SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJI_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.46A 4njiA-5gqoA:
undetectable		 4njiA-5gqoA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJI_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.46A 4njiB-5gqoA:
undetectable		 4njiB-5gqoA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJJ_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.47A 4njjA-5gqoA:
undetectable		 4njjA-5gqoA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJJ_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.47A 4njjB-5gqoA:
undetectable		 4njjB-5gqoA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.47A 4njkA-5gqoA:
undetectable		 4njkA-5gqoA:
30.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A  16
GLU A  99
ASN A  57
VAL A 105
ASP A  74
 None
 1.44A 4njkB-5gqoA:
undetectable		 4njkB-5gqoA:
30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5gqo SINGLE-STRANDED
DNA-BINDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A  73
SER A  75
ARG A 111
GLY A  12
 None
 0.98A 5kprA-5gqoA:
undetectable		 5kprA-5gqoA:
21.52