SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 501 (-3.7A)
 1.29A 1c4dA-5gpqA:
undetectable
1c4dB-5gpqA:
undetectable		 1c4dA-5gpqA:
5.21
1c4dB-5gpqA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 6 VAL A   9
VAL A  51
ILE A  61
ASN A 268
 None
 0.97A 1e06A-5gpqA:
undetectable		 1e06A-5gpqA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 8 SER A 256
THR A 226
ASN A 151
LEU A 248
 None
 1.02A 1lhvA-5gpqA:
undetectable		 1lhvA-5gpqA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 7 LYS A 278
GLU A 282
ALA A 277
ALA A  78
 None
 1.14A 1sn0B-5gpqA:
undetectable
1sn0D-5gpqA:
undetectable		 1sn0B-5gpqA:
14.69
1sn0D-5gpqA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 11 THR A  94
GLN A 326
ALA A 325
ALA A 304
ALA A 302
 None
 1.09A 2f16H-5gpqA:
undetectable
2f16I-5gpqA:
undetectable		 2f16H-5gpqA:
22.11
2f16I-5gpqA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 11 THR A  94
GLN A 326
ALA A 325
ALA A 304
ALA A 302
 None
 1.08A 2f16V-5gpqA:
undetectable
2f16W-5gpqA:
undetectable		 2f16V-5gpqA:
22.11
2f16W-5gpqA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 7 VAL A  98
ALA A 106
PHE A  93
PRO A  92
 None
 1.05A 2q6oA-5gpqA:
undetectable		 2q6oA-5gpqA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 6 PHE A 259
ALA A 163
LEU A 248
PRO A 160
 None
 0.96A 3bgdA-5gpqA:
undetectable		 3bgdA-5gpqA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 7 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.73A 3bjwC-5gpqA:
undetectable		 3bjwC-5gpqA:
12.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 501 (-4.4A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.7A)
MAL  A 501 (-3.9A)
MAL  A 501 ( 4.4A)
MAL  A 501 (-3.7A)
 0.17A 3jyrA-5gpqA:
62.4		 3jyrA-5gpqA:
78.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 7 ASN A  13
TRP A  63
TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 501 (-4.4A)
MAL  A 501 (-4.4A)
MAL  A 501 (-3.9A)
MAL  A 501 ( 4.4A)
MAL  A 501 (-3.7A)
None
 0.58A 3jyrA-5gpqA:
62.4		 3jyrA-5gpqA:
78.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 11 THR A  94
GLN A 326
ALA A 325
ALA A 304
ALA A 302
 None
 1.12A 3mg0V-5gpqA:
undetectable
3mg0W-5gpqA:
undetectable		 3mg0V-5gpqA:
22.11
3mg0W-5gpqA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 VAL A 197
LEU A 161
GLY A 188
ALA A 189
LEU A 362
 None
 0.98A 3n8yB-5gpqA:
undetectable		 3n8yB-5gpqA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.84A 3tbgB-5gpqA:
undetectable		 3tbgB-5gpqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 501 (-2.9A)
None
 0.83A 3tbgD-5gpqA:
undetectable		 3tbgD-5gpqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 GLY A 435
ALA A 434
ILE A 405
ILE A 378
VAL A 404
 None
 0.91A 3ucbA-5gpqA:
undetectable		 3ucbA-5gpqA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		5 / 12 ALA A 232
TYR A  18
TYR A 211
ASN A 235
GLY A 229
 None
 1.32A 3vwqA-5gpqA:
undetectable		 3vwqA-5gpqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 5 GLU A 309
ASP A 315
ASP A 288
ASN A 295
 None
 1.36A 3vywD-5gpqA:
undetectable		 3vywD-5gpqA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 7 SER A 353
ARG A 355
ILE A 349
ASP A 208
 None
 1.11A 4d33B-5gpqA:
undetectable		 4d33B-5gpqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 8 SER A 353
ARG A 355
ILE A 349
ASP A 208
 None
 0.98A 4d39A-5gpqA:
undetectable		 4d39A-5gpqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 7 SER A 353
ARG A 355
ILE A 349
ASP A 208
 None
 1.06A 4d39B-5gpqA:
undetectable		 4d39B-5gpqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 501 (-3.1A)
 0.99A 4n48A-5gpqA:
undetectable		 4n48A-5gpqA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 1.01A 5sxqB-5gpqA:
undetectable		 5sxqB-5gpqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		5 / 10 ALA A 445
LEU A 442
VAL A 441
LEU A 426
ILE A 405
 None
 1.08A 5v02B-5gpqA:
undetectable
5v02R-5gpqA:
undetectable		 5v02B-5gpqA:
11.56
5v02R-5gpqA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 12 ALA A 343
ALA A 339
GLY A 167
ALA A 189
PHE A 170
VAL A 182
 None
 1.44A 5w4zA-5gpqA:
undetectable		 5w4zA-5gpqA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		6 / 12 ALA A 343
ALA A 339
GLY A 167
ALA A 189
PHE A 170
VAL A 182
 None
 1.47A 5w4zB-5gpqA:
undetectable		 5w4zB-5gpqA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		3 / 3 TYR A 156
ASN A 228
LEU A 114
 MAL  A 501 (-3.9A)
None
None
 0.84A 6b58A-5gpqA:
undetectable		 6b58A-5gpqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Escherichia
coli;
Danio
rerio) 		5 / 11 PRO A 134
GLU A 131
PRO A 255
ALA A 164
PRO A 160
 None
 1.43A 6bm5A-5gpqA:
undetectable		 6bm5A-5gpqA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD
(Danio
rerio;
Escherichia
coli) 		4 / 7 ASP A 359
ALA A 363
LYS A 190
LEU A 193
 None
 1.08A 6ci6A-5gpqA:
undetectable		 6ci6A-5gpqA:
13.26