SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 12 PHE A 113
GLY A 114
GLY A 119
LEU A 143
ALA A 148
 None
 0.63A 1v2xA-5graA:
17.0		 1v2xA-5graA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 11 THR A  81
GLY A 114
GLY A 119
LEU A 143
ALA A 148
 None
 0.75A 1x7pA-5graA:
17.8
1x7pB-5graA:
17.7		 1x7pA-5graA:
20.68
1x7pB-5graA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		3 / 3 GLY A  42
TRP A  43
VAL A  64
 None
 0.63A 3n62B-5graA:
undetectable		 3n62B-5graA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		3 / 3 GLY A  42
TRP A  43
VAL A  64
 None
 0.65A 3n65B-5graA:
undetectable		 3n65B-5graA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		3 / 3 GLY A  42
TRP A  43
VAL A  64
 None
 0.65A 3n66B-5graA:
undetectable		 3n66B-5graA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 12 GLY A  20
GLY A  16
PRO A  13
LEU A  10
LEU A  59
 None
 1.30A 4x61A-5graA:
2.0		 4x61A-5graA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 12 THR A  81
GLY A 114
GLY A 119
LEU A 145
ALA A 148
 None
 0.62A 5l0zA-5graA:
17.7		 5l0zA-5graA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 12 THR A  81
GLY A 114
LEU A 143
LEU A 145
ALA A 148
 None
 0.58A 5l0zA-5graA:
17.7		 5l0zA-5graA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 10 THR A  81
GLY A 114
GLY A 119
LEU A 145
ALA A 148
 None
 0.62A 5l0zB-5graA:
6.7		 5l0zB-5graA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		5 / 10 THR A  81
GLY A 114
LEU A 143
LEU A 145
ALA A 148
 None
 0.65A 5l0zB-5graA:
6.7		 5l0zB-5graA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gra TRNA
(CYTIDINE/URIDINE-2'
-O-)-METHYLTRANSFERA
SE TRMJ
(Zymomonas
mobilis) 		3 / 3 GLY A  42
TRP A  43
VAL A  64
 None
 0.65A 5vuoB-5graA:
undetectable		 5vuoB-5graA:
20.14