SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5grs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN
STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe)
4 / 6 ARG A 841
SER I1004
ASN A 910
SER A 876
None
1.39A 1kiaC-5grsA:
undetectable
1kiaC-5grsA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.11A 1v55C-5grsA:
undetectable
1v55N-5grsA:
undetectable
1v55P-5grsA:
undetectable
1v55C-5grsA:
20.62
1v55N-5grsA:
19.81
1v55P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
5 / 12 GLY A 808
ASP A 810
PHE A 854
SER A 822
MET A 811
None
1.21A 1wg8A-5grsA:
undetectable
1wg8A-5grsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN
STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe)
3 / 3 LYS I 992
ASP A 597
ASP A 616
None
1.14A 2br4A-5grsI:
undetectable
2br4A-5grsI:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 SER A 838
SER A 850
SER A 851
GLN I1003
None
1.08A 2cmlC-5grsA:
6.6
2cmlC-5grsA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.06A 2y69C-5grsA:
undetectable
2y69N-5grsA:
undetectable
2y69P-5grsA:
undetectable
2y69C-5grsA:
20.62
2y69N-5grsA:
19.81
2y69P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.17A 3ablA-5grsA:
undetectable
3ablC-5grsA:
undetectable
3ablP-5grsA:
undetectable
3ablA-5grsA:
19.81
3ablC-5grsA:
20.62
3ablP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.14A 3ablC-5grsA:
undetectable
3ablN-5grsA:
undetectable
3ablP-5grsA:
undetectable
3ablC-5grsA:
20.62
3ablN-5grsA:
19.81
3ablP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.14A 3abmA-5grsA:
undetectable
3abmC-5grsA:
undetectable
3abmP-5grsA:
undetectable
3abmA-5grsA:
19.81
3abmC-5grsA:
20.62
3abmP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.10A 3asnC-5grsA:
undetectable
3asnN-5grsA:
undetectable
3asnP-5grsA:
undetectable
3asnC-5grsA:
20.62
3asnN-5grsA:
19.81
3asnP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.13A 3asoA-5grsA:
undetectable
3asoC-5grsA:
undetectable
3asoP-5grsA:
undetectable
3asoA-5grsA:
19.81
3asoC-5grsA:
20.62
3asoP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.09A 3asoC-5grsA:
undetectable
3asoN-5grsA:
undetectable
3asoP-5grsA:
undetectable
3asoC-5grsA:
20.62
3asoN-5grsA:
19.81
3asoP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
5 / 11 PHE A 854
LEU A 880
PHE A 847
VAL A 849
PHE A 802
None
1.44A 3u9fN-5grsA:
undetectable
3u9fO-5grsA:
undetectable
3u9fN-5grsA:
19.44
3u9fO-5grsA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.13A 3wg7A-5grsA:
undetectable
3wg7C-5grsA:
undetectable
3wg7P-5grsA:
undetectable
3wg7A-5grsA:
19.81
3wg7C-5grsA:
20.62
3wg7P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.10A 3wg7C-5grsA:
undetectable
3wg7N-5grsA:
undetectable
3wg7P-5grsA:
undetectable
3wg7C-5grsA:
20.62
3wg7N-5grsA:
19.81
3wg7P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.18A 3x2qA-5grsA:
undetectable
3x2qC-5grsA:
undetectable
3x2qP-5grsA:
undetectable
3x2qA-5grsA:
19.81
3x2qC-5grsA:
20.62
3x2qP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.16A 3x2qC-5grsA:
undetectable
3x2qN-5grsA:
undetectable
3x2qP-5grsA:
undetectable
3x2qC-5grsA:
20.62
3x2qN-5grsA:
19.81
3x2qP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 6 VAL A 809
LEU A 825
ILE A 828
VAL A 835
None
0.94A 4a9kA-5grsA:
undetectable
4a9kA-5grsA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 6 VAL I1030
LEU A 624
ILE I1052
VAL I1043
None
0.93A 4a9kA-5grsI:
undetectable
4a9kA-5grsI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.14A 5b1aA-5grsA:
undetectable
5b1aC-5grsA:
undetectable
5b1aP-5grsA:
undetectable
5b1aA-5grsA:
19.81
5b1aC-5grsA:
20.62
5b1aP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.11A 5b3sA-5grsA:
undetectable
5b3sC-5grsA:
undetectable
5b3sP-5grsA:
undetectable
5b3sA-5grsA:
19.81
5b3sC-5grsA:
20.62
5b3sP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 5 SER A 612
ALA A 611
HIS A 594
LEU A 619
None
1.49A 5dzkb-5grsA:
undetectable
5dzkp-5grsA:
undetectable
5dzkb-5grsA:
17.96
5dzkp-5grsA:
0.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.17A 5iy5C-5grsA:
undetectable
5iy5N-5grsA:
undetectable
5iy5P-5grsA:
undetectable
5iy5C-5grsA:
20.63
5iy5N-5grsA:
19.81
5iy5P-5grsA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.08A 5w97A-5grsA:
undetectable
5w97C-5grsA:
