SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gnx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A  97
VAL A  90
TRP A  87
 None
 0.94A 1c4dC-5gnxA:
undetectable
1c4dD-5gnxA:
undetectable		 1c4dC-5gnxA:
4.25
1c4dD-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 THR A 356
THR A 290
HIS A 206
LEU A 225
 None
 1.37A 1d4fC-5gnxA:
undetectable		 1d4fC-5gnxA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 GLY A 450
GLY A  14
PHE A  15
ARG A  10
 None
 0.76A 1jhaA-5gnxA:
undetectable		 1jhaA-5gnxA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.96A 1jo4A-5gnxA:
undetectable		 1jo4A-5gnxA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.96A 1jo4B-5gnxA:
undetectable		 1jo4B-5gnxA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 SER A  88
ALA A 131
ASP A  41
GLU A  37
 None
 1.43A 1lqtA-5gnxA:
undetectable
1lqtB-5gnxA:
undetectable		 1lqtA-5gnxA:
24.00
1lqtB-5gnxA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 SER A  88
ALA A 131
ASP A  41
GLU A  37
 None
 1.43A 1lquA-5gnxA:
undetectable
1lquB-5gnxA:
undetectable		 1lquA-5gnxA:
24.00
1lquB-5gnxA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.92A 1magA-5gnxA:
undetectable		 1magA-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.92A 1magB-5gnxA:
undetectable		 1magB-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.90A 1nrmA-5gnxA:
undetectable		 1nrmA-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.90A 1nrmB-5gnxA:
undetectable		 1nrmB-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.94A 1nruA-5gnxA:
undetectable		 1nruA-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ALA A 198
VAL A 196
TRP A 253
 None
 0.94A 1nruB-5gnxA:
undetectable		 1nruB-5gnxA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 6 ASP A  57
ASP A  61
ASN A  64
GLU A  37
 None
 1.16A 1rjdC-5gnxA:
undetectable		 1rjdC-5gnxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 7 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.19A 1v55C-5gnxA:
undetectable
1v55N-5gnxA:
undetectable
1v55P-5gnxA:
undetectable		 1v55C-5gnxA:
18.70
1v55N-5gnxA:
20.29
1v55P-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 PHE A  15
GLY A  14
LEU A 121
MET A 354
TYR A 442
 None
 1.12A 1zgyA-5gnxA:
undetectable		 1zgyA-5gnxA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 LEU A 129
PRO A 130
LEU A 133
ILE A 144
 None
 0.80A 2qd4A-5gnxA:
undetectable		 2qd4A-5gnxA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.22A 2y69C-5gnxA:
undetectable
2y69N-5gnxA:
undetectable
2y69P-5gnxA:
undetectable		 2y69C-5gnxA:
18.70
2y69N-5gnxA:
20.29
2y69P-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.22A 3asnC-5gnxA:
undetectable
3asnN-5gnxA:
undetectable
3asnP-5gnxA:
undetectable		 3asnC-5gnxA:
18.70
3asnN-5gnxA:
20.29
3asnP-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 ARG A  82
TYR A 298
VAL A 174
ASN A 170
HIS A 126
 None
BGC  A 502 (-4.4A)
None
BGC  A 502 (-3.3A)
BGC  A 502 (-4.0A)
 1.48A 3bjmB-5gnxA:
undetectable		 3bjmB-5gnxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 LEU A 129
ASP A 134
ILE A  39
GLY A 138
 None
 0.85A 3bufA-5gnxA:
undetectable		 3bufA-5gnxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 TYR A  63
ASP A  61
ASP A  57
 None
 0.95A 3ou7B-5gnxA:
undetectable		 3ou7B-5gnxA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 10 ASP A 128
ILE A  39
GLY A 138
VAL A 176
ILE A 175
 None
 1.05A 3oxvB-5gnxA:
undetectable		 3oxvB-5gnxA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 ILE A  26
TRP A 413
TRP A 127
THR A 168
 None
BGC  A 502 (-4.1A)
None
None
 1.20A 3topA-5gnxA:
3.1		 3topA-5gnxA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 ARG A  82
TYR A 298
VAL A 174
ASN A 170
HIS A 126
 None
BGC  A 502 (-4.4A)
None
BGC  A 502 (-3.3A)
BGC  A 502 (-4.0A)
 1.48A 3w2tB-5gnxA:
undetectable		 3w2tB-5gnxA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.19A 3x2qC-5gnxA:
undetectable
3x2qN-5gnxA:
undetectable
3x2qP-5gnxA:
undetectable		 3x2qC-5gnxA:
18.70
3x2qN-5gnxA:
20.29
3x2qP-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 10 ILE A  39
GLY A 179
TYR A 180
GLU A 194
GLY A 183
 None
 1.24A 4bwlC-5gnxA:
10.9		 4bwlC-5gnxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 7 GLY A  28
