SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 9 ALA A 342
ASP A 341
GLY A 250
ILE A 234
ILE A 343
 None
NAG  A 704 ( 4.2A)
None
None
None
 1.13A 1hpvB-5gqfA:
undetectable		 1hpvB-5gqfA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 SER A 325
ASP A 349
PRO A 386
ASP A 416
ILE A 353
 None
None
None
NAG  A 704 (-4.4A)
None
 1.30A 1s14A-5gqfA:
undetectable		 1s14A-5gqfA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 SER A 325
ASP A 349
PRO A 386
ASP A 416
ILE A 353
 None
None
None
NAG  A 704 (-4.4A)
None
 1.36A 1s14B-5gqfA:
undetectable		 1s14B-5gqfA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 5 PHE A 498
LEU A 465
PHE A 503
SER A 485
 None
 1.32A 1wrkB-5gqfA:
undetectable		 1wrkB-5gqfA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A 249
GLY A 294
GLY A 340
ASP A 291
VAL A 237
 None
 0.95A 2oxtC-5gqfA:
undetectable		 2oxtC-5gqfA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 462
VAL A 481
SER A 455
PHE A 503
ASN A 501
 None
 1.24A 2y03A-5gqfA:
undetectable		 2y03A-5gqfA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 SER A 567
GLY A 358
ASN A 401
ASP A 458
TYR A 429
 None
 1.26A 3a27A-5gqfA:
undetectable		 3a27A-5gqfA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 SER A 567
GLY A 358
TYR A 334
ASN A 401
ASP A 458
 None
 1.19A 3a27A-5gqfA:
undetectable		 3a27A-5gqfA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 380
GLY A 339
ILE A 186
HIS A 364
TRP A 189
 NAG  A 704 (-3.6A)
None
None
None
None
 1.34A 3bwyA-5gqfA:
undetectable		 3bwyA-5gqfA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 9 ALA A 342
ASP A 341
GLY A 250
ILE A 234
ILE A 343
 None
NAG  A 704 ( 4.2A)
None
None
None
 1.08A 3ekvB-5gqfA:
undetectable		 3ekvB-5gqfA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A 337
GLY A 339
LEU A 403
ASN A 401
ILE A 186
 None
 0.84A 3embA-5gqfA:
undetectable		 3embA-5gqfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 ALA A 547
LEU A 554
ILE A 502
LEU A 621
ASP A 620
 None
 1.00A 3gcsA-5gqfA:
undetectable		 3gcsA-5gqfA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 7 ILE A 241
TYR A 370
THR A 371
GLY A 378
 None
 0.89A 3gssA-5gqfA:
undetectable		 3gssA-5gqfA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 4 LEU A 345
MET A 224
ILE A 234
ASP A 230
 None
 1.26A 3hecA-5gqfA:
undetectable		 3hecA-5gqfA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 10 TYR A 531
ASP A 541
PHE A 503
VAL A 487
TRP A 515
 None
 1.35A 3ihzA-5gqfA:
undetectable		 3ihzA-5gqfA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 ASN A 402
ASP A 341
ARG A 204
 None
NAG  A 704 ( 4.2A)
None
 0.91A 3k13C-5gqfA:
undetectable		 3k13C-5gqfA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 438
SER A 496
VAL A 487
ASN A 477
PHE A 503
 None
 1.46A 3nhxA-5gqfA:
undetectable		 3nhxA-5gqfA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 11 TYR A 531
ASP A 541
PHE A 503
VAL A 487
TRP A 515
 None
 1.39A 3o5rA-5gqfA:
undetectable		 3o5rA-5gqfA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 TYR A 370
ASP A 291
ASP A 179
 None
 0.94A 3ou6B-5gqfA:
undetectable		 3ou6B-5gqfA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 TYR A 183
