ARG A 192
 None
 1.38A 6dwdB-5gl9A:
undetectable
6dwdD-5gl9A:
undetectable		 6dwdB-5gl9A:
20.72
6dwdD-5gl9A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5gl9 BETA-LACTAMASE
(Burkholderia
thailandensis) 		4 / 5 ARG A 191
ARG A 192
GLY A 196
ASP A 197
 None
 1.30A 6dwjB-5gl9A:
undetectable
6dwjD-5gl9A:
undetectable		 6dwjB-5gl9A:
20.72
6dwjD-5gl9A:
20.72