SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		7 / 12 PHE A 114
GLY A 115
GLY A 120
ILE A 135
SER A 143
LEU A 144
ALA A 149
 None
 0.71A 1v2xA-5gmbA:
18.1		 1v2xA-5gmbA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 11 THR A  79
GLY A 115
GLY A 120
LEU A 144
ALA A 149
 None
 0.59A 1x7pA-5gmbA:
18.4
1x7pB-5gmbA:
18.6		 1x7pA-5gmbA:
22.34
1x7pB-5gmbA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		6 / 10 THR A  79
GLY A 115
GLY A 120
ILE A 135
LEU A 144
ALA A 149
 None
 0.72A 1x7pA-5gmbA:
18.4
1x7pB-5gmbA:
18.6		 1x7pA-5gmbA:
22.34
1x7pB-5gmbA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		4 / 8 SER A  74
LEU A 101
LEU A   2
LEU A  30
 None
 0.85A 2bfpA-5gmbA:
undetectable		 2bfpA-5gmbA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		4 / 8 SER A  74
LEU A 101
LEU A   2
LEU A  30
 None
 0.90A 2bfpD-5gmbA:
undetectable		 2bfpD-5gmbA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		6 / 12 GLY A  19
GLY A  16
HIS A  14
THR A  54
ALA A  53
ALA A  21
 None
 1.48A 2gluB-5gmbA:
undetectable		 2gluB-5gmbA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  35
ALA A  21
GLY A  19
PHE A  41
 None
 0.91A 2wq5A-5gmbA:
undetectable		 2wq5A-5gmbA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		7 / 11 THR A  79
ALA A  81
GLY A 115
GLY A 120
ILE A 135
LEU A 144
ALA A 149
 None
 0.73A 3dcmX-5gmbA:
15.3		 3dcmX-5gmbA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  81
GLY A 115
ILE A 135
SER A 143
LEU A 144
 None
 0.62A 3gyqA-5gmbA:
16.4
3gyqB-5gmbA:
16.4		 3gyqA-5gmbA:
23.16
3gyqB-5gmbA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  17
GLY A 115
GLY A 120
ILE A 135
ASN A 145
 None
 0.60A 3nk7A-5gmbA:
16.7		 3nk7A-5gmbA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		6 / 12 ASN A  17
PHE A 114
GLY A 115
GLY A 120
ILE A 135
LEU A 144
 None
 0.66A 3nk7B-5gmbA:
16.6		 3nk7B-5gmbA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 115
GLU A 117
GLY A 120
ILE A 135
LEU A 144
 None
 0.96A 3nk7B-5gmbA:
16.6		 3nk7B-5gmbA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  56
ALA A  53
ALA A  46
LEU A  35
LEU A   9
 None
 1.11A 3uvvA-5gmbA:
undetectable		 3uvvA-5gmbA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  20
ALA A 147
VAL A 150
LEU A   9
ILE A  56
 None
 1.14A 4pd5A-5gmbA:
undetectable		 4pd5A-5gmbA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  20
ALA A 147
VAL A 150
LEU A   9
ILE A  56
 None
 1.23A 4pd9A-5gmbA:
undetectable		 4pd9A-5gmbA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 133
ILE A   5
VAL A   7
LEU A 146
PHE A 114
 None
 1.28A 4y0pA-5gmbA:
undetectable		 4y0pA-5gmbA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 115
ILE A 135
SER A 143
LEU A 144
LEU A 146
ALA A 149
 None
 0.65A 5l0zA-5gmbA:
18.1		 5l0zA-5gmbA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		7 / 12 THR A  79
GLY A 115
GLY A 120
ILE A 135
LEU A 144
LEU A 146
ALA A 149
 None
 0.52A 5l0zA-5gmbA:
18.1		 5l0zA-5gmbA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		8 / 10 THR A  79
GLY A 115
GLY A 120
ILE A 135
SER A 143
LEU A 144
LEU A 146
ALA A 149
 None
 0.65A 5l0zB-5gmbA:
7.2		 5l0zB-5gmbA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5gmb TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  57
ALA A  50
LEU A  35
THR A  12
 None
 0.92A 6f88B-5gmbA:
undetectable		 6f88B-5gmbA:
20.89