ASP A 236
ASP A 291
 None
 0.90A 3ou7B-5gqfA:
undetectable		 3ou7B-5gqfA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 11 TYR A 431
ASN A 457
GLY A 558
ALA A 557
VAL A 532
 None
 1.15A 3rukD-5gqfA:
undetectable		 3rukD-5gqfA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		6 / 9 ALA A 342
ASP A 341
GLY A 250
ILE A 234
ILE A 330
ILE A 343
 None
NAG  A 704 ( 4.2A)
None
None
None
None
 1.29A 3s45A-5gqfA:
undetectable		 3s45A-5gqfA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 4 ASP A 179
ASP A 178
GLY A 239
THR A 159
 None
CA  A 701 (-2.9A)
None
None
 1.37A 3tl9B-5gqfA:
undetectable		 3tl9B-5gqfA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 8 VAL A 214
LEU A 229
LEU A 232
ILE A 116
 None
 0.79A 3u5kD-5gqfA:
undetectable		 3u5kD-5gqfA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 PHE A 450
SER A 430
SER A 455
 None
 0.93A 3ufgB-5gqfA:
undetectable		 3ufgB-5gqfA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 462
VAL A 481
SER A 455
PHE A 503
ASN A 501
 None
 1.20A 4amjA-5gqfA:
undetectable		 4amjA-5gqfA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 TYR A 531
MET A 530
ILE A 592
 None
 0.83A 4c8bB-5gqfA:
undetectable		 4c8bB-5gqfA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 10 ALA A 342
ASP A 341
GLY A 250
ILE A 234
ILE A 343
 None
NAG  A 704 ( 4.2A)
None
None
None
 1.11A 4dqcA-5gqfA:
undetectable		 4dqcA-5gqfA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 8 ASP A 418
ASP A 341
ARG A 491
ASP A 411
 NAG  A 704 (-2.8A)
NAG  A 704 ( 4.2A)
None
NAG  A 704 (-3.5A)
 1.16A 4gkhF-5gqfA:
undetectable		 4gkhF-5gqfA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 345
PHE A 277
VAL A 328
THR A 158
GLY A 213
 None
 1.11A 4hvcB-5gqfA:
undetectable		 4hvcB-5gqfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 6 ASN A 333
ILE A 234
ILE A 251
VAL A 214
 None
 0.94A 4olmA-5gqfA:
undetectable		 4olmA-5gqfA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 10 THR A 159
ILE A 103
ASN A  76
VAL A  51
LEU A  90
 None
 1.43A 4r3aB-5gqfA:
undetectable		 4r3aB-5gqfA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 380
GLY A 339
ILE A 186
HIS A 364
TRP A 189
 NAG  A 704 (-3.6A)
None
None
None
None
 1.24A 4xudA-5gqfA:
undetectable		 4xudA-5gqfA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 380
GLY A 339
ILE A 186
HIS A 364
TRP A 189
 NAG  A 704 (-3.6A)
None
None
None
None
 1.35A 4xueB-5gqfA:
undetectable		 4xueB-5gqfA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 8 GLY A  46
TYR A 167
ALA A 107
GLY A  83
 None
 0.85A 5albL-5gqfA:
undetectable		 5albL-5gqfA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 4 LEU A 161
ILE A 103
GLY A 216
ILE A 168
 None
 0.72A 5dzk3-5gqfA:
undetectable
5dzkm-5gqfA:
undetectable		 5dzk3-5gqfA:
3.28
5dzkm-5gqfA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 5 ILE A 103
GLY A 216
ILE A 168
LEU A 161
 None
 0.75A 5dzkB-5gqfA:
undetectable
5dzkI-5gqfA:
undetectable
5dzkW-5gqfA:
undetectable		 5dzkB-5gqfA:
15.22
5dzkI-5gqfA:
14.08
5dzkW-5gqfA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 5 ILE A 103
GLY A 216
ILE A 168
LEU A 161
 None
 0.75A 5dzki-5gqfA:
