SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		4 / 7 MET A  77
ILE A  71
ARG A  92
GLY A  55
 None
 1.24A 2pnjB-5golA:
undetectable		 2pnjB-5golA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		3 / 3 TYR A 121
GLU A 109
ASP A  24
 None
 0.73A 3bxoA-5golA:
undetectable		 3bxoA-5golA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		3 / 3 TYR A 121
GLU A 109
ASP A  24
 None
 0.72A 3bxoB-5golA:
undetectable		 3bxoB-5golA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		5 / 12 GLU A 109
THR A 110
ILE A 111
GLY A 112
ILE A 118
 None
 1.20A 5ifuA-5golA:
undetectable		 5ifuA-5golA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		5 / 10 GLY A  17
ASN A  16
ALA A 129
PRO A 128
GLY A  69
 None
 1.07A 6e5zA-5golA:
undetectable		 6e5zA-5golA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 5gol CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA
(Moorella
thermoacetica) 		5 / 10 GLY A  17
ASN A  16
ALA A 129
PRO A 128
GLY A  70
 None
 1.12A 6e5zA-5golA:
undetectable		 6e5zA-5golA:
20.11