SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 6 ARG A 317
ASP A 294
ASP A 247
GLU A 313
 None
 1.25A 1rjdA-5gq1A:
undetectable		 1rjdA-5gq1A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 6 ARG A 317
ASP A 294
ASP A 247
GLU A 313
 None
 1.24A 1rjdB-5gq1A:
undetectable		 1rjdB-5gq1A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 6 ARG A 317
ASP A 294
ASP A 247
GLU A 313
 None
 1.25A 1rjdC-5gq1A:
undetectable		 1rjdC-5gq1A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 8 SER A 308
ARG A 312
ASN A 277
ASP A 304
 None
 1.15A 1rs6A-5gq1A:
undetectable		 1rs6A-5gq1A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 LYS A 268
TYR A 254
PRO A 283
 None
 1.43A 2j9cC-5gq1A:
undetectable		 2j9cC-5gq1A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 5 ILE A 146
LEU A 310
ASP A 304
ALA A 145
 None
 1.01A 2opxA-5gq1A:
undetectable		 2opxA-5gq1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.83A 5ewzB-5gq1A:
undetectable		 5ewzB-5gq1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.87A 5m35B-5gq1A:
undetectable		 5m35B-5gq1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.86A 5m36A-5gq1A:
undetectable		 5m36A-5gq1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.89A 6fn9A-5gq1A:
undetectable		 6fn9A-5gq1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.86A 6fnaB-5gq1A:
undetectable		 6fnaB-5gq1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5gq1 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 MET A 193
GLN A 192
ARG A 241
 None
 0.89A 6fnbA-5gq1A:
undetectable		 6fnbA-5gq1A:
22.40