undetectable
5dzkj-5gqfA:
undetectable
5dzkx-5gqfA:
undetectable		 5dzki-5gqfA:
14.08
5dzkj-5gqfA:
14.08
5dzkx-5gqfA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 4 ILE A 103
GLY A 216
ILE A 168
LEU A 161
 None
 0.82A 5dzkl-5gqfA:
undetectable
5dzkz-5gqfA:
undetectable		 5dzkl-5gqfA:
14.08
5dzkz-5gqfA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A 471
GLY A 422
ASP A 391
THR A 449
LEU A 601
 None
 1.19A 5hg0A-5gqfA:
undetectable		 5hg0A-5gqfA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 ILE A 175
GLY A 213
THR A 212
LEU A 173
VAL A 170
 None
 1.15A 5hw4A-5gqfA:
undetectable		 5hw4A-5gqfA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 ILE A 175
GLY A 213
THR A 212
LEU A 173
VAL A 170
 None
 1.16A 5hw4C-5gqfA:
undetectable		 5hw4C-5gqfA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 ARG A 491
PRO A 466
ASN A 442
 None
 1.05A 5jwaA-5gqfA:
undetectable
5jwaH-5gqfA:
undetectable		 5jwaA-5gqfA:
21.93
5jwaH-5gqfA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 380
GLY A 339
ILE A 186
HIS A 364
TRP A 189
 NAG  A 704 (-3.6A)
None
None
None
None
 1.34A 5lsaA-5gqfA:
undetectable		 5lsaA-5gqfA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 244
HIS A 150
HIS A 245
 NAG  A 704 (-2.7A)
GAL  A 703 (-4.0A)
GAL  A 703 (-3.9A)
 1.34A 5oexA-5gqfA:
undetectable		 5oexA-5gqfA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 244
HIS A 150
HIS A 245
 NAG  A 704 (-2.7A)
GAL  A 703 (-4.0A)
GAL  A 703 (-3.9A)
 1.38A 5oexB-5gqfA:
undetectable		 5oexB-5gqfA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 244
HIS A 150
HIS A 245
 NAG  A 704 (-2.7A)
GAL  A 703 (-4.0A)
GAL  A 703 (-3.9A)
 1.37A 5oexC-5gqfA:
undetectable		 5oexC-5gqfA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 244
HIS A 150
HIS A 245
 NAG  A 704 (-2.7A)
GAL  A 703 (-4.0A)
GAL  A 703 (-3.9A)
 1.33A 5oexD-5gqfA:
undetectable		 5oexD-5gqfA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_D_SAMD1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 11 GLY A 518
SER A 496
ASN A 516
TYR A 526
PHE A 498
 None
 1.46A 5ttfD-5gqfA:
undetectable		 5ttfD-5gqfA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 7 ALA A 321
GLY A 324
TYR A 323
TYR A 302
 None
 0.72A 5uxdA-5gqfA:
undetectable		 5uxdA-5gqfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		4 / 7 ASP A 411
ASP A 341
GLY A 340
ASN A 409
 NAG  A 704 (-3.5A)
NAG  A 704 ( 4.2A)
None
None
 1.05A 5x7pA-5gqfA:
undetectable		 5x7pA-5gqfA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 345
PHE A 277
VAL A 328
THR A 158
GLY A 213
 None
 1.12A 5xiqA-5gqfA:
undetectable		 5xiqA-5gqfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 10 TYR A 531
ASP A 541
PHE A 503
VAL A 487
TRP A 515
 None
 1.33A 6mkeC-5gqfA:
undetectable		 6mkeC-5gqfA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 10 TYR A 531
ASP A 541
PHE A 503
VAL A 487
TRP A 515
 None
 1.35A 6mkeD-5gqfA:
undetectable		 6mkeD-5gqfA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 5gqf LACTO-N-BIOSIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 345
PHE A 277
VAL A 328
THR A 158
GLY A 213
 None
 1.32A 6mn8A-5gqfA:
undetectable		 6mn8A-5gqfA:
19.68