SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5goo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
GLU A 414
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
GOL  A 502 ( 4.9A)
 0.61A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
GLU A 414
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
GOL  A 502 ( 4.9A)
 1.05A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.09A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
GLU A 414
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
GOL  A 502 ( 4.9A)
 0.61A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
GLU A 414
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
GOL  A 502 ( 4.9A)
 1.05A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.09A 1agmA-5gooA:
22.1		 1agmA-5gooA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 ALA A 437
VAL A 378
TRP A 381
 None
 0.90A 1bdwA-5gooA:
undetectable
1bdwB-5gooA:
undetectable		 1bdwA-5gooA:
2.98
1bdwB-5gooA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 5 ALA A 100
ALA A 121
LYS A 120
GLU A 119
 None
FRU  A 501 (-3.3A)
None
None
 0.82A 1e7cA-5gooA:
undetectable		 1e7cA-5gooA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 TYR A  47
ASP A  54
GLY A 183
TYR A 370
GLU A 414
 FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
None
FRU  A 501 (-4.8A)
GOL  A 502 ( 4.9A)
 1.29A 1gahA-5gooA:
22.1		 1gahA-5gooA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 439
GLY A 438
VAL A 343
ALA A 385
LEU A 388
 None
 1.16A 1gs4A-5gooA:
undetectable		 1gs4A-5gooA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		3 / 4 LYS A 392
ALA A 387
MET A 327
 None
 1.00A 1hk3A-5gooA:
undetectable		 1hk3A-5gooA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
ASN A 365
TYR A 370
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
None
FRU  A 501 (-4.8A)
 1.19A 1lf9A-5gooA:
24.8		 1lf9A-5gooA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		7 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
ASN A 365
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
None
FRU  A 501 (-4.8A)
None
 1.21A 1lf9B-5gooA:
9.6		 1lf9B-5gooA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 ALA A 207
LEU A 168
LEU A 232
LEU A 225
 None
 0.81A 1mt1D-5gooA:
undetectable
1mt1E-5gooA:
undetectable		 1mt1D-5gooA:
13.11
1mt1E-5gooA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 4 VAL A  56
ALA A  59
LEU A  75
PHE A  74
 None
 0.98A 1q97B-5gooA:
undetectable		 1q97B-5gooA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
ASN A 365
TYR A 370
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
None
FRU  A 501 (-4.8A)
 1.16A 1ulvA-5gooA:
28.9		 1ulvA-5gooA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.09A 1ulvA-5gooA:
28.9		 1ulvA-5gooA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 6 GLU A 195
ASP A 301
PHE A 305
ARG A 303
 None
 1.19A 2a3bB-5gooA:
undetectable		 2a3bB-5gooA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
TYR A 370
GLU A 414
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
GOL  A 502 ( 4.9A)
 1.18A 2f6dA-5gooA:
21.7		 2f6dA-5gooA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.14A 2f6dA-5gooA:
21.7		 2f6dA-5gooA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 11 LEU A 136
ILE A 200
PRO A 197
MET A 311
LEU A 232
 None
 1.28A 2ft9A-5gooA:
undetectable		 2ft9A-5gooA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 LEU A 164
LEU A  97
MET A  98
 None
 0.75A 2itzA-5gooA:
undetectable		 2itzA-5gooA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 9 LEU A 215
ILE A 135
ALA A 210
GLY A 230
LEU A 232
 None
 1.07A 2v0mB-5gooA:
undetectable		 2v0mB-5gooA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 4 GLN A 324
SER A 323
GLY A 391
LYS A 389
 None
 1.30A 3rumA-5gooA:
0.0		 3rumA-5gooA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A 325
ASP A 246
TRP A 244
 None
 0.86A 4xdqA-5gooA:
undetectable		 4xdqA-5gooA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 8 MET A 311
LEU A 314
GLU A 453
LEU A 136
 None
 1.26A 5dxeA-5gooA:
undetectable		 5dxeA-5gooA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 4 LEU A 423
TYR A 347
PRO A 367
ILE A 366
 None
 1.09A 5esgA-5gooA:
undetectable		 5esgA-5gooA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ILE A 160
ALA A 211
PHE A 204
LEU A 215
VAL A 228
 None
 1.33A 5hw4B-5gooA:
undetectable		 5hw4B-5gooA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 438
ALA A 396
SER A 456
ILE A 455
PHE A 454
 None
 1.01A 5igyA-5gooA:
undetectable		 5igyA-5gooA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 438
ALA A 396
SER A 456
ILE A 455
PHE A 454
 None
 0.97A 5ih0A-5gooA:
undetectable		 5ih0A-5gooA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 9 ILE A 313
ALA A 312
ILE A 455
ALA A 385
LEU A 382
 None
 1.14A 5mvmA-5gooA:
undetectable
5mvmE-5gooA:
undetectable		 5mvmA-5gooA:
13.37
5mvmE-5gooA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 8 MET A 311
LEU A 314
GLU A 453
LEU A 136
 None
 1.27A 6cbzA-5gooA:
undetectable		 6cbzA-5gooA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		4 / 5 GLU A 111
VAL A 104
LEU A 113
HIS A  84
 None
 1.29A 6dyoA-5gooA:
undetectable		 6dyoA-5gooA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
None
 0.90A 6fhwA-5gooA:
22.9		 6fhwA-5gooA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.06A 6fhwA-5gooA:
22.9		 6fhwA-5gooA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ARG A  53
ASP A  54
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-4.4A)
GOL  A 502 (-2.9A)
None
 0.90A 6fhwB-5gooA:
23.2		 6fhwB-5gooA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 5goo ALKALINE INVERTASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  36
TYR A  47
ASP A  54
TYR A 370
TRP A 376
 GOL  A 502 ( 4.2A)
FRU  A 501 (-4.3A)
GOL  A 502 (-2.9A)
FRU  A 501 (-4.8A)
None
 1.06A 6fhwB-5gooA:
23.2		 6fhwB-5gooA:
11.50