SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA8_0
(GRAMICIDIN A)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		4 / 4 GLY A  72
VAL A 106
TRP A 170
TRP A 174
 None
 1.11A 1magA-5glyA:
undetectable		 1magA-5glyA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB8_0
(GRAMICIDIN A)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		4 / 4 GLY A  72
VAL A 106
TRP A 170
TRP A 174
 None
 1.11A 1magB-5glyA:
undetectable		 1magB-5glyA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		4 / 7 ASP A 115
SER A 118
SER A   7
ASP A 179
 None
None
None
CTR  A 302 (-2.6A)
 1.33A 3bc9A-5glyA:
undetectable		 3bc9A-5glyA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		3 / 3 GLY A 129
GLY A 145
GLY A 150
 CTR  A 302 (-3.5A)
None
None
 0.31A 3bogC-5glyA:
undetectable		 3bogC-5glyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		3 / 3 GLY A 129
GLY A 145
GLY A 150
 CTR  A 302 (-3.5A)
None
None
 0.30A 3bogD-5glyA:
undetectable		 3bogD-5glyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		5 / 12 LEU A 143
SER A 159
PHE A 160
ILE A 151
GLY A 128
 None
 1.19A 3kk6B-5glyA:
undetectable		 3kk6B-5glyA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		5 / 10 PHE A 183
PHE A  95
ALA A  74
THR A  76
ILE A  78
 None
 1.34A 3t3qC-5glyA:
undetectable		 3t3qC-5glyA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		5 / 10 PHE A 183
PHE A  95
ALA A  74
THR A  76
ILE A  78
 None
 1.36A 3t3qD-5glyA:
undetectable		 3t3qD-5glyA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		3 / 3 GLN A  38
ASP A  59
GLN A  60
 None
 0.74A 4aztA-5glyA:
undetectable		 4aztA-5glyA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		4 / 7 PHE A 140
ALA A  58
THR A  61
LEU A 143
 None
 1.08A 4ejgA-5glyA:
undetectable		 4ejgA-5glyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		5 / 11 GLY A 199
ALA A  24
VAL A  30
PHE A  73
ILE A 194
 None
 1.12A 4j4vA-5glyA:
undetectable		 4j4vA-5glyA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN
(Thielavia
terrestris) 		5 / 12 GLY A 129
GLY A 149
ALA A  75
THR A 110
ALA A 124
 CTR  A 302 (-3.5A)
CTR  A 302 (-3.7A)
CTT  A 301 (-3.5A)
None
None
 1.15A 4uckB-5glyA:
undetectable		 4uckB-5glyA:
17.66