undetectable
5w97c-5grsA:
undetectable
5w97A-5grsA:
19.81
5w97C-5grsA:
20.62
5w97c-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.14A 5w97C-5grsA:
undetectable
5w97a-5grsA:
undetectable
5w97c-5grsA:
undetectable
5w97C-5grsA:
20.62
5w97a-5grsA:
19.81
5w97c-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.15A 5wauA-5grsA:
undetectable
5wauC-5grsA:
undetectable
5wauc-5grsA:
undetectable
5wauA-5grsA:
19.81
5wauC-5grsA:
20.62
5wauc-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.15A 5wauC-5grsA:
undetectable
5waua-5grsA:
undetectable
5wauc-5grsA:
undetectable
5wauC-5grsA:
20.62
5waua-5grsA:
19.81
5wauc-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.13A 5x19A-5grsA:
undetectable
5x19C-5grsA:
undetectable
5x19P-5grsA:
undetectable
5x19A-5grsA:
19.81
5x19C-5grsA:
20.62
5x19P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.15A 5x1bA-5grsA:
undetectable
5x1bC-5grsA:
undetectable
5x1bP-5grsA:
undetectable
5x1bA-5grsA:
19.81
5x1bC-5grsA:
20.62
5x1bP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.11A 5x1fA-5grsA:
undetectable
5x1fC-5grsA:
undetectable
5x1fP-5grsA:
undetectable
5x1fA-5grsA:
19.81
5x1fC-5grsA:
20.62
5x1fP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.13A 5xdqA-5grsA:
undetectable
5xdqC-5grsA:
undetectable
5xdqP-5grsA:
undetectable
5xdqA-5grsA:
19.81
5xdqC-5grsA:
20.62
5xdqP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.11A 5xdqC-5grsA:
undetectable
5xdqN-5grsA:
undetectable
5xdqP-5grsA:
undetectable
5xdqC-5grsA:
20.62
5xdqN-5grsA:
19.81
5xdqP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.14A 5xdxC-5grsA:
undetectable
5xdxN-5grsA:
undetectable
5xdxP-5grsA:
undetectable
5xdxC-5grsA:
20.90
5xdxN-5grsA:
19.81
5xdxP-5grsA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.11A 5z84A-5grsA:
undetectable
5z84C-5grsA:
undetectable
5z84P-5grsA:
undetectable
5z84A-5grsA:
19.81
5z84C-5grsA:
20.62
5z84P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.11A 5z84C-5grsA:
undetectable
5z84N-5grsA:
undetectable
5z84P-5grsA:
undetectable
5z84C-5grsA:
20.62
5z84N-5grsA:
19.81
5z84P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.13A 5z85A-5grsA:
undetectable
5z85C-5grsA:
undetectable
5z85P-5grsA:
undetectable
5z85A-5grsA:
19.81
5z85C-5grsA:
20.62
5z85P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.10A 5z85C-5grsA:
undetectable
5z85N-5grsA:
undetectable
5z85P-5grsA:
undetectable
5z85C-5grsA:
20.62
5z85N-5grsA:
19.81
5z85P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.14A 5z86A-5grsA:
undetectable
5z86C-5grsA:
undetectable
5z86P-5grsA:
undetectable
5z86A-5grsA:
19.81
5z86C-5grsA:
20.62
5z86P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.12A 5z86C-5grsA:
undetectable
5z86N-5grsA:
undetectable
5z86P-5grsA:
undetectable
5z86C-5grsA:
20.62
5z86N-5grsA:
19.81
5z86P-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.14A 5zcoA-5grsA:
undetectable
5zcoC-5grsA:
undetectable
5zcoP-5grsA:
undetectable
5zcoA-5grsA:
19.81
5zcoC-5grsA:
20.62
5zcoP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.11A 5zcoC-5grsA:
undetectable
5zcoN-5grsA:
undetectable
5zcoP-5grsA:
undetectable
5zcoC-5grsA:
20.62
5zcoN-5grsA:
19.81
5zcoP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.12A 5zcpA-5grsA:
undetectable
5zcpC-5grsA:
undetectable
5zcpP-5grsA:
undetectable
5zcpA-5grsA:
19.81
5zcpC-5grsA:
20.62
5zcpP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.12A 5zcpC-5grsA:
undetectable
5zcpN-5grsA:
undetectable
5zcpP-5grsA:
undetectable
5zcpC-5grsA:
20.62
5zcpN-5grsA:
19.81
5zcpP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.11A 5zcqA-5grsA:
undetectable
5zcqC-5grsA:
undetectable
5zcqP-5grsA:
undetectable
5zcqA-5grsA:
19.81
5zcqC-5grsA:
20.62
5zcqP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 674
ASP A 727
THR A 720
TRP A 773
None
1.16A 6nknC-5grsA:
undetectable
6nknN-5grsA:
undetectable
6nknP-5grsA:
undetectable
6nknC-5grsA:
20.62
6nknN-5grsA:
19.81
6nknP-5grsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5grs STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomy
ces
pombe)
4 / 7 ASP A 727
THR A 720
TRP A 773
LEU A 674
None
1.16A 6nmfA-5grsA:
undetectable
6nmfC-5grsA:
undetectable
6nmfP-5grsA:
undetectable
6nmfA-5grsA:
19.81
6nmfC-5grsA:
20.62
6nmfP-5grsA:
20.62