SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5gp9 TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Bacillus
halodurans) 		5 / 9 PHE A  92
VAL A 184
LEU A 188
PHE A 144
LEU A 161
 None
 1.34A 1wrkA-5gp9A:
undetectable
1wrkB-5gp9A:
undetectable		 1wrkA-5gp9A:
22.03
1wrkB-5gp9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5gp9 TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Bacillus
halodurans) 		4 / 7 THR A 166
LEU A 124
LYS A 119
GLN A  60
 None
PLM  A 203 ( 4.7A)
None
None
 1.01A 4ib4A-5gp9A:
undetectable		 4ib4A-5gp9A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gp9 TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Bacillus
halodurans) 		5 / 12 LEU A 189
GLU A  81
ASP A  79
LEU A 134
GLY A 138
 None
None
None
GOL  A 202 (-4.6A)
None
 1.38A 4pgfA-5gp9A:
undetectable		 4pgfA-5gp9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5gp9 TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Bacillus
halodurans) 		5 / 12 ASP A  79
LEU A 130
GLY A 138
PHE A 144
LEU A 189
 None
 1.20A 4retA-5gp9A:
2.5		 4retA-5gp9A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5gp9 TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Bacillus
halodurans) 		5 / 12 ASP A  79
LEU A 130
GLY A 138
PHE A 144
LEU A 189
 None
 1.20A 4retC-5gp9A:
undetectable		 4retC-5gp9A:
11.19