SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		8 / 9 TYR A 156
PHE A 184
GLY A 267
ASP A 306
MET A 381
TYR A 383
ASP A 384
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TRP  A 532 ( 0.5A)
 0.84A 1e9lA-5gprA:
42.6		 1e9lA-5gprA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 8 PHE A 379
GLY A 528
LEU A 549
PHE A 530
 PHE  A 379 ( 1.3A)
GLY  A 528 ( 0.0A)
LEU  A 549 ( 0.6A)
PHE  A 530 ( 1.3A)
 1.02A 1gsfC-5gprA:
undetectable		 1gsfC-5gprA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 GLU A 351
HIS A 377
HIS A 179
 GLU  A 351 ( 0.6A)
HIS  A 377 ( 1.0A)
HIS  A 179 ( 1.0A)
 0.70A 1oe2A-5gprA:
2.8		 1oe2A-5gprA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ILE A 541
GLY A 539
ASN A 176
ASN A 142
 ILE  A 541 ( 0.7A)
GLY  A 539 ( 0.0A)
ASN  A 176 ( 0.6A)
ASN  A 142 ( 0.6A)
 1.01A 1oniG-5gprA:
undetectable
1oniI-5gprA:
0.8		 1oniG-5gprA:
14.23
1oniI-5gprA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		10 / 11 TYR A 156
PHE A 184
GLY A 267
ASP A 306
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.39A 2a3aA-5gprA:
12.4		 2a3aA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A 156
PHE A 184
GLY A 267
TRP A 268
ASP A 306
GLU A 308
MET A 381
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TRP  A 532 ( 0.5A)
 0.65A 2a3aA-5gprA:
12.4		 2a3aA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		8 / 9 PHE A 184
GLY A 267
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.47A 2a3aB-5gprA:
43.1		 2a3aB-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A 156
PHE A 184
GLY A 267
TRP A 268
ASP A 306
GLU A 308
MET A 381
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.78A 2a3bA-5gprA:
43.0		 2a3bA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		10 / 11 TYR A 156
PHE A 184
GLY A 267
TRP A 268
ASP A 306
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
ASP  A 306 ( 0.5A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.57A 2a3bA-5gprA:
43.0		 2a3bA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		9 / 10 PHE A 184
GLY A 267
ASP A 306
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.67A 2a3bB-5gprA:
43.1		 2a3bB-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TYR A 156
TRP A 160
PHE A 184
GLY A 267
ASP A 306
GLU A 308
MET A 381
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
TRP  A 160 ( 0.5A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.72A 2a3cA-5gprA:
12.4		 2a3cA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		10 / 12 TYR A 156
TRP A 160
PHE A 184
GLY A 267
ASP A 306
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 TYR  A 156 ( 1.3A)
TRP  A 160 ( 0.5A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.44A 2a3cA-5gprA:
12.4		 2a3cA-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		11 / 12 TRP A 160
PHE A 184
GLY A 267
THR A 269
ASP A 306
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 TRP  A 160 ( 0.5A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
THR  A 269 ( 0.8A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.71A 2a3cB-5gprA:
43.1		 2a3cB-5gprA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 8 LYS A 243
GLY A 247
PHE A 299
ASP A 127
 LYS  A 243 ( 0.0A)
GLY  A 247 ( 0.0A)
PHE  A 299 ( 1.3A)
ASP  A 127 ( 0.5A)
 1.03A 2aouA-5gprA:
undetectable		 2aouA-5gprA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 5 PRO A 273
PRO A 186
ILE A 185
GLY A 266
 PRO  A 273 ( 1.1A)
PRO  A 186 ( 1.1A)
ILE  A 185 ( 0.7A)
GLY  A 266 ( 0.0A)
 1.08A 2jkjD-5gprA:
undetectable		 2jkjD-5gprA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 5 PRO A 273
