SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 5gp0 NUDIX HYDROLASE 1
(Arabidopsis
thaliana) 		4 / 6 ILE E  22
LEU E  17
LEU E 122
ASP E 118
 None
 0.91A 2rlfA-5gp0E:
undetectable
2rlfD-5gp0E:
undetectable		 2rlfA-5gp0E:
14.19
2rlfD-5gp0E:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5gp0 NUDIX HYDROLASE 1
(Arabidopsis
thaliana) 		4 / 6 GLU E  60
PRO E 108
LYS E 110
GLU E 109
 None
None
GPP  E 202 ( 4.3A)
None
 1.37A 4a7tA-5gp0E:
undetectable		 4a7tA-5gp0E:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5gp0 NUDIX HYDROLASE 1
(Arabidopsis
thaliana) 		3 / 3 VAL E  12
GLU E 107
GLU E  59
 None
 0.93A 5jsdB-5gp0E:
undetectable
5jsdC-5gp0E:
undetectable		 5jsdB-5gp0E:
11.28
5jsdC-5gp0E:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5gp0 NUDIX HYDROLASE 1
(Arabidopsis
thaliana) 		5 / 12 ASN E 139
LEU E  23
PRO E  39
LEU E 130
PHE E  15
 None
None
None
GPP  E 202 ( 4.2A)
None
 1.14A 5xxiA-5gp0E:
undetectable		 5xxiA-5gp0E:
14.50