SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gpl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 200
PHE A  49
ILE A  79
ASN A  78
LEU A  76
 None
 1.21A 1dhfB-5gplA:
undetectable		 1dhfB-5gplA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 200
PHE A  49
ILE A  79
ASN A  78
LEU A  76
 None
 1.16A 1dlsA-5gplA:
undetectable		 1dlsA-5gplA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE A 165
LEU A  96
LEU A 185
LEU A 181
 None
 0.98A 2bfpA-5gplA:
undetectable		 2bfpA-5gplA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 200
PHE A  49
ILE A  79
ASN A  78
LEU A  76
 None
 1.16A 2w3bB-5gplA:
undetectable		 2w3bB-5gplA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.39A 3dqtA-5gplA:
undetectable
3dqtB-5gplA:
undetectable		 3dqtA-5gplA:
19.11
3dqtB-5gplA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP A  69
TYR A 103
LEU A  73
ASN A 101
 None
 0.99A 3lm8A-5gplA:
undetectable
3lm8C-5gplA:
undetectable		 3lm8A-5gplA:
20.42
3lm8C-5gplA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 SER A  70
VAL A  51
PHE A 161
GLU A  55
 None
 1.45A 3n5tA-5gplA:
undetectable
3n5tB-5gplA:
undetectable		 3n5tA-5gplA:
19.03
3n5tB-5gplA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 148
LYS A 145
PRO A 146
 None
 0.91A 4dv1L-5gplA:
undetectable		 4dv1L-5gplA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.42A 4k5jA-5gplA:
undetectable
4k5jB-5gplA:
undetectable		 4k5jA-5gplA:
18.85
4k5jB-5gplA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 200
PHE A  49
ILE A  79
ASN A  78
LEU A  76
 None
 1.12A 4kebB-5gplA:
undetectable		 4kebB-5gplA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.42A 5adlA-5gplA:
undetectable
5adlB-5gplA:
undetectable		 5adlA-5gplA:
18.85
5adlB-5gplA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.41A 5fj3A-5gplA:
undetectable
5fj3B-5gplA:
undetectable		 5fj3A-5gplA:
18.85
5fj3B-5gplA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A  39
PRO A 191
TYR A  80
 None
 0.99A 5tzoB-5gplA:
undetectable		 5tzoB-5gplA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A  96
PHE A 161
ILE A  94
ALA A 186
ALA A 193
 None
 1.12A 5veuA-5gplA:
undetectable		 5veuA-5gplA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.40A 5vv7A-5gplA:
undetectable
5vv7B-5gplA:
undetectable		 5vv7A-5gplA:
18.85
5vv7B-5gplA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.42A 5vvnA-5gplA:
undetectable
5vvnB-5gplA:
undetectable		 5vvnA-5gplA:
18.85
5vvnB-5gplA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 SER A  70
VAL A  51
PHE A 161
GLU A  55
 None
 1.38A 6av6A-5gplA:
undetectable
6av6B-5gplA:
undetectable		 6av6A-5gplA:
12.77
6av6B-5gplA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
GLU A  55
SER A  70
VAL A  51
 None
 1.41A 6av6C-5gplA:
undetectable
6av6D-5gplA:
undetectable		 6av6C-5gplA:
12.77
6av6D-5gplA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 SER A  70
VAL A  51
PHE A 161
GLU A  55
 None
 1.37A 6av7A-5gplA:
undetectable
6av7B-5gplA:
undetectable		 6av7A-5gplA:
12.77
6av7B-5gplA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
ILE A  65
ILE A  79
ALA A 200
 None
 0.87A 6b5vA-5gplA:
undetectable
6b5vC-5gplA:
undetectable		 6b5vA-5gplA:
17.32
6b5vC-5gplA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 161
ILE A  65
ILE A  79
ALA A 200
 None
 0.88A 6b5vC-5gplA:
undetectable
6b5vD-5gplA:
undetectable		 6b5vC-5gplA:
17.32
6b5vD-5gplA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5gpl PUTATIVE NUCLEOSOME
ASSEMBLY PROTEIN
C36B7.08C
(Schizosaccharomy
ces
pombe) 		4 / 7 ALA A 200
PHE A 161
ILE A  65
ILE A  79
 None
 0.87A 6b5vB-5gplA:
undetectable
6b5vD-5gplA:
undetectable		 6b5vB-5gplA:
17.32
6b5vD-5gplA:
17.32