SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5got'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5got LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PHOSPHATASE FAMILY
PROTEIN
(Streptococcus
pyogenes) 		4 / 5 PHE A 108
PHE A   6
MET A  22
SER A  24
 None
 1.25A 1wrkB-5gotA:
undetectable		 1wrkB-5gotA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5got LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PHOSPHATASE FAMILY
PROTEIN
(Streptococcus
pyogenes) 		4 / 7 ASP A 121
GLY A  50
THR A  51
ILE A  54
 None
 0.86A 4acaC-5gotA:
4.3		 4acaC-5gotA:
14.32