ASP A  57
GLY A  56
HIS A  45
 None
 0.82A 4c5nA-5gnxA:
2.9		 4c5nA-5gnxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 GLY A  28
ASP A  57
GLY A  56
HIS A  45
 None
 0.79A 4c5nC-5gnxA:
2.7		 4c5nC-5gnxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 4 LEU A 129
PRO A 130
LEU A 133
ILE A 144
 None
 0.87A 4f4dB-5gnxA:
undetectable		 4f4dB-5gnxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 7 ASP A  61
GLN A 431
ASN A  64
TRP A  66
 None
 1.00A 4ii8A-5gnxA:
undetectable		 4ii8A-5gnxA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 ASP A  41
ALA A  35
SER A  38
ASP A 128
 None
 1.02A 4k0bB-5gnxA:
undetectable		 4k0bB-5gnxA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 ASP A  41
ALA A  35
SER A  38
ASP A 128
 None
 1.06A 4l7iB-5gnxA:
undetectable		 4l7iB-5gnxA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		3 / 3 ASP A 128
TRP A 405
SER A  84
 None
BGC  A 502 (-3.7A)
None
 1.07A 4lrhB-5gnxA:
undetectable		 4lrhB-5gnxA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 GLY A 439
ASP A 437
ILE A 446
GLY A  18
ARG A  75
 None
 1.29A 4obwC-5gnxA:
undetectable		 4obwC-5gnxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 11 PHE A 428
GLN A 431
ALA A 429
ILE A  26
ASP A  69
 None
 1.25A 4uuuA-5gnxA:
undetectable
4uuuB-5gnxA:
undetectable		 4uuuA-5gnxA:
15.14
4uuuB-5gnxA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 ASP A 177
TYR A 180
HIS A 206
LEU A 185
 None
 1.18A 5b1bA-5gnxA:
undetectable
5b1bC-5gnxA:
undetectable
5b1bP-5gnxA:
undetectable		 5b1bA-5gnxA:
20.29
5b1bC-5gnxA:
18.70
5b1bP-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 4 TYR A 402
GLY A 439
SER A 438
LEU A 382
 None
 1.43A 5bphC-5gnxA:
undetectable		 5bphC-5gnxA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 GLY A 222
TRP A 166
LEU A 258
GLY A 207
GLY A 217
 None
 1.07A 5d4uA-5gnxA:
undetectable		 5d4uA-5gnxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 GLY A 222
TRP A 166
LEU A 258
GLY A 207
GLY A 217
 None
 1.07A 5d4uB-5gnxA:
undetectable		 5d4uB-5gnxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 GLY A 222
TRP A 166
LEU A 258
GLY A 207
GLY A 217
 None
 1.00A 5d4uC-5gnxA:
undetectable		 5d4uC-5gnxA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 PHE A  15
GLY A  14
LEU A 121
MET A 354
TYR A 442
 None
 1.21A 5ji0D-5gnxA:
undetectable		 5ji0D-5gnxA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 9 SER A  38
ASP A  57
TYR A 417
LEU A 411
SER A  86
 None
 1.48A 5l1fB-5gnxA:
0.0		 5l1fB-5gnxA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_C_K1SC305_0
(ADP-SUGAR
PYROPHOSPHATASE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 TRP A 342
GLU A 345
VAL A 341
LEU A 295
 None
 1.41A 5qjqC-5gnxA:
0.0
5qjqD-5gnxA:
0.0		 5qjqC-5gnxA:
18.51
5qjqD-5gnxA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 8 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.19A 5xdxC-5gnxA:
undetectable
5xdxN-5gnxA:
undetectable
5xdxP-5gnxA:
undetectable		 5xdxC-5gnxA:
18.99
5xdxN-5gnxA:
20.29
5xdxP-5gnxA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 7 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.24A 5z84C-5gnxA:
undetectable
5z84N-5gnxA:
undetectable
5z84P-5gnxA:
undetectable		 5z84C-5gnxA:
18.70
5z84N-5gnxA:
20.29
5z84P-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 7 LEU A 185
ASP A 177
TYR A 180
HIS A 206
 None
 1.26A 5z85C-5gnxA:
undetectable
5z85N-5gnxA:
undetectable
5z85P-5gnxA:
undetectable		 5z85C-5gnxA:
18.70
5z85N-5gnxA:
20.29
5z85P-5gnxA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 THR A 356
THR A 290
HIS A 206
LEU A 225
 None
 1.36A 6aphA-5gnxA:
undetectable		 6aphA-5gnxA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 ARG A  82
TYR A 298
VAL A 174
ASN A 170
HIS A 126
 None
BGC  A 502 (-4.4A)
None
BGC  A 502 (-3.3A)
BGC  A 502 (-4.0A)
 1.49A 6b1eB-5gnxA:
undetectable		 6b1eB-5gnxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		4 / 5 THR A 356
THR A 290
HIS A 206
LEU A 225
 None
 1.36A 6gbnB-5gnxA:
undetectable		 6gbnB-5gnxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5gnx BETA-GLUCOSIDASE
(metagenome) 		5 / 12 PHE A  15
GLY A  14
LEU A 121
MET A 354
TYR A 442
 None
 1.16A 6md4A-5gnxA:
undetectable		 6md4A-5gnxA:
11.27