SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5go6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5go6 PUTATIVE SECRETED
PROTEIN
(Streptomyces
avermitilis) 		5 / 12 LEU A 109
PHE A 137
ALA A 125
GLY A 119
LEU A 118
 None
 1.10A 1fe2A-5go6A:
undetectable		 1fe2A-5go6A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5go6 PUTATIVE SECRETED
PROTEIN
(Streptomyces
avermitilis) 		4 / 5 ILE A 162
LEU A 143
ALA A 212
PHE A 137
 None
 1.04A 2opxA-5go6A:
undetectable		 2opxA-5go6A:
18.86