SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 5 TYR A 329
LEU A 316
VAL A 558
ASP A 555
 None
 1.49A 1dz6A-5gr1A:
undetectable		 1dz6A-5gr1A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		6 / 12 TYR A 329
GLN A 330
GLU A 487
HIS A 554
ASP A 555
TRP A 327
 None
None
MG  A 826 (-3.9A)
None
None
None
 1.16A 1eswA-5gr1A:
11.2		 1eswA-5gr1A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		6 / 12 TYR A 329
TRP A 399
GLU A 487
HIS A 554
ASP A 555
TRP A 327
 None
None
MG  A 826 (-3.9A)
None
None
None
 1.37A 1eswA-5gr1A:
11.2		 1eswA-5gr1A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 TYR A 587
LEU A 636
LEU A 633
HIS A 646
ILE A 750
 None
 1.20A 1fmlA-5gr1A:
undetectable		 1fmlA-5gr1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 TYR A 587
LEU A 636
LEU A 633
HIS A 646
ILE A 750
 None
 1.20A 1fmlB-5gr1A:
undetectable		 1fmlB-5gr1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 TYR A 335
PHE A 334
VAL A 471
PHE A 414
 None
 1.15A 1gsfA-5gr1A:
undetectable		 1gsfA-5gr1A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 TYR A 335
PHE A 334
VAL A 471
PHE A 414
 None
 1.15A 1gsfB-5gr1A:
undetectable		 1gsfB-5gr1A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 TYR A 335
PHE A 334
VAL A 471
PHE A 414
 None
 1.15A 1gsfD-5gr1A:
undetectable		 1gsfD-5gr1A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 5 ALA A 148
TYR A 193
ILE A 195
ASP A 207
 None
 1.07A 1upfC-5gr1A:
undetectable		 1upfC-5gr1A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 HIS A 554
ILE A 557
LEU A 613
VAL A 305
ILE A 313
 None
 1.16A 1zq9A-5gr1A:
undetectable		 1zq9A-5gr1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 11 TYR A 329
GLN A 330
ASP A 434
HIS A 554
ASP A 555
 None
None
MG  A 826 (-4.2A)
None
None
 0.76A 2owcA-5gr1A:
10.9		 2owcA-5gr1A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 11 TYR A 329
GLN A 330
HIS A 554
ASP A 555
TRP A 327
 None
 1.00A 2owcA-5gr1A:
10.9		 2owcA-5gr1A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 11 TYR A 329
GLN A 330
ASP A 434
HIS A 554
ASP A 555
 None
None
MG  A 826 (-4.2A)
None
None
 0.76A 2owwA-5gr1A:
11.0		 2owwA-5gr1A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 11 TYR A 329
GLN A 330
HIS A 554
ASP A 555
TRP A 327
 None
 1.01A 2owwA-5gr1A:
11.0		 2owwA-5gr1A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 4 TYR A 478
LEU A 475
LEU A 420
HIS A  84
 None
 1.08A 2x7hB-5gr1A:
undetectable		 2x7hB-5gr1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 2zj0D-5gr1A:
undetectable		 2zj0D-5gr1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		3 / 3 GLU A 395
HIS A 388
HIS A 384
 None
 0.90A 3co4A-5gr1A:
9.1		 3co4A-5gr1A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ALA A  43
MET A  64
GLN A  86
ILE A  77
LEU A  82
 None
 1.38A 3ia4A-5gr1A:
undetectable		 3ia4A-5gr1A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.26A 3n62A-5gr1A:
undetectable		 3n62A-5gr1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.32A 3n66B-5gr1A:
undetectable		 3n66B-5gr1A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 ILE A 177
TYR A 209
ILE A 125
ASN A 413
 None
 0.91A 3p50A-5gr1A:
undetectable		 3p50A-5gr1A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 ILE A 177
TYR A 209
ILE A 125
ASN A 413
 None
 0.91A 3p50B-5gr1A:
undetectable		 3p50B-5gr1A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 ILE A 177
TYR A 209
ILE A 125
ASN A 413
 None
 0.91A 3p50C-5gr1A:
undetectable		 3p50C-5gr1A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 ILE A 177
TYR A 209
ILE A 125
ASN A 413
 None
 0.91A 3p50D-5gr1A:
2.7		 3p50D-5gr1A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 ILE A 177
TYR A 209
ILE A 125
ASN A 413
 None
 0.92A 3p50E-5gr1A:
undetectable		 3p50E-5gr1A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 5 ALA A 389
ASN A 405
ARG A 408
HIS A 388
 None
None
GLC  A 802 (-4.1A)
None
 1.42A 3vxiA-5gr1A:
undetectable		 3vxiA-5gr1A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 6 HIS A 233
GLU A 299
ASP A 352
ASN A 357
 None
 1.17A 3vywA-5gr1A:
undetectable		 3vywA-5gr1A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 6 PRO A 208
ILE A 125
TYR A 386
PHE A 117
 None
 1.24A 4g10A-5gr1A:
undetectable		 4g10A-5gr1A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 PHE A 685
TYR A 585
GLN A 533
PHE A 668
 None
 1.46A 4grqA-5gr1A:
undetectable
4grqC-5gr1A:
undetectable		 4grqA-5gr1A:
7.50
4grqC-5gr1A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.32A 4kcnB-5gr1A:
undetectable		 4kcnB-5gr1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 LEU A 315
VAL A 361
VAL A 305
ILE A 302
 None
 1.01A 4l4cB-5gr1A:
undetectable		 4l4cB-5gr1A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 SER A 339
TYR A 212
SER A 336
GLU A 320
 None
 1.38A 4xzkA-5gr1A:
undetectable		 4xzkA-5gr1A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8A-5gr1A:
undetectable		 5hm8A-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8B-5gr1A:
undetectable		 5hm8B-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8C-5gr1A:
undetectable		 5hm8C-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8D-5gr1A:
undetectable		 5hm8D-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.39A 5hm8E-5gr1A:
undetectable		 5hm8E-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8F-5gr1A:
undetectable		 5hm8F-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 5hm8G-5gr1A:
undetectable		 5hm8G-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.39A 5hm8H-5gr1A:
undetectable		 5hm8H-5gr1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.24A 5vunA-5gr1A:
undetectable		 5vunA-5gr1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 8 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.34A 5vunB-5gr1A:
undetectable		 5vunB-5gr1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 11 HIS A 122
ILE A 177
ASN A 174
THR A 176
ILE A 125
 None
 1.33A 5y80A-5gr1A:
2.4		 5y80A-5gr1A:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 6f3mB-5gr1A:
undetectable		 6f3mB-5gr1A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 12 ASP A 113
HIS A 122
LEU A 129
GLY A 130
HIS A 132
 None
 1.40A 6f3mD-5gr1A:
undetectable		 6f3mD-5gr1A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		3 / 3 HIS A  84
ASN A  83
LEU A  82
 None
 0.85A 6f7lB-5gr1A:
undetectable		 6f7lB-5gr1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		5 / 9 ASN A 418
PHE A 414
PHE A 404
TYR A 386
VAL A 331
 None
 1.44A 6hupC-5gr1A:
2.6
6hupD-5gr1A:
1.8		 6hupC-5gr1A:
6.62
6hupD-5gr1A:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB
(Cyanothece
sp.
ATCC
51142) 		4 / 7 HIS A 516
HIS A 559
GLU A 556
GLU A 255
 GOL  A 825 (-3.8A)
None
GOL  A 825 (-3.4A)
None
 1.31A 6mn4F-5gr1A:
undetectable		 6mn4F-5gr1A:
16.02