SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 179
LEU A 155
ASN A 182
LEU A 139
LEU A 168
 None
 1.38A 1a28B-5gmhA:
undetectable		 1a28B-5gmhA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 SER A 490
LEU A 519
LEU A 500
LEU A 428
ASP A 427
 NAG  A 902 (-3.7A)
None
None
None
SO4  A 920 (-4.5A)
 1.42A 1e7wA-5gmhA:
undetectable		 1e7wA-5gmhA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 8 SER A 122
ARG A 121
PHE A 123
GLY A 145
 None
 0.91A 1fapB-5gmhA:
undetectable		 1fapB-5gmhA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 8 ASP A 287
PHE A 245
ASN A 284
LEU A 295
 None
 1.09A 1lhvA-5gmhA:
undetectable		 1lhvA-5gmhA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 11 LEU A 168
ILE A 195
GLU A 141
LEU A 155
LEU A 179
 None
 1.15A 1mrqA-5gmhA:
undetectable		 1mrqA-5gmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 MET A 603
ASN A 604
GLY A 628
LEU A 631
LEU A 655
 None
 1.08A 1p93C-5gmhA:
undetectable		 1p93C-5gmhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 548
LEU A 547
PHE A 549
ILE A 508
LEU A 533
 NAG  A 902 (-3.9A)
None
None
None
None
 1.03A 1rx3A-5gmhA:
undetectable		 1rx3A-5gmhA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 179
LEU A 155
ASN A 182
LEU A 139
LEU A 168
 None
 1.48A 1sqnA-5gmhA:
undetectable		 1sqnA-5gmhA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 HIS A 298
ASP A 213
ASN A 215
 None
None
NAG  A 903 ( 1.9A)
 0.87A 1wg8B-5gmhA:
undetectable		 1wg8B-5gmhA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 PHE A 466
PHE A 349
PHE A 351
 None
 0.69A 2od9A-5gmhA:
undetectable		 2od9A-5gmhA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 548
LEU A 547
PHE A 549
ILE A 508
LEU A 533
 NAG  A 902 (-3.9A)
None
None
None
None
 1.13A 2oipA-5gmhA:
undetectable		 2oipA-5gmhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 PRO A 102
ASN A 159
ARG A 115
 None
 0.77A 2qeuB-5gmhA:
undetectable		 2qeuB-5gmhA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 PHE A 466
PHE A 349
PHE A 351
 None
 0.69A 2qqgA-5gmhA:
undetectable		 2qqgA-5gmhA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 179
LEU A 155
ASN A 182
LEU A 139
LEU A 168
 None
 1.47A 2w8yB-5gmhA:
undetectable		 2w8yB-5gmhA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 7 ILE A  80
PHE A 123
ARG A  97
THR A  71
 None
 1.03A 2zxwN-5gmhA:
undetectable
2zxwW-5gmhA:
undetectable		 2zxwN-5gmhA:
20.57
2zxwW-5gmhA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 548
LEU A 547
PHE A 549
ILE A 508
LEU A 533
 NAG  A 902 (-3.9A)
None
None
None
None
 1.11A 3hj3A-5gmhA:
undetectable		 3hj3A-5gmhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 548
LEU A 547
PHE A 549
ILE A 508
LEU A 533
 NAG  A 902 (-3.9A)
None
None
None
None
 1.13A 3hj3B-5gmhA:
undetectable		 3hj3B-5gmhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 THR A  71
LYS A 212
GLU A  93
 None
None
NAG  A 905 (-3.5A)
 0.56A 3ijdB-5gmhA:
undetectable		 3ijdB-5gmhA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 11 ALA A 412
LEU A 390
ASN A 407
ILE A 377
PHE A 382
 None
 1.31A 3jw5A-5gmhA:
undetectable		 3jw5A-5gmhA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 404
PHE A 382
ILE A 409
ALA A 412
LEU A 414
 None
 1.24A 3n8xA-5gmhA:
undetectable		 3n8xA-5gmhA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 404
PHE A 382
ILE A 409
ALA A 412
LEU A 414
 None
 1.02A 3n8xB-5gmhA:
undetectable		 3n8xB-5gmhA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 ASP A 548
GLU A 625
SER A 429
 NAG  A 902 (-3.9A)
None
NAG  A 902 ( 4.2A)
 0.63A 3p2kA-5gmhA:
undetectable		 3p2kA-5gmhA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_A_TOYA305_1
(APH(2'')-ID)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 320
SER A 257
ASP A 255
ASP A 346
TYR A 464
 None
 1.29A 3sg8A-5gmhA:
undetectable		 3sg8A-5gmhA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_B_TOYB305_1
(APH(2'')-ID)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 320
SER A 257
ASP A 255
ASP A 346
TYR A 464
 None
 1.32A 3sg8B-5gmhA:
0.0		 3sg8B-5gmhA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 6 LEU A 232
PHE A 245
ALA A 285
LEU A 279
 None
 1.01A 3t3zA-5gmhA:
undetectable		 3t3zA-5gmhA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 5 LEU A 595
ILE A 573
ALA A 561
PHE A 562
 None
 1.08A 4dc3B-5gmhA:
undetectable		 4dc3B-5gmhA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_B_KANB402_1
(APH(2')-ID)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ASP A 320
SER A 257
ASP A 255
ASP A 346
TYR A 464
 None
 1.36A 4dfuB-5gmhA:
undetectable		 4dfuB-5gmhA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 129
LEU A 150
LEU A 171
ILE A  94
ARG A 473
 None
 1.00A 4f4dA-5gmhA:
undetectable		 4f4dA-5gmhA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 ARG A 422
LEU A 423
GLU A 400
 SO4  A 917 (-3.9A)
None
None
 0.74A 4l3gF-5gmhA:
undetectable		 4l3gF-5gmhA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 8 ARG A 296
LEU A 256
ASN A 300
ILE A 281
 None
 1.09A 4l7iA-5gmhA:
undetectable		 4l7iA-5gmhA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 171
LEU A 168
ILE A 142
ASN A 214
LEU A 153
 None
 1.02A 4lmnA-5gmhA:
undetectable		 4lmnA-5gmhA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 VAL A 381
GLY A 405
ASP A 403
PHE A 349
ASP A 346
 None
 1.37A 4pevB-5gmhA:
undetectable		 4pevB-5gmhA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ALA A 285
VAL A 216
LEU A 256
LEU A 223
LEU A 230
 None
 1.08A 4qzuC-5gmhA:
undetectable		 4qzuC-5gmhA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 9 LEU A 171
LEU A 179
ILE A 163
PRO A 220
LEU A 211
 None
 1.41A 5g48B-5gmhA:
undetectable		 5g48B-5gmhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 5 LEU A 665
LEU A 711
PHE A 670
LEU A 704
 None
 1.03A 5gtrA-5gmhA:
undetectable		 5gtrA-5gmhA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 ILE A  77
LEU A 132
ILE A  94
LEU A  91
LEU A 116
 None
 1.07A 5ienA-5gmhA:
undetectable		 5ienA-5gmhA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 547
LEU A 498
LEU A 524
ASN A 503
ILE A 508
 None
 1.12A 5itzB-5gmhA:
undetectable		 5itzB-5gmhA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 12 LEU A 533
LEU A 565
PHE A 538
ILE A 573
LEU A 621
 None
 1.05A 5ljcA-5gmhA:
undetectable		 5ljcA-5gmhA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 SER A 299
SER A 301
PHE A 268
 None
 0.89A 5mugA-5gmhA:
undetectable		 5mugA-5gmhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 7 ARG A 378
THR A 406
GLN A 323
GLY A 379
 None
 0.93A 5nzyA-5gmhA:
undetectable		 5nzyA-5gmhA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 8 ALA A 412
ILE A 505
ASP A 512
ILE A 508
 None
 0.96A 5t8sA-5gmhA:
undetectable		 5t8sA-5gmhA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 6 ILE A 608
MET A 616
THR A 615
LEU A 645
 None
 1.03A 5z86N-5gmhA:
undetectable
5z86W-5gmhA:
undetectable		 5z86N-5gmhA:
20.57
5z86W-5gmhA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		4 / 6 ILE A 608
MET A 616
THR A 615
LEU A 645
 None
 1.03A 5zcoN-5gmhA:
undetectable
5zcoW-5gmhA:
undetectable		 5zcoN-5gmhA:
20.57
5zcoW-5gmhA:
5.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 7 THR A 532
ASP A 555
LEU A 557
ILE A 585
THR A 586
 SO4  A 912 (-3.4A)
RX8  A 901 (-2.7A)
RX8  A 901 (-3.8A)
RX8  A 901 (-4.2A)
RX8  A 901 (-4.1A)
 0.25A 5zsfA-5gmhA:
21.1
5zsfB-5gmhA:
27.9		 5zsfA-5gmhA:
100.00
5zsfB-5gmhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		5 / 9 THR A 532
ASP A 555
LEU A 557
ILE A 585
THR A 586
 SO4  A 912 (-3.4A)
RX8  A 901 (-2.7A)
RX8  A 901 (-3.8A)
RX8  A 901 (-4.2A)
RX8  A 901 (-4.1A)
 0.20A 5zsfA-5gmhA:
61.2
5zsfB-5gmhA:
59.6		 5zsfA-5gmhA:
100.00
5zsfB-5gmhA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5gmh TOLL-LIKE RECEPTOR 7
(Macaca
mulatta) 		3 / 3 PHE A 420
ARG A 422
GLN A 419
 None
SO4  A 917 (-3.9A)
None
 1.13A 6g1pB-5gmhA:
undetectable		 6g1pB-5gmhA:
16.89