SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 5gp7 TANKYRASE-1
(Homo
sapiens) 		5 / 12 LEU A 921
GLY A 926
ALA A 927
ASP A 928
LEU A 922
 None
 0.90A 3ogqB-5gp7A:
undetectable		 3ogqB-5gp7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5gp7 TANKYRASE-1
(Homo
sapiens) 		4 / 4 LYS A 813
ASN A 876
ASP A 867
ASP A 809
 None
 1.32A 4o1eB-5gp7A:
undetectable		 4o1eB-5gp7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5gp7 TANKYRASE-1
(Homo
sapiens) 		3 / 3 ASP A 900
GLY A 869
ASP A 867
 None
 0.53A 4xdtA-5gp7A:
undetectable		 4xdtA-5gp7A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5gp7 TANKYRASE-1
(Homo
sapiens) 		3 / 3 LYS A 821
LEU A 822
ARG A 818
 None
 0.92A 5yw0A-5gp7A:
undetectable		 5yw0A-5gp7A:
18.89