SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  72
GLY A 114
THR A 125
ASN A 193
ALA A  68
 None
 0.92A 1nv8A-5gndA:
undetectable		 1nv8A-5gndA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 ASP A 154
GLY A 238
SER A 113
VAL A  69
ALA A 127
 None
 1.19A 1nw5A-5gndA:
undetectable		 1nw5A-5gndA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.84A 1p7lD-5gndA:
undetectable		 1p7lD-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.84A 1p7lC-5gndA:
undetectable		 1p7lC-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.85A 1rg9B-5gndA:
undetectable		 1rg9B-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.86A 1rg9A-5gndA:
undetectable		 1rg9A-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.84A 1rg9D-5gndA:
undetectable		 1rg9D-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.84A 1rg9C-5gndA:
undetectable		 1rg9C-5gndA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLU A 247
ILE A 226
LEU A 209
ASN A 181
ILE A 249
 None
 0.95A 2e7fA-5gndA:
undetectable		 2e7fA-5gndA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLU A 247
ILE A 226
LEU A 209
ASN A 181
ILE A 249
 None
 0.95A 2e7fB-5gndA:
undetectable		 2e7fB-5gndA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.88A 2pxcA-5gndA:
undetectable		 2pxcA-5gndA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 232
GLY A 192
ALA A 190
VAL A 195
ASP A  73
 None
 1.08A 2yvlD-5gndA:
undetectable		 2yvlD-5gndA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		3 / 3 PRO A 330
GLU A 361
TYR A 288
 None
 0.63A 2zmbA-5gndA:
undetectable		 2zmbA-5gndA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 7 ILE A 117
LEU A 124
PHE A 115
THR A 178
 None
 1.03A 3ag2N-5gndA:
undetectable
3ag2W-5gndA:
undetectable		 3ag2N-5gndA:
20.16
3ag2W-5gndA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 7 ILE A 117
LEU A 124
PHE A 115
THR A 178
 None
 1.04A 3ag4N-5gndA:
undetectable
3ag4W-5gndA:
undetectable		 3ag4N-5gndA:
20.16
3ag4W-5gndA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 9 PHE A 115
VAL A  69
GLY A  66
ILE A 189
GLY A 192
 None
 1.06A 3csjB-5gndA:
undetectable		 3csjB-5gndA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		3 / 3 VAL A 138
LYS A 136
HIS A 128
 None
 0.75A 3elzA-5gndA:
undetectable		 3elzA-5gndA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A 115
VAL A  69
ILE A 189
GLY A 192
 None
 0.97A 3gssA-5gndA:
undetectable		 3gssA-5gndA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A 115
VAL A  69
ILE A 189
GLY A 192
 None
 0.97A 3gssB-5gndA:
undetectable		 3gssB-5gndA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 10 PHE A 115
VAL A  69
GLY A  66
ILE A 189
GLY A 192
 None
 1.06A 3km6A-5gndA:
undetectable		 3km6A-5gndA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 11 THR A 228
ALA A 231
ALA A 188
GLY A 204
SER A 207
 None
 0.93A 3mg0K-5gndA:
undetectable
3mg0L-5gndA:
undetectable		 3mg0K-5gndA:
18.96
3mg0L-5gndA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 371
LEU A 382
ALA A 334
ARG A 375
GLY A 290
 None
 1.08A 3olsA-5gndA:
undetectable		 3olsA-5gndA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.83A 3p97A-5gndA:
undetectable		 3p97A-5gndA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 238
SER A 237
ASP A 131
THR A 153
 None
 0.82A 3pwwA-5gndA:
undetectable		 3pwwA-5gndA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.84A 4ctjA-5gndA:
undetectable		 4ctjA-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.83A 4ctkA-5gndA:
undetectable		 4ctkA-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 ASN A 193
ARG A 141
LEU A 140
ILE A 164
 None
 1.07A 4l7iA-5gndA:
undetectable		 4l7iA-5gndA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 9 ALA A 265
ILE A 249
VAL A 248
ALA A 271
ILE A 268
 None
 1.06A 4lbgB-5gndA:
undetectable		 4lbgB-5gndA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.71A 4ndnB-5gndA:
undetectable		 4ndnB-5gndA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 247
ILE A 249
ASP A 186
ILE A 206
 None
 0.89A 4ndnD-5gndA:
undetectable		 4ndnD-5gndA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 361
THR A 157
HIS A 286
 None
 0.64A 4q15A-5gndA:
undetectable		 4q15A-5gndA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 361
THR A 157
HIS A 286
 None
 0.67A 4q15B-5gndA:
undetectable		 4q15B-5gndA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A 200
THR A 202
ALA A 190
ALA A 230
ASN A 252
 None
 1.44A 4u15A-5gndA:
undetectable		 4u15A-5gndA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 11 GLY A 114
ALA A 271
ILE A 268
LEU A 176
ILE A 116
 None
 1.14A 4xumB-5gndA:
undetectable		 4xumB-5gndA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 361
THR A 157
HIS A 286
 None
 0.64A 4ydqB-5gndA:
undetectable		 4ydqB-5gndA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.82A 5e9qA-5gndA:
undetectable		 5e9qA-5gndA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.77A 5ec8A-5gndA:
undetectable		 5ec8A-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.80A 5ehgA-5gndA:
undetectable		 5ehgA-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.94A 5ehgC-5gndA:
undetectable		 5ehgC-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.85A 5eifA-5gndA:
undetectable		 5eifA-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.80A 5eiwA-5gndA:
undetectable		 5eiwA-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.86A 5ekxB-5gndA:
undetectable		 5ekxB-5gndA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.90A 5ikmA-5gndA:
undetectable		 5ikmA-5gndA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.90A 5kqrA-5gndA:
undetectable		 5kqrA-5gndA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.87A 5kqsA-5gndA:
undetectable		 5kqsA-5gndA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.90A 5njvA-5gndA:
undetectable		 5njvA-5gndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.88A 5njvB-5gndA:
undetectable		 5njvB-5gndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.87A 5njvC-5gndA:
undetectable		 5njvC-5gndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 1.00A 5njvD-5gndA:
undetectable		 5njvD-5gndA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.87A 5vimA-5gndA:
undetectable		 5vimA-5gndA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.85A 5vimB-5gndA:
undetectable		 5vimB-5gndA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.92A 5wz1B-5gndA:
undetectable		 5wz1B-5gndA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.84A 5wz2A-5gndA:
undetectable		 5wz2A-5gndA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.82A 5wz2B-5gndA:
undetectable		 5wz2B-5gndA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 250
GLY A 114
GLY A 238
VAL A 138
ILE A 123
 None
 0.84A 5wz2C-5gndA:
undetectable		 5wz2C-5gndA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5gnd PUTATIVE SERINE
PROTEASE HHOA
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU A 356
VAL A 384
LEU A 371
LEU A 373
 None
 0.69A 6g9bA-5gndA:
undetectable
6g9bB-5gndA:
undetectable		 6g9bA-5gndA:
14.51
6g9bB-5gndA:
14.12