PRO A 186
ILE A 185
GLY A 266
 PRO  A 273 ( 1.1A)
PRO  A 186 ( 1.1A)
ILE  A 185 ( 0.7A)
GLY  A 266 ( 0.0A)
 1.08A 2jkjF-5gprA:
undetectable		 2jkjF-5gprA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A 156
PHE A 184
GLY A 267
ASP A 306
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.93A 2uy4A-5gprA:
18.4		 2uy4A-5gprA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A 156
PHE A 184
GLY A 267
GLU A 308
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
GLU  A 308 ( 0.6A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.52A 2uy4A-5gprA:
18.4		 2uy4A-5gprA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1161_1
(ALLERGEN ARG R 1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 4 VAL A 521
TYR A 520
VAL A 417
SER A 382
 VAL  A 521 ( 0.6A)
TYR  A 520 ( 1.3A)
VAL  A 417 ( 0.6A)
SER  A 382 ( 0.0A)
 1.17A 2x45B-5gprA:
undetectable		 2x45B-5gprA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A 156
PHE A 184
GLY A 267
GLU A 308
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
GLU  A 308 ( 0.6A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.74A 2xtkA-5gprA:
19.8		 2xtkA-5gprA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A 156
PHE A 184
GLY A 267
ASP A 306
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.96A 2xtkB-5gprA:
19.7		 2xtkB-5gprA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A 156
PHE A 184
GLY A 267
GLU A 308
TYR A 383
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
GLU  A 308 ( 0.6A)
TYR  A 383 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.56A 2xtkB-5gprA:
19.7		 2xtkB-5gprA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_A_CTCA1385_0
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 10 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.21A 2y6rA-5gprA:
undetectable		 2y6rA-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A 217
PHE A 293
ILE A 193
ASP A 195
PHE A 204
 PHE  A 217 ( 1.3A)
PHE  A 293 ( 1.3A)
ILE  A 193 ( 0.4A)
ASP  A 195 ( 0.6A)
PHE  A 204 ( 1.3A)
 1.23A 2zznB-5gprA:
undetectable		 2zznB-5gprA:
20.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ARQ_A_DM5A606_1
(CHITINASE A)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 6 TRP A 268
LYS A 362
ASP A 384
TRP A 389
TYR A 411
ARG A 439
 TRP  A 268 ( 0.5A)
LYS  A 362 ( 0.0A)
ASP  A 384 ( 0.5A)
TRP  A 389 (-0.5A)
TYR  A 411 ( 1.3A)
ARG  A 439 ( 0.6A)
 0.55A 3arqA-5gprA:
55.3		 3arqA-5gprA:
50.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ARR_A_PNXA606_1
(CHITINASE A)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		7 / 7 TRP A 268
GLY A 359
LYS A 362
ASP A 384
TRP A 389
TYR A 411
ARG A 439
 TRP  A 268 ( 0.5A)
GLY  A 359 ( 0.0A)
LYS  A 362 ( 0.0A)
ASP  A 384 ( 0.5A)
TRP  A 389 (-0.5A)
TYR  A 411 ( 1.3A)
ARG  A 439 ( 0.6A)
 0.46A 3arrA-5gprA:
56.4		 3arrA-5gprA:
50.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ARR_A_PNXA607_1
(CHITINASE A)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		6 / 7 TRP A 160
SER A 203
HIS A 222
THR A 269
LEU A 270
TRP A 532
 TRP  A 160 ( 0.5A)
SER  A 203 ( 0.0A)
HIS  A 222 ( 1.0A)
THR  A 269 ( 0.8A)
LEU  A 270 ( 0.6A)
TRP  A 532 ( 0.5A)
 0.59A 3arrA-5gprA:
56.3		 3arrA-5gprA:
50.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ARU_A_PNXA606_1
(CHITINASE A)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		7 / 7 PHE A 309
GLY A 359
LYS A 362
ASP A 384
TRP A 389
TYR A 411
ARG A 439
 PHE  A 309 ( 1.3A)
GLY  A 359 ( 0.0A)
LYS  A 362 ( 0.0A)
ASP  A 384 ( 0.5A)
TRP  A 389 (-0.5A)
TYR  A 411 ( 1.3A)
ARG  A 439 ( 0.6A)
 0.46A 3aruA-5gprA:
56.0		 3aruA-5gprA:
50.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ARU_A_PNXA608_1
(CHITINASE A)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 6 TRP A 160
SER A 203
ALA A 206
HIS A 222
ASP A 223
 TRP  A 160 ( 0.5A)
SER  A 203 ( 0.0A)
ALA  A 206 ( 0.0A)
HIS  A 222 ( 1.0A)
ASP  A 223 ( 0.5A)
 0.57A 3aruA-5gprA:
56.0		 3aruA-5gprA:
50.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		11 / 11 TYR A 156
PHE A 184
GLY A 267
TRP A 268
ASP A 306
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
ASP  A 306 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.49A 3g6mA-5gprA:
7.2		 3g6mA-5gprA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 5 TRP A 268
MET A 381
ASP A 384
TRP A 389
 TRP  A 268 ( 0.5A)
MET  A 381 ( 0.0A)
ASP  A 384 ( 0.5A)
TRP  A 389 (-0.5A)
 0.75A 3g6mA-5gprA:
7.2		 3g6mA-5gprA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 290
SER A 354
ILE A 187
VAL A 366
TYR A 368
 VAL  A 290 ( 0.6A)
SER  A 354 ( 0.0A)
ILE  A 187 ( 0.7A)
VAL  A 366 ( 0.6A)
TYR  A 368 ( 1.3A)
 0.99A 3g8iA-5gprA:
undetectable		 3g8iA-5gprA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 4 GLY A 539
GLU A 140
ASP A 535
ASP A 540
 GLY  A 539 ( 0.0A)
GLU  A 140 ( 0.6A)
ASP  A 535 ( 0.6A)
ASP  A 540 ( 0.5A)
 1.26A 3mb5A-5gprA:
undetectable		 3mb5A-5gprA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 4 VAL A 152
PHE A 379
PHE A 380
VAL A 417
 VAL  A 152 ( 0.6A)
PHE  A 379 ( 1.3A)
PHE  A 380 ( 1.3A)
VAL  A 417 ( 0.6A)
 1.27A 3rv5C-5gprA:
undetectable
3rv5D-5gprA:
undetectable		 3rv5C-5gprA:
9.96
3rv5D-5gprA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ILE A 185
PHE A 299
MET A 250
GLY A 247
 ILE  A 185 ( 0.7A)
PHE  A 299 ( 1.3A)
MET  A 250 ( 0.0A)
GLY  A 247 ( 0.0A)
 1.13A 3sj0X-5gprA:
undetectable		 3sj0X-5gprA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.11A 3v3oB-5gprA:
undetectable		 3v3oB-5gprA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_D_T1CD401_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 10 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.18A 3v3oD-5gprA:
undetectable		 3v3oD-5gprA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		7 / 11 PHE A 184
GLY A 267
ASP A 306
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.80A 3wqvA-5gprA:
43.0		 3wqvA-5gprA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A 184
GLY A 267
TRP A 268
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
ARG A 439
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
ARG  A 439 ( 0.6A)
TRP  A 532 ( 0.5A)
 0.44A 3wqvA-5gprA:
43.0		 3wqvA-5gprA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		7 / 11 PHE A 184
GLY A 267
ASP A 306
TYR A 383
ASP A 384
TYR A 437
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
TRP  A 532 ( 0.5A)
 0.82A 3wqwA-5gprA:
43.0		 3wqwA-5gprA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A 184
GLY A 267
TRP A 268
GLU A 308
MET A 381
TYR A 383
ASP A 384
TYR A 437
ARG A 439
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
GLU  A 308 ( 0.6A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TYR  A 437 ( 1.3A)
ARG  A 439 ( 0.6A)
TRP  A 532 ( 0.5A)
 0.47A 3wqwA-5gprA:
43.0		 3wqwA-5gprA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.13A 4a6nA-5gprA:
undetectable		 4a6nA-5gprA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.13A 4a6nB-5gprA:
undetectable		 4a6nB-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.13A 4a6nC-5gprA:
undetectable		 4a6nC-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 10 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.22A 4a99A-5gprA:
undetectable		 4a99A-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.19A 4a99B-5gprA:
undetectable		 4a99B-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.21A 4a99C-5gprA:
undetectable		 4a99C-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A 309
ASN A 316
GLY A 312
GLY A 266
MET A 381
 PHE  A 309 ( 1.3A)
ASN  A 316 ( 0.6A)
GLY  A 312 ( 0.0A)
GLY  A 266 ( 0.0A)
MET  A 381 ( 0.0A)
 1.21A 4a99D-5gprA:
undetectable		 4a99D-5gprA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 6 GLN A 466
ARG A 165
ASP A 384
GLN A 397
 GLN  A 466 ( 0.6A)
ARG  A 165 ( 0.6A)
ASP  A 384 ( 0.5A)
GLN  A 397 ( 0.6A)
 1.31A 4azvA-5gprA:
undetectable		 4azvA-5gprA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 6 PHE A 286
ILE A 185
PRO A 186
PHE A 274
 PHE  A 286 ( 1.3A)
ILE  A 185 ( 0.7A)
PRO  A 186 ( 1.1A)
PHE  A 274 ( 1.3A)
 1.11A 4fgkA-5gprA:
undetectable		 4fgkA-5gprA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ASP A 361
TRP A 268
SER A 357
 ASP  A 361 ( 0.5A)
TRP  A 268 ( 0.5A)
SER  A 357 ( 0.0A)
 0.78A 4lrhB-5gprA:
undetectable		 4lrhB-5gprA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ASP A 361
TRP A 268
SER A 357
 ASP  A 361 ( 0.5A)
TRP  A 268 ( 0.5A)
SER  A 357 ( 0.0A)
 0.77A 4lrhF-5gprA:
undetectable		 4lrhF-5gprA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ILE A 506
ARG A 499
VAL A 497
GLU A 478
 ILE  A 506 ( 0.7A)
ARG  A 499 ( 0.6A)
VAL  A 497 ( 0.6A)
GLU  A 478 ( 0.6A)
 0.93A 4zzbC-5gprA:
undetectable
4zzbD-5gprA:
undetectable		 4zzbC-5gprA:
20.43
4zzbD-5gprA:
20.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GQB_A_GCSA602_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 268
GLU A 308
ASP A 384
 TRP  A 268 ( 0.5A)
GLU  A 308 ( 0.6A)
ASP  A 384 ( 0.5A)
 0.28A 5gqbA-5gprA:
67.9		 5gqbA-5gprA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GQB_A_GCSA603_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		8 / 8 PHE A 184
GLY A 267
TRP A 268
GLU A 308
TYR A 383
ASP A 384
ARG A 439
TRP A 532
 PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
TRP  A 268 ( 0.5A)
GLU  A 308 ( 0.6A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
ARG  A 439 ( 0.6A)
TRP  A 532 ( 0.5A)
 0.27A 5gqbA-5gprA:
67.9		 5gqbA-5gprA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GQB_A_GCSA604_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 4 TRP A 160
TRP A 268
THR A 269
LEU A 270
 TRP  A 160 ( 0.5A)
TRP  A 268 ( 0.5A)
THR  A 269 ( 0.8A)
LEU  A 270 ( 0.6A)
 0.16A 5gqbA-5gprA:
67.9		 5gqbA-5gprA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GQB_A_GCSA605_1
(CHITINASE)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 160
ILE A 200
SER A 203
 TRP  A 160 ( 0.5A)
ILE  A 200 ( 0.7A)
SER  A 203 ( 0.0A)
 0.27A 5gqbA-5gprA:
67.9		 5gqbA-5gprA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 6 VAL A 172
LEU A 177
LEU A 259
LEU A 181
 VAL  A 172 ( 0.6A)
LEU  A 177 ( 0.6A)
LEU  A 259 ( 0.6A)
LEU  A 181 ( 0.5A)
 0.82A 6f6sA-5gprA:
undetectable
6f6sB-5gprA:
undetectable		 6f6sA-5gprA:
11.09
6f6sB-5gprA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ARG A 165
PHE A 167
GLY A 161
 ARG  A 165 ( 0.6A)
PHE  A 167 ( 1.3A)
GLY  A 161 ( 0.0A)
 0.73A 6fgdA-5gprA:
undetectable		 6fgdA-5gprA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 438
GLY A 468
ASP A 509
ASP A 540
VAL A 461
 GLY  A 438 ( 0.0A)
GLY  A 468 ( 0.0A)
ASP  A 509 ( 0.6A)
ASP  A 540 ( 0.5A)
VAL  A 461 ( 0.6A)
 1.09A 6mhtA-5gprA:
undetectable		 6mhtA-5gprA